dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0051682 | ||||||||
| Uniprot Accession | F2Z461; HERC6_MOUSE; Q3UEA7; Q9CU70; | ||||||||
| Genbank Protein ID | NP_080268.1; | ||||||||
| Genbank Nucleotide ID | NM_025992.2; | ||||||||
| Protein Name | E3 ISG15--protein ligase Herc6 | ||||||||
| Protein Synonyms/Alias | |||||||||
| Gene Name | Herc6 | ||||||||
| Gene Synonyms/Alias | |||||||||
| Organism | Mus musculus(Mouse) | ||||||||
| NCBI Taxa ID | 10090 | ||||||||
| Functional Description (View all) |
Major E3 ligase for ISG15 conjugation. Acts as a positive regulator of innate antiviral response in cells induced by interferon. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
|
||||||||
| Sequence (Fasta) | MYFSWAAGSR KPRRLKAGTS GIELLQAASG EHHSLLLFSN HRVYSCGDNS WGQLGQRRDQ 60 STERPEPIQA LNDLHVDLVS CGKEHSVAVC HKGKVFAWGA GSEGQLGIGE FKEISFMPTK 120 IKALAGIKII QVSCGHYHSL ALSEDGHVFS WGRNSEGQLG LGKNSRSQAI PQKVKSLEGI 180 PLAQVAAGGT HSFALSLTGT SFGWGSNRSG QLALSGNKVK EQIYKPHSIG ALKNLSVIYI 240 SCGYEHTAVL TEEGQVFTFG GNSSGQLQPS PRSGQRGPQL IEGIGGRVSQ IECASYHTIA 300 YVYTTGQVVS LGRGPSHTSN PTHQEAPAEN SDITCLLAAE DLVDIEVKDI FAGAHANFVT 360 TRRVSHTRST GVSMKILPEI IRINQSLVKK WRAANKRKDR EGAKREISLI FSSSACLTAS 420 FLKKRDAGEN NLIDVDLKLA RDVFKKLTTE KWISSLITTC LEEYLLRDLP YSSPHQEALL 480 VFLLLPECSI MQDPKNWKTL AFEFAKAIHK MGPQSLAFLR TCWASLEVSS LNILVQMLKK 540 AIISQIQYGV ATEQYITNIK VLLEVIKEVH KANCQLPESA FIINELSGIF NFDAEAGRMF 600 IRHNDLDCTE SSDMVVFSDF LFVFDLPSKI KLMKCDSFVK LMSEVMAFPE KMSSPPYLIL 660 KVRRSHLVED TLRQLRQVED FDLRKQLSVG FINEIRPEAG GVSSEFFHCI FEEMTDPKYE 720 MFIYPEKGSS MWFPVNPKFE KSSYFLFGIL CGLSLHNLKV INLPFPLALY KKLLNQKPSL 780 EDLKELSLPL GRNLQEVLNC EAGDIEELHM YFSIYWDQKD VDLIPDGISV PVNETNKRDY 840 VSKYVDYIFN ISIKTIYEEF HRGFYKVCNW DIIRQFQPEE LMTAIIGNAT CDWKQFENNS 900 KYKDGYDKSH PTILLFWKAF HDLTLDEKKK FLLFLTGCDR LHVKGLQNEG IVFRCSETFS 960 EEDNPRSLTC HRMLDLPKYS SMRRMKEALQ VAINNSTGFV SQE 1004 |
||||||||
| Keyword | KW-0181--Complete proteome |
||||||||
| Interpro | IPR000569--HECT_dom |
||||||||
| PROSITE | |||||||||
| Pfam | |||||||||
| Gene Ontology | GO:0005737--C:cytoplasm |