dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0051514
Uniprot Accession F1M5H6; F1M5H6_RAT;
Genbank Protein ID XP_001063503.3; XP_223012.6;
Genbank Nucleotide ID XM_001063503.5; XM_223012.8;
Protein Name Protein Tp53bp2
Protein Synonyms/Alias
Gene Name Tp53bp2
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
334QKENLPVSPDGNPPQPhosphoSitePlus;curated22135298; 23712012; 21630457
479GTLRKNQSSEDILRDPhosphoSitePlus;curated22135298; 23984901
555PQARVLLSPSAPSGGPhosphoSitePlus;curated22135298; 23712012; 21630457
697ERIPRPLSPTKLLPFPhosphoSitePlus;curated22135298; 23712012; 21630457; 23984901
736RPLKKRSSITEPEGPcurated23984901
783SVTVNPESPIEIPNPPhosphoSitePlus;curated22135298; 23712012; 21630457
Sequence
(Fasta)		MRFGSKMMPM FLTVYLSNSE QHFTEVPVTP ETVCRDVVDL CKEPGESDCH LAEVWCGSER 60
PVADNERMFD VLQRFGSQRN EVRFFLRHER PPNRDIVSGP RSQDAGVKRN GVKVPGEHRR 120
KENGVNSPRL DLTLAELQEM ASRQQQQIEA QQQMLATKEQ RLKFLKQQDQ RQQQQAAEQE 180
KLKRLREIAE SQEAKLKKVR ALKGHVEQKR LSNGKLVEEI EQMNSLFQQK QRELVLAVSK 240
VEELTRQLEM LKNGRIDGHH DNQSAVAELD RLYKELQLRN KLNQEQNAKL QQQRECLNKR 300
NSEVAVMDKR VNELRDRLWK KKAALQQKEN LPVSPDGNPP QQAVSAPSRV AAVGPYMQSS 360
TMPRMPSRPE LLGKPALPDS SLVMQSAEGP MKIQTLPNMR SGAASQSKGP KAHSASSDWN 420
PSSTDLLPSQ GSGSALDQVD EGEIALREKE KKVRPFSMFD TVDQCAPPPS FGTLRKNQSS 480
EDILRDAQTV NKNVAKVPPP VPTKPKQINL PYFGQTAQSS SDVKPDGNPQ QLPIAATSMG 540
AKLKPAGPQA RVLLSPSAPS GGQDQVLSPA SKQESPPAAA VRPFTPQPSK DTFPPAFRKP 600
QTVAASSIYS MYTQHQVPGK NFQQAVQSAS TKTHPRGPHF SSVYGKPVIA AAQNPQQHPE 660
NIYSCSQGKP GSPEPETEPV SSVHESHENE RIPRPLSPTK LLPFLSNPYR NQSDADLEAL 720
RKKLSNAPRP LKKRSSITEP EGPNGPNIQK LLYQRTTIAA METISVPSYP SKSPSSVTVN 780
PESPIEIPNP YLHVEPEKEA GSLVPEPLSP EDMGSASTEN SDMPAPPPGL ECVSEGVPDN 840
STTLQDNTEG TNPEAPHLLE VYLEEYPPYP PPPYPSGEPE VSEEDSARMR PPEVTGQVSL 900
PPGKRTNLRK TGSERIAHGM RVKFNPLALL LDSSLEGEFD LVQRIIYEVD DPSLPNDEGI 960
TALHNAVCAG HTEIVKFLVQ FGVNVNAADS DGWTPLHCAA SCNNVQVCKF LVESGAAVFA 1020
MTYSDMQTAA DKCEEMEEGY TQCSQFLYGV QEKMGIMNKG VIYALWDYQP QHDDELLLKE 1080
GDCMAVVRRE DEDETEWWWA RLNDKEGYVP RNLLGLYPRI KPRQRSLA 1129
Keyword

KW-0040--ANK repeat
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0728--SH3 domain
Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001452--SH3_domain
IPR029071--Ubiquitin-rel_dom
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50002--SH3
Pfam

PF00018--SH3_1
Gene Ontology

GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0007417--P:central nervous system development
GO:0009792--P:embryo development ending in birth or egg hatching
GO:0007507--P:heart development
GO:0072332--P:intrinsic apoptotic signaling pathway by p53 class mediator
GO:1900119--P:positive regulation of execution phase of apoptosis
GO:1901216--P:positive regulation of neuron death
GO:0010212--P:response to ionizing radiation