dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0051075
Uniprot Accession E9QMR2; E9QMR2_MOUSE;
Genbank Protein ID NP_598835.2;
Genbank Nucleotide ID NM_134074.2;
Protein Name Dedicator of cytokinesis protein 9
Protein Synonyms/Alias
Gene Name Dock9
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
20RKFTRALSKPGTAAEPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 21183079
24RALSKPGTAAELRQSPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 21183079
441ALMNGGQSPPAFQDAPHOSIDA21081558
1272RNPEKSNSLDKQQSGPhosphoSitePlus;curated22135298; 21183079
Sequence
(Fasta)
MAQQQLPVST ETRKFTRALS KPGTAAELRQ SVSEVVRGSV LLAKPKLIEP LDYENVIVQK 60
KTQILNDCLR EMLLFPYDDF QTAILRRQGR YLRSTVPANA EEEAQSLFVT ECIKTYNSDW 120
HLVTYKYEDY SGEFRQLPNK VPKLDKLPVH VYEVDEEADK DEDAASLGSQ KGGITKHGWL 180
YKGNMNSAIS VTMRSFKRRF FHLIQLGDGS YNLNFYKDEK ISKEPKGSIF LDSCMGVIQN 240
NRVRRFAFEL KMQDKSSYLL AADSEAEMEE WVTVLNKILQ LNFEAAMQEK RNGDPHEDDE 300
QSKLEGSGSG LDSYLPELAK STREAEIKLK SESRVKLFYL DPDTQKLDFS SAEPEVKPFE 360
EKFGKRILVK CNDLSFNLQC CVAENEEGPT TNVEPFFVTL SLFDIKYNRK ISADFHVDLN 420
HFSVRQMLTP TSPALMNGGQ SPPAFQDALH TAMQYPKQGI FSVTCPHPDI FLVARIEKVL 480
QGSITHCAEP YMRSSDSSKV AQKVLKNAKQ ACQRLGQYRM PFAWAARTLF KDTSGNLDKN 540
ARFSAIYRQD SNKLSNDDML KLLADFRKPE KMAKLPVILG NLDITIDSVS CDFPNYLNSS 600
YIPMRQFETC SKSPITFEVE EFVPCIPKHT QPYTVYSNHL YVYPKYLKYD SQKSFAKARN 660
IAICIEFKDS DEEDSQPLKC IYGRPGGPVF TRSALAAVLH HQQNPEFYDE IKIELPAQLH 720
ERHHLLFTFF HVSCDNSTKG STKKKDAVET QVGFSWLPLL KDGRVLTSEQ HIPVSANLPS 780
GYLGYQELGM GRHYGPEVKW VEGGKPLLKI STHLVSTVYT QDQHLHNFFQ YCQKTESGAQ 840
ASGSELVKYL KSLHAMEGHV MIAFLPTILN QLFRVLTRAT QEEVAVNVTR VIIHVVAQCH 900
EEGLESHLRS YVKFAYKAEP YVASEYKTVH EELTKSMTTI LKPSADFLTS NKLLKYSWFF 960
FDVLIKSMAQ HLIENNKVKL LRNQRFPASY HHAVETVVNM LMPHITQKFR DNPEASKNAN 1020
HSLAVFIKRC FTFMDRGFVF KQINNYISCF APGDPKTLFE YKFEFLRVVC NHEHYIPLNL 1080
PMPFGKGRIQ RYQDLQLDYS LTDEFCRNHF LVGLLLREVG TALQEFREVR VIAISMLKNL 1140
LIKHSFDDRY NSRSHQARIA TLYLPLFGLL IENVQRINVR DVSPFPVNPG SIVKDEALAV 1200
PAGNPLMTPQ KGNTLDHSLH KDLLGAISGI ASPYTASTPN INSVRNADSR GSLISTDSGN 1260
SLPDRNPEKS NSLDKQQSGM LGNSVVRCDK LDQSEIKSLL MCFLYVLKSM SDDALFTYWN 1320
KASTAELMDF FTISEVCLHQ FQYMGKRYIA SVRKISSVLG ISVDNGYGHS EADVVHQSLL 1380
EANIATEVCL TALDTLSLFT LAFKNQLLAD HGHNPLMKKV FDVYLCFLQK HQSEMALKNV 1440
FTALRSLIYK FPSAFYEGRA DMCASLCYEV LKCCNSKLSS IRTEASQLLY FLMRNNFDYT 1500
GKKSFVRTHL QVIISVSQLI ADVVGIGGTR FQQSLSIINN CANSDRIIKH TSFSSDVKDL 1560
TKRIRTVLMA TAQMKEHEND PEMLVDLQYS LAKSYASTPE LRKTWLDSMA RIHVKNGDLS 1620
EAAMCYVHVT ALVAEYLTRK GMFRQGCTAF RVITPNIDEE ASMMEDVGMQ DVHFNEDVLM 1680
ELLEQCADGL WKAERYELIA DIYKLIIPIY EKRRDFERLA HLYDTLHRAY SKVTEVMHSG 1740
RRLLGTYFRV AFFGQGFFED EDGKEYIYKE PKLTPLSEIS QRLLKLYSDK FGSENVKMIQ 1800
DSGKVNPKDL DSKFAYIQVT HVTPFFDEKE LQERRTEFER CHNIRRFMFE MPFTQTGKRQ 1860
GGVEEQCKRR TILTAIHCFP YVKKRIPVMY QHHTDLNPIE VAIDEMSKKV AELRQLCSSA 1920
EVDMIKLQLK LQGSVSVQVN AGPLAYARAF LDDTNTKRYP DNKVKLLKEV FRQFVEACGQ 1980
ALAVNERLIK EDQLEYQEEM KANYREMAKE LSDIMREQIC PLEEKTSVLP NSLHIFNAIS 2040
GTPTSTVVQG LTSSSSVV 2059
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR027007--DHR-1_domain
IPR027357--DHR-2
IPR026791--DOCK
IPR026796--DOCK9
IPR010703--DOCK_C
IPR021816--DOCK_C/D_N
IPR011993--PH/PTB_dom
IPR001849--PH_domain

PROSITE

PS51650--DHR_1
PS51651--DHR_2
PS50003--PH_DOMAIN

Pfam

PF06920--DHR-2
PF14429--DOCK-C2
PF11878--DUF3398
PF00169--PH

Gene Ontology

GO:0005622--C:intracellular
GO:0016020--C:membrane
GO:0017048--F:Rho GTPase binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043547--P:positive regulation of GTPase activity
GO:0007264--P:small GTPase mediated signal transduction