dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0051071
Uniprot Accession E9QM77; E9QM77_MOUSE;
Genbank Protein ID NP_033151.2;
Genbank Nucleotide ID NM_009125.2;
Protein Name Ataxin-2
Protein Synonyms/Alias
Gene Name Atxn2
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
523NGGVPWPSPCPSPSScurated23684622; 22817900; 21183079
527PWPSPCPSPSSRPPScurated23684622; 22817900; 21183079
529PSPCPSPSSRPPSRYcurated23684622
534SPSSRPPSRYQSGPNcurated23684622
551PPRAATPTRPPSRPPcurated22817900; 21183079
Sequence
(Fasta)
MRSSTAAAQR PAAGDPEPRR PAGWAARRSL PRTARRGGRG GAVAYPSAGP PPRGPGAPPR 60
GPRSPPCASD CFGSNGHGAS RPGSRRLLGV CGPPRPFVVV LLPLAPAATP ARACPPGVRA 120
SPPRSGVSSS ARPAPGCPRP ACEPVYGPLT MSLKPQPQPP APATGRKPGG GLLSSPGAAP 180
ASAAVTSASV VPAPAAPVAS SSAAAGGGRP GLGRGRNSSK GLPQPTISFD GIYANVRMVH 240
ILTSVVGSKC EVQVKNGGIY EGVFKTYSPK CDLVLDAAHE KSTESSSGPK REEIMESVLF 300
KCSDFVVVQF KDTDSSYARR DAFTDSALSA KVNGEHKEKD LEPWDAGELT ASEELELEND 360
VSNGWDPNDM FRYNEENYGV VSTYDSSLSS YTVPLERDNS EEFLKREARA NQLAEEIESS 420
AQYKARVALE NDDRSEEEKY TAVQRNCSDR EGHGPNTRDN KYIPPGQRNR EVLSWGSGRQ 480
SSPRMGQPGP GSMPSRAASH TSDFNPNAGS DQRVVNGGVP WPSPCPSPSS RPPSRYQSGP 540
NSLPPRAATP TRPPSRPPSR PSRPPSHPSA HGSPAPVSTM PKRMSSEGPP RMSPKAQRHP 600
RNHRVSAGRG SMSSGLEFVS HNPPSEAAAP PVARTSPAGG TWSSVVSGVP RLSPKTHRPR 660
SPRQSSIGNS PSGPVLASPQ AGIIPAEAVS MPVPAASPTP ASPASNRALT PSIEAKDSRL 720
QDQRQNSPAG SKENVKASET SPSFSKADNK GMSPVVSEHR KQIDDLKKFK NDFRLQPSST 780
SESMDQLLSK NREGEKSRDL IKDKTEASAK DSFIDSSSSS SNCTSGSSKT NSPSISPSML 840
SNAEHKRGPE VTSQGVQTSS PACKQEKDDR EEKKDTTEQV RKSTLNPNAK EFNPRSFSQP 900
KPSTTPTSPR PQAQPSPSMV GHQQPAPVYT QPVCFAPNMM YPVPVSPGVQ PLYPIPMTPM 960
PVNQAKTYRA GKVPNMPQQR QDQHHQSTMM HPASAAGPPI VATPPAYSTQ YVAYSPQQFP 1020
NQPLVQHVPH YQSQHPHVYS PVIQGNARMM APPAHAQPGL VSSSAAQFGA HEQTHAMYAC 1080
PKLPYNKETS PSFYFAISTG SLAQQYAHPN AALHPHTPHP QPSATPTGQQ QSQHGGSHPA 1140
PSPVQHHQHQ AAQALHLASP QQQSAIYHAG LAPTPPSMTP ASNTQSPQSS FPAAQQTVFT 1200
IHPSHVQPAY TTPPHMAHVP QAHVQSGMVP SHPTAHAPMM LMTTQPPGGP QAALAQSALQ 1260
PIPVSTTAHF PYMTHPSVQA HHQQQL 1287
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR010920--LSM_dom
IPR009604--LsmAD_domain
IPR025852--SM_dom_ATX

PROSITE
Pfam

PF06741--LsmAD
PF07145--PAM2
PF14438--SM-ATX

Gene Ontology

GO:0005737--C:cytoplasm
GO:0010494--C:cytoplasmic stress granule
GO:0005794--C:Golgi apparatus
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005844--C:polysome
GO:0030529--C:ribonucleoprotein complex
GO:0005802--C:trans-Golgi network
GO:0005154--F:epidermal growth factor receptor binding
GO:0044822--F:poly(A) RNA binding
GO:0008022--F:protein C-terminus binding
GO:0021702--P:cerebellar Purkinje cell differentiation
GO:0033962--P:cytoplasmic mRNA processing body assembly
GO:0048872--P:homeostasis of number of cells
GO:0040015--P:negative regulation of multicellular organism growth
GO:0002091--P:negative regulation of receptor internalization
GO:0050905--P:neuromuscular process
GO:0048812--P:neuron projection morphogenesis
GO:0010603--P:regulation of cytoplasmic mRNA processing body assembly
GO:0034063--P:stress granule assembly