dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0051069
Uniprot Accession E9QLW6; E9QLW6_MOUSE;
Genbank Protein ID NP_032667.2;
Genbank Nucleotide ID NM_008641.3;
Protein Name Microtubule-associated serine/threonine-protein kinase 2
Protein Synonyms/Alias
Gene Name Mast2
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
67QDMVTGLSPLLFRKLPhosphoSitePlus;curated22135298; 21183079
Sequence
(Fasta)		MKRSRCRERP QPPPARREDA APRTAELPQP QSLPPRRRAP PGRQLLEERS GPLGHDSREQ 60
DMVTGLSPLL FRKLSNPDIF APTGKVKLQR QLSQDDCKLR RGSLASSLSG KQLLPLSSSV 120
HSSVGQVTWQ STGEASNLVR MRNQSLGQSA PSLTAGLKEL SLPRRGSFCR TSNRKSLIVT 180
SSTSPTLPRP HSPLHGHTGN SPLDSPRNFS PNAPAHFSFV PARRTDGRRW SLASLPSSGY 240
GTNTPSSTVS SSCSSQEKLH QLPFQPTADE LHFLTKHFST ENVPDEEGRR SPAMRPRSRS 300
LSPGRSPVSF DSEIIMMNHV YKERFPKATA QMEERLADFI SSNTPDSVLP LADGALSFIH 360
HQVIEMARDC LDKSRSGLIT SHYFYELQEN LEKLLQDAHE RSESSDVAFV IQLVKKLMII 420
IARPARLLEC LEFDPEEFYH LLEAAEGHAK EGHGIKCDIP RYIVSQLGLT RDPLEEMAQL 480
SSYDSPDTPE TDDSVEGRGV SQPSQKTPSE EDFETIKLIS NGAYGAVFLV RHKSTRQRFA 540
MKKINKQNLI LRNQIQQAFV ERDILTFAEN PFVVSMFCSF ETKRHLCMVM EYVEGGDCAT 600
LLKNIGALPV DMVRLYFAET VLALEYLHNY GIVHRDLKPD NLLITSMGHI KLTDFGLSKI 660
GLMSLTTNLY EGHIEKDARE FLDKQVCGTP EYIAPEVILR QGYGKPVDWW AMGIILYEFL 720
VGCVPFFGDT PEELFGQVIS DEIVWPEGDD ALPPDAQDLT SKLLHQNPLE RLGTSSAYEV 780
KQHPFFMGLD WTGLLRQKAE FIPQLESEDD TSYFDTRSER YHHVDSEDEE EVSEDGCLEI 840
RQFSSCSPRF SKVYSSMERL SLLEERRTPP PTKRSLSEEK EDHSDGLAGL KGRDRSWVIG 900
SPEILRKRLS VSESSHTESD SSPPMTVRHR CSGLPDGPHC PEETSSTPRK QQQEGIWVLI 960
PPSGEGSSRP VPERPLERQL KLDEEPPGQS SRCCPALETR GRGTPQLAEE ATAKAISDLA 1020
VRRARHRLLS GDSIEKRTTR PVNKVIKSAS ATALSLLIPS EHHACSPLAS PMSPHSQSSN 1080
PSSRDSSPSR DFLPALGSLR PPIIIHRAGK KYGFTLRAIR VYMGDTDVYT VHHMVWHVED 1140
GGPASEAGLR QGDLITHVNG EPVHGLVHTE VVELVLKSGN KVSISTTPLE NTSIKVGPAR 1200
KGSYKAKMAR RSKRSKGKDG QESRKRSSLF RKITKQASLL HTSRSLSSLN RSLSSGESGP 1260
GSPTHSHSLS PRSPPQGYRV APDAVHSVGG NSSQSSSPSS SVPSSPAGSG HTRPSSLHGL 1320
APKLQRQYRS PRRKSAGSIP LSPLAHTPSP PATAASPQRS PSPLSGHGSQ SFPTKLHLSP 1380
PLGRQLSRPK SAEPPRSPLL KRVQSAEKLA AALAAAEKKL APSRKHSLDL PHGELKKELT 1440
PREASPLEVV GTRSVLSGKG PLPGKGVLQP APSRALGTLR QDRAERRESL QKQEAIREVD 1500
SSEDDTDEEP ENSQATQEPR LSPHPEASHN LLPKGSGEGT EEDTFLHRDL KKQGPVLSGL 1560
VTGATLGSPR VDVPGLSPRK LSRPQAFEEA TNPLQVPSLS RSGPTSPTPS EGCWKAQHLH 1620
TQALTALCPS FSELTPTGCS AATSTSGKPG TWSWKFLIEG PDRASTNKTI TRKGEPANSQ 1680
DTNTTVPNLL KNLSPEEEKP QPPSVPGLTH PLLEVPSQNW PWESECEQME KEEPSLSITE 1740
VPDSSGDRRQ DIPCRAHPLS PETRPSLLWK SQELGGQQDH QDLALTSDEL LKQT 1795
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR015022--MA_Ser/Thr_Kinase_dom
IPR028779--MAST2
IPR023142--MAST_pre-PK_dom
IPR001478--PDZ
IPR000719--Prot_kinase_dom
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS51285--AGC_KINASE_CTER
PS50106--PDZ
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF08926--DUF1908
PF00595--PDZ
PF00069--Pkinase
Gene Ontology

GO:0005737--C:cytoplasm
GO:0015630--C:microtubule cytoskeleton
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0008017--F:microtubule binding
GO:0019902--F:phosphatase binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0007010--P:cytoskeleton organization
GO:0035556--P:intracellular signal transduction
GO:0018105--P:peptidyl-serine phosphorylation
GO:0045075--P:regulation of interleukin-12 biosynthetic process