dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0051068
Uniprot Accession E9QLW5; E9QLW5_MOUSE;
Genbank Protein ID NP_034644.2;
Genbank Nucleotide ID NM_010514.3;
Protein Name Insulin-like growth factor II
Protein Synonyms/Alias
Gene Name Igf2
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
4----MGGSVAGFQVPPhosphoSitePlus22135298
Sequence
(Fasta)
MGGSVAGFQV PMGIPVGKSM LVLLISLAFA LCCIAAYGPG ETLCGGELVD TLQFVCSDRG 60
FYFSRPSSRA NRRSRGIVEE CCFRSCDLAL LETYCATPAK SERDVSTSQA VLPDDFPRYP 120
VGKFFQYDTW RQSAGRLRRG LPALLRARRG RMLAKELKEF REAKRHRPLI VLPPKDPAHG 180
GASSEMSSNH Q 192
Keyword

KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0964--Secreted
KW-0732--Signal

Interpro

IPR022334--IGF2
IPR013576--IGF2_C
IPR016179--Insulin-like
IPR022350--Insulin-like_growth_factor
IPR022353--Insulin_CS
IPR022352--Insulin_family

PROSITE

PS00262--INSULIN

Pfam

PF08365--IGF2_C
PF00049--Insulin

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0008083--F:growth factor activity
GO:0005158--F:insulin receptor binding
GO:0005159--F:insulin-like growth factor receptor binding
GO:0031017--P:exocrine pancreas development
GO:0009887--P:organ morphogenesis
GO:0042104--P:positive regulation of activated T cell proliferation
GO:0046628--P:positive regulation of insulin receptor signaling pathway
GO:0043410--P:positive regulation of MAPK cascade
GO:0045840--P:positive regulation of mitotic nuclear division
GO:0040018--P:positive regulation of multicellular organism growth
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0051146--P:striated muscle cell differentiation