dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0051060
Uniprot Accession E9QKQ5; E9QKQ5_MOUSE;
Genbank Protein ID NP_001123884.1; NP_766538.2;
Genbank Nucleotide ID NM_001130412.1; NM_172950.3;
Protein Name Phosphatidate phosphatase LPIN1
Protein Synonyms/Alias
Gene Name Lpin1
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
175KRDDNVNTSEDEDMFPHOSIDA;curated21081558; 23684622; 21743459
176RDDNVNTSEDEDMFPPHOSIDA;curated21081558; 23684622; 21183079
187DMFPIEMSSDEDTAPPHOSIDA;curated21081558; 23684622; 21743459
188MFPIEMSSDEDTAPMPHOSIDA;curated21081558; 23684622; 21743459
228STYPQSASYPSSDREcurated21743459
243WSPSPSPSGSRPSTPcurated23684622
248SPSGSRPSTPKSDSEcurated23684622
Sequence
(Fasta)
MNYVGQLAGQ VFVTVKELYK GLNPATLSGC IDIIVIRQPN GSLQCSPFHV RFGKMGVLRS 60
REKVVDIEIN GESVDLHMKL GDNGEAFFVQ ETDNDQEIIP MYLATSPILS EGAARMESQL 120
KRNSVDRIRC LDPTTAAQGL PPSDTPSTGS LGKKRRKRRR KAQLDNLKRD DNVNTSEDED 180
MFPIEMSSDE DTAPMDGSRT LPNDVPPFQD DIPKENFPSI STYPQSASYP SSDREWSPSP 240
SPSGSRPSTP KSDSELVSKS ADRLTPKNNL EMLWLWGELP QAAKSSSPHK MKESSPLGSR 300
KTPDKMNFQA IHSESSDTFS DQSPTMARGL LIHQSKAQTE MQFVNEEDLE SLGAAAPPSP 360
VAEELKAPYP NTAQSSSKTD SPSRKKDKRS RHLGADGVYL DDLTDMDPEV AALYFPKNGD 420
PGGLPKQASD NGARSANQSP QSVGGSGIDS GVESTSDSLR DLPSIAISLC GGLSDHREIT 480
KDAFLEQAVS YQQFADNPAI IDDPNLVVKV GNKYYNWTTA APLLLAMQAF QKPLPKATVE 540
SIMRDKMPKK GGRWWFSWRG RNATIKEESK PEQCLTGKGH NTGEQPAQLG LATRIKHESS 600
SSDEEHAAAK PSGSSHLSLL SNVSYKKTLR LTSEQLKSLK LKNGPNDVVF SVTTQYQGTC 660
RCEGTIYLWN WDDKVIISDI DGTITRSDTL GHILPTLGKD WTHQGIAKLY HKVSQNGYKF 720
LYCSARAIGM ADMTRGYLHW VNERGTVLPQ GPLLLSPSSL FSALHREVIE KKPEKFKVQC 780
LTDIKNLFFP NTEPFYAAFG NRPADVYSYK QVGVSLNRIF TVNPKGELVQ EHAKTNISSY 840
VRLCEVVDHV FPLLKRSHSC DFPCSDTFSN FTFWREPLPP FENQDMHSAS A 892
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR023214--HAD-like_dom
IPR031703--Lipin_mid
IPR007651--Lipin_N
IPR013209--LNS2
IPR031315--LNS2/PITP
IPR028794--LPIN1

PROSITE
Pfam

PF16876--Lipin_mid
PF04571--Lipin_N
PF08235--LNS2

Gene Ontology

GO:0005634--C:nucleus
GO:0005667--C:transcription factor complex
GO:0042826--F:histone deacetylase binding
GO:0008195--F:phosphatidate phosphatase activity
GO:0001085--F:RNA polymerase II transcription factor binding
GO:0031532--P:actin cytoskeleton reorganization
GO:0032869--P:cellular response to insulin stimulus
GO:0016311--P:dephosphorylation
GO:0009062--P:fatty acid catabolic process
GO:0006629--P:lipid metabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0031065--P:positive regulation of histone deacetylation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0045598--P:regulation of fat cell differentiation
GO:0031529--P:ruffle organization
GO:0019432--P:triglyceride biosynthetic process