dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0051058
Uniprot Accession E9QKH0; E9QKH0_MOUSE;
Genbank Protein ID XP_011246409.1;
Genbank Nucleotide ID XM_011248107.1;
Protein Name CLIP-associating protein 1
Protein Synonyms/Alias
Gene Name Clasp1
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
646RIRTRRQSSGSTTNVPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 23684622; 25521595
647IRTRRQSSGSTTNVAPhosphoSitePlus;curated22135298; 23684622; 25521595
649TRRQSSGSTTNVASTPhosphoSitePlus;curated22135298; 23684622
650RRQSSGSTTNVASTPPhosphoSitePlus22135298
651RQSSGSTTNVASTPSPhosphoSitePlus22135298
655GSTTNVASTPSDSRGPhosphoSitePlus22135298
658TNVASTPSDSRGRSRPhosphoSitePlus22135298
Sequence
(Fasta)		MEPRMESCLA QVLQKDVGKR LQVGQELIDY FSDRQKSADL EHDQTLLDKL VDGLATSWVN 60
SSNYKVVLLG MDILSALVTR LQDRFKAQIG TVLPSLIDRL GDAKDSVREQ DQTLLLKIMD 120
QAANPQYVWD RMLGGFKHKN FRTREGICLC LIATLNASGA QTLTLSKIVP HICNLLGDPN 180
SQVRDAAINS LVEIYRHVGE RVRADLSKKG LPQSRLNVIF TKFDEVQKSG NMIQSANEKN 240
FDDEDSVDGN RPSSASSSSS KAPSSSRRNV NLGTTRRLMS SSLGSKSSAA KEGAGAVDEE 300
DFIKAFDDVP VVQIYSSRDL EESINKIREI LSDDKHDWEQ RVNALKKIRS LLLAGAAEYD 360
NFFQHLRLLD GAFKLSAKDL RSQVVREACI TLGHLSSVLG NKFDHGAEAI MPTIFNLIPN 420
SAKIMATSGV VAVRLIIRHT HIPRLIPVIT SNCTSKSVAV RRRCFEFLDL LLQEWQTHSL 480
ERHISVLAET IKKGIHDADS EARIEARKCY WGFHSHFSRE AEHLYHTLES SYQKALQSHL 540
KNSDSIVSLP QSDRSSSSSQ ESLNRPLSAK RSPTGSTASR GSTVSTKSVS TTGSLQRSRS 600
DIDVNAAASA KSKVSSSSGS PAFSSAAALP PGSYASLGRI RTRRQSSGST TNVASTPSDS 660
RGRSRAKVVS QSQRSRSANP AGAGSRSSSP GKLLGSGLAG GSSRGPPVTP SSEKRSKIPR 720
SQGCSRETSP NRIGLARSSR IPRPSMSQGC SRDTSRESSR DTSPARGFTP LDRFGLGQSG 780
RIPGSVNAMR VLSTSTDLEA AVADALKKPV RRRYEPYGMY SDDDANSDAS SVCSERSYGS 840
RNGGIPHYLR QTEDVAEVLN HCASSNWSER KEGLLGLQNL LKSQRTLSRV ELKRLCEIFT 900
RMFADPHSKR VFSMFLETLV DFIIIHKDDL QDWLFVLLTQ LLKKMGADLL GSVQAKVQKA 960
LDVTRDSFPF DQQFNILMRF IVDQTQTPNL KVKVAILKYI ESLARQMDPT DFVNSSETRL 1020
AVSRIITWTT EPKSSDVRKA AQIVLISLFE LNTPEFTMLL GALPKTFQDG ATKLLHNHLK 1080
NSSNTGVGSP SNTIGRTPSR HPSSRTSPLT SPTNCSHGGL SPSRLWGWSA DGLSKPPPPF 1140
SQPNSIPTAP SHKTLRRSYS PSMLDYDTEN LNSEEIYSSL RGVTEAIEKF SFRSQEDLNE 1200
PIKRDGKKDC DIVSRDGGAA SPATEGRGGS EIEGGRMALD NKTSLLNTQP PRAFPGPRAR 1260
EYNPYPYSDT INTYDKTALK EAVFDDDMEQ LRDVPIDHSD LVADLLKELS NHNERVEERK 1320
GALLELLKIT REDSLGVWEE HFKTILLLLL ETLGDKDHSI RALALRVLRE ILRNQPARFK 1380
NYAELTIMKT LEAHKDSHKE VVRAAEEAAS TLASSIHPEQ CIKVLCPIIQ TADYPINLAA 1440
IKMQTKVVER ITKESLLQLL VDIIPGLLQG YDNTESSVRK ASVFCLVAIY SVIGEDLKPH 1500
LAQLTGSKMK LLNLYIKRAQ TTNSNSSSSS DVSTHS 1537
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR028399--CLASP_metazoan
IPR024395--CLASP_N_dom
IPR021133--HEAT_type_2
PROSITE

PS50077--HEAT_REPEAT
Pfam

PF12348--CLASP_N
Gene Ontology

GO:0045180--C:basal cortex
GO:0005938--C:cell cortex
GO:0031592--C:centrosomal corona
GO:0005813--C:centrosome
GO:0030981--C:cortical microtubule cytoskeleton
GO:0005881--C:cytoplasmic microtubule
GO:0070062--C:extracellular exosome
GO:0005794--C:Golgi apparatus
GO:0000776--C:kinetochore
GO:0005828--C:kinetochore microtubule
GO:0016020--C:membrane
GO:0005876--C:spindle microtubule
GO:0002162--F:dystroglycan binding
GO:0043515--F:kinetochore binding
GO:0008017--F:microtubule binding
GO:0051010--F:microtubule plus-end binding
GO:0030953--P:astral microtubule organization
GO:0051301--P:cell division
GO:0040001--P:establishment of mitotic spindle localization
GO:0051294--P:establishment of spindle orientation
GO:0010458--P:exit from mitosis
GO:0007030--P:Golgi organization
GO:0034453--P:microtubule anchoring
GO:0001578--P:microtubule bundle formation
GO:0000226--P:microtubule cytoskeleton organization
GO:0007020--P:microtubule nucleation
GO:0031023--P:microtubule organizing center organization
GO:0007052--P:mitotic spindle organization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0031111--P:negative regulation of microtubule polymerization or depolymerization
GO:0051497--P:negative regulation of stress fiber assembly
GO:1903690--P:negative regulation of wound healing, spreading of epidermal cells
GO:1904261--P:positive regulation of basement membrane assembly involved in embryonic body morphogenesis
GO:0010634--P:positive regulation of epithelial cell migration
GO:0045921--P:positive regulation of exocytosis
GO:0090091--P:positive regulation of extracellular matrix disassembly
GO:0010717--P:regulation of epithelial to mesenchymal transition
GO:0051893--P:regulation of focal adhesion assembly
GO:0010470--P:regulation of gastrulation
GO:0070507--P:regulation of microtubule cytoskeleton organization
GO:0006903--P:vesicle targeting