dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0051057
Uniprot Accession E9QK89; E9QK89_MOUSE;
Genbank Protein ID NP_001010833.2; XP_006524323.1; XP_006524324.1;
Genbank Nucleotide ID NM_001010833.2; XM_006524260.1; XM_006524261.2;
Protein Name Mediator of DNA damage checkpoint protein 1
Protein Synonyms/Alias
Gene Name Mdc1
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
385HTPMVINSDTDEEEEPHOSIDA;curated21081558; 21743459
387PMVINSDTDEEEEEEPHOSIDA;curated21081558; 21743459
Sequence
(Fasta)
MESTQVIDWD AEEEEETELS SGSLGYSVEP IGQLRLFSGT HGPERDFPLY LGKNVVGRSP 60
DCSVALPFPS ISKQHAVIEI SAWNKAPILQ DCGSLNGTQI VKPPRVLPPG VSHRLRDQEL 120
ILFADFPCQY HRLDVPPPLV PRSLLTIEKT PRIRIESQNS RVLLAADSEE EGDFPSGRCV 180
ANGQRNTASP SATVVPESDE EVSSPAPSVP GPSSPFGLGS DTDEEQGQQP GVEESSLADS 240
SGAAGEAEQP EANGTTAGIQ AQPTEHKLKD TKVKKEAGRA GVSDGSVLER SPTLGEDSDT 300
EVDEDHKPGF ADSETDVEEE RIPVTPPVAP VKKNQVLLAV GIGDPEAPGV AHLQDCLAGS 360
GTDVEDKTAL DVPLERNHTP MVINSDTDEE EEEEEEEVSA ALTLAHLKER GIGLWSRDPG 420
AEEVKSQPQV LVEQSQSASG RDSDTDVEEE SSGRKREIIP DSPMDVDEAL TVTQPESQPP 480
RRPNDADEYM DMSSPGSHLV VNQASFAVVG KTRAQVEEEV PGPSVILGEK HQVPLEGAQP 540
PEEAWETAVQ EGSSSPEAAA SVRPSQQPVA EDAGTECATA VSEQESTLEV RSQSGSPAAP 600
VEQVVIHTDT SGDPTLPQRE GAQTPTGRER EAHVGRTKSA KECCDAEPED LCLPATQCFV 660
EGESQHPEAV QSLENEPTQL FPCTLPQEPG PSHLSLQTPG ADTLDVPWEV LATQPFCLRE 720
QSETSELHEA HGSQPSLPRE PPGHQHLVHT SPVHTELLRI EGREIQTVEK AMGIPKEMAD 780
RMTPEREPLE REIRGRTENS ERDVIGEELI QGTKDREPKK VLARDSQRKE ADKDLEGNRE 840
SLEVEIEMSK DSQKRERKVE KPEPKREWEP ADLEVTPDRG VTEEGSHDQK GQIASLTLKP 900
GVGVKDLEGL ASAPIITGSQ ADGGKGDPLS PGRQQRGRLS CQTTPAGKAS RGDPEPPDHC 960
LFSSVPEAST QSLLTSQSQK QSTPQPLFST SSSEIPLPES LHTKPNVRPR RSSRMTPSPH 1020
SSAALKPNTT CPTNQPAASR PTSRPTRGRA NRSSTRTPEL IVPVDPELQP STSTEQPVIP 1080
KLTSQVTEGR VQMPEPLLTG PEIQSPTSTE QSVTPDRKPR ATRGRPSKSP NKTPEPLIST 1140
GPELQPPTSI EQPVIPKPTS RVTRGRPRKS SVRTPESVVS TGPELQPLTS IEQPVIPEPR 1200
ATRGRPSKSS IKTPESVVPT GPELQPLTSA KQPVTPNLTS RASRGRSSKS IRTPEPVVQT 1260
GPEFHPSTST EQPDTREPSS QARTRRSAVK TPEASVPTTP ELQPFTSKKQ PAPKPTALVT 1320
QGRTYKPSTE DCESVGPVAP DFEPSTSTDH LVTPKVTDQS LTLQSSPLSA SPVSSTPDLK 1380
PPVPIAQPVT PEPIPQANHQ RKRRAAGKQG SRTVPLGHKS YSALSEPEPQ SSASQSSGAS 1440
EADSPRQKRP RRQASQKTVV IKEEPVETEV KEEPQETAIP TPEKRKRDHA EEVTQGKPTR 1500
SRRTKPNQET APKVLFTGVM DSRGERAVLA LGGSLASSVN EASHLVTDRI RRTVKFLCAL 1560
GKGIPILSLN WLYQSRKAGC FLPPDDYLVT DPEQEKNFSF SLRDSLCRAR ERRLLEDYEI 1620
HVTPGVQPPP PQMGEIISCC GGTFLPSMPH SYKLHRVIIT CTEDLPRCAI PSRLGLPLLS 1680
PEFLLTGVLK QEATPEAFVL SNLEMSST 1709
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001357--BRCT_dom
IPR000253--FHA_dom
IPR008984--SMAD_FHA_domain

PROSITE

PS50172--BRCT
PS50006--FHA_DOMAIN

Pfam

PF00498--FHA

Gene Ontology

GO:0005925--C:focal adhesion
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0070975--F:FHA domain binding
GO:0008022--F:protein C-terminus binding