dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0051042
Uniprot Accession E9QAN8; E9QAN8_MOUSE;
Genbank Protein ID NP_001092746.2; XP_006529594.1; XP_006529595.1;
Genbank Nucleotide ID NM_001099276.2; XM_006529531.2; XM_006529532.1;
Protein Name Protein Pik3c2b
Protein Synonyms/Alias
Gene Name Pik3c2b
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
178PPRKGSPSPSKISQPPhosphoSitePlus22135298
Sequence
(Fasta)		MSSTQGNGEH WKSLESVGIS RKELAMAEAL QMEYDALSRL RHHKEESRAK QNTEPSLISW 60
DEPALDFYSK PAGRRTDLKL LRGLSGSDPT LNYNSISPPE GLPNSTSQDP QPGPDPWPKG 120
SLSGDYLYIF DGSEGRCSLS PGSGDTDGSC KKLSPPPLPP RVSIWDAPPL PPRKGSPSPS 180
KISQPNDINS FSSAEQPPDK LLVAQDPEEG ELPDGRGQGH TLGSVDYDGI NDAITRLNLK 240
STYDSEISSD ATRGWKEGRG PLDFNKDTSG KPVARSKTMP PQVPPRTYTS RYANRKNATP 300
GNNRRISAAP VGSRPHTVAN GHELFEVSEE RDEEVAAFCH MLDILRTGSD IQDYSLTGCV 360
WSTVTPSPEH LGDEVNLKVT VLCDSLREPL TFTCNCSSTV DLLIHQTLCY THDELREVDV 420
GDFVLKPCGL EEFLQNKHAL GSHEYIQYCR KFDISIRLQL MEQKAIRSDL ARTVNDDQSP 480
STLNYLIHLQ ERPVKQTISR QALSLLFDTY HNEVDAFLLA DGDFPLKADR VVQSVKAICN 540
ALAAVETPEI TSALNQLPPC PSRMQPKIQK DPSVLSVREN REKVVEALTA AILDLVELYC 600
STFNADFQTA VPGSRKHDLV QEACHFPGAL AFTVYGTHRI PIIWATSYED FYLSCSLSHG 660
GKELCSPLQT RRAHFSKYLF HLIIWDQQIC FPVQVNRLPR ETLLCATLYA LPVPPPGGSS 720
EANKQKRVPE ALGWVTTPLF NFRQVLTCGR KLLGLWPATQ ENSGARWSAP NFHQPDSVIL 780
QIDFPSSAFD IKFTSPPGDK FSPRYEFGSL REEDQRKLKD ITQKESLYWL TDADKKQLWE 840
KRYYCHTEVS SLPLVLASAP SWEWACLPDI YALLQQWTHM NHQDALGLLH ATFPDQEVRR 900
MAVQWIGSLS DAELLDYLPQ LVQALKYECY LDSPLVRFLL KRAISDLRVT HYFFWLLKDS 960
LKDSQFSIRY QYLLAALLCC CGKGLREEFN RQCWLVNTLA KLAQQVREAT PSARQGILRV 1020
GLEEVKQFFA LNGSCRLPLS PSLLVKGIVP RDCSYFNSNA VPLKLAFQNV DPLGENIRVI 1080
FKCGDDLRQD MLTLQMIRIM SKIWVQEGLD MRMVIFRCFS TGRGKGMVEM IPNAETLRKI 1140
QVEHGVTGSF KDRPLADWLQ KHNPGEDEYE KAVENFIYSC AGCCVATYIL GICDRHNDNI 1200
MLKTTGHMFH IDFGRFLGHA QMFGNIKRDR APFVFTSDMA YVINGGDKPS SRFHDFVDLC 1260
CQAYNLIRKH THLFLNLLGL MLSCGIPELS DLEDLKYVYD ALRPQDTEAN ATTYFTRLIE 1320
SSLGSVATKL NFFIHNLAQM KFTGSDDRLT LSFAPRTHTL KSSGRIRDVF LCRHEKIFHP 1380
SKGYVYVVKV MRENAHEATY IQRTFEEFQE LHNKLRLLFP SSFLPSFPSR FVIGRSRGEA 1440
VAERRKEELN GYIWHLIHAA PEVAECDLVY TFFHPLPRDE KASGPSPAPK SSDGTWARPV 1500
GKVGGEVKLS ISYKNNKLFI MVMHIRGLQP LQDGNDPDPY VKIYLLPDPQ KTTKRKTKVA 1560
RKTCNPTYNE MLVYDGIPKG DLQQRELQLS VLSEQGFWEN LLLGEVHIRL RELDLAQEKT 1620
GWFGLGSRGH GT 1633
Keyword

KW-0181--Complete proteome
KW-0418--Kinase
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR016024--ARM-type_fold
IPR000008--C2_dom
IPR011009--Kinase-like_dom
IPR001683--Phox
IPR000403--PI3/4_kinase_cat_dom
IPR018936--PI3/4_kinase_CS
IPR002420--PI3K_C2_dom
IPR000341--PI3K_Ras-bd_dom
IPR015433--PI_Kinase
IPR001263--PInositide-3_kin_accessory_dom
IPR029071--Ubiquitin-rel_dom
PROSITE

PS50004--C2
PS00915--PI3_4_KINASE_1
PS00916--PI3_4_KINASE_2
PS50290--PI3_4_KINASE_3
PS51547--PI3K_C2
PS51546--PI3K_RBD
PS51545--PIK_HELICAL
PS50195--PX
Pfam

PF00168--C2
PF00454--PI3_PI4_kinase
PF00792--PI3K_C2
PF00794--PI3K_rbd
PF00613--PI3Ka
PF00787--PX
Gene Ontology

GO:0005737--C:cytoplasm
GO:0030139--C:endocytic vesicle
GO:0005942--C:phosphatidylinositol 3-kinase complex
GO:0005886--C:plasma membrane
GO:0016303--F:1-phosphatidylinositol-3-kinase activity
GO:0035005--F:1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0005524--F:ATP binding
GO:0001727--F:lipid kinase activity
GO:0035091--F:phosphatidylinositol binding
GO:0002250--P:adaptive immune response
GO:0060326--P:cell chemotaxis
GO:0006954--P:inflammatory response
GO:0045087--P:innate immune response
GO:0014065--P:phosphatidylinositol 3-kinase signaling
GO:0046854--P:phosphatidylinositol phosphorylation
GO:0036092--P:phosphatidylinositol-3-phosphate biosynthetic process
GO:0030168--P:platelet activation
GO:0043491--P:protein kinase B signaling
GO:0006468--P:protein phosphorylation