dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0051012
Uniprot Accession E9Q9K8; E9Q9K8_MOUSE;
Genbank Protein ID NP_932779.2; XP_006515891.1;
Genbank Nucleotide ID NM_198111.2; XM_006515828.2;
Protein Name Protein Akap6
Protein Synonyms/Alias
Gene Name Akap6
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 31 (View all)
PositionPeptidesSourceReferences ( PMIDs )
423LKPELSRSTPSLVEPPhosphoSitePlus;curated22135298; 21183079
424KPELSRSTPSLVEPPPHOSIDA;PhosphoSitePlus21081558; 22135298
454SPSAASQSYECLHKVPhosphoSitePlus22135298
480HIKEISSSLGRLTDCPhosphoSitePlus22135298
533SVVPTMVSPGAPKATPhosphoSitePlus22135298
592LGSDNIKSPLPLLSKPhosphoSitePlus22135298
692KKHTRLGTVSPSSSScurated25521595
703SSSSDIASSLGESIEcurated25521595
704SSSDIASSLGESIESPhosphoSitePlus22135298
715SIESGPLSDILSDEDcurated25521595
1070SGPRDLLSPESGSLVPHOSIDA;PhosphoSitePlus;SysPTM 2.0;curated21081558; 22135298; 18056256; 19366988; 21183079
1321TVLTKSLSKDSSFSScurated21183079
1427SVSQASVSPVGCVNGPhosphoSitePlus22135298
1547SDIEKALTGIQNARQPhosphoSitePlus22135298
1556IQNARQLSLLSRSSSPhosphoSitePlus22135298
1559ARQLSLLSRSSSVESPhosphoSitePlus22135298
1566SRSSSVESLSPGGDLPHOSIDA;PhosphoSitePlus21081558; 22135298
1585IFKNGSDSLQRSTSLPhosphoSitePlus22135298
1591DSLQRSTSLESWLTSPhosphoSitePlus;curated22135298; 21183079
1594QRSTSLESWLTSYKSPhosphoSitePlus;curated22135298; 21183079
Sequence
(Fasta)
MLTMSVTLSP LRSQDPDPMA TDASPMAINM TPTVEQEEGE GEEAVKDVGA EQQYGKPPPL 60
HTAADWKIVL HLPEIETWLR MTSERVRDLT YSVQQDADSK HVDVHLVQLK DICEDISDHV 120
EQIHALLETE FSLKLLSYSV NVIVDIHAVQ LLWHQLRVSV LVLRERILQG LQDANGNYTR 180
QTDILQAFSE ETTEGRLDSL TEVDDSGQLT IKCSQNYLSL DCGITAFELS DYSPSEDLLG 240
GLGDMTTSQA KTKSFDSWSY SEMEKEFPEL IRSVGLLTVA TEPVPSSCGA ANEDSSQVIL 300
SEDHRGGHEE DGALEPGEQL GSTLETSSLG DTLTNAAEHP PETANQDSTS SPQLGAKKSQ 360
PGPCEMMTPK RSIRDCFNYN EDSPTQPTLP KRGLFLKETL KNERRGSDGK GRVVDLKPEL 420
SRSTPSLVEP PDRSKLCLVL QSSYPSSPSA ASQSYECLHK VGIGNLENIV RSHIKEISSS 480
LGRLTDCHKE KPRLKKPHKT LAEVSLCKIP KRGTGSGKQS ENTRSSVVPT MVSPGAPKAT 540
ARPATDSAST TSGDTCHQRN RGGKLPAQSK ASSSSPCSHS SESSLGSDNI KSPLPLLSKS 600
QKGSPPAPCH ATQNGQVVEA WYGSDEYLAL PSHLKQTEVL ALKLENLTKL LPQKPRGETI 660
QDIDDWELSE MNSDSEIYPT YHIKKKHTRL GTVSPSSSSD IASSLGESIE SGPLSDILSD 720
EDLCMPLSGM KKFTDEKSER PSSSEKNESH SATKSALIQK LMKDIQHQDN YEAIWERIEG 780
FVNKLDEFIQ WLNEAMETTE NWTPPKAETD SLRLYLETHL SFKLNVDSHC ALKEAVEEEG 840
HQLLELIASH KAGLKDMLKM IASQWKELQR QIKRQHSWIL RALDTIKAEI LATDVSVEDE 900
EGTGSPKAEA QLCYLEAQRD AVEQMSLKLY SEQYTSGSKR KEEFADMSKA HSVGSNGLLD 960
FDSEYQELWD WLIDMESLVM DSHDLMMSEE QQQHLYKRYS VEMSIRHLKK TELLSKVEAL 1020
KKGGLSLPND ILEKVDSINE KWELLGKTLR EKIQDTMAGH SGSGPRDLLS PESGSLVRQL 1080
EVRIKELKRW LRDTELFIFN SCLRQEKEGT SAEKQLQYFK SLCHEIKQRR RGVASILRLC 1140
QHLLDDRDTC NLNADHQPMQ LIIVNLERRW EAIVMQAVQW QTRLRKKMGK ESETLNVIDP 1200
GLMDLNGMSE DALEWDETDI SNKLISVHEE SNDLDQDLEP MVPTVKLEET HHKDSGYEEE 1260
AGDCGGSQYT SNITAPSSPH IYQVYSLHNV EFHEDSHTQF LKSSPKFTGT VQPTVLTKSL 1320
SKDSSFSSTK SLPDLLGGSS LVRPYSCQSG DLSQNSGSES GIVSEGDNEM PTNSDMSLFS 1380
MVDGSPSNPE TQHLDPQMGD AANVLEQKFK DEGECIKLSS VSQASVSPVG CVNGKAGDLN 1440
SITKHTTDCL GDELQGKHEV FTFYDYSYLQ GSKLKFPMIM KQPQSEKAHL EDPLLRGFYF 1500
DKKSCKPKHQ TSESQPDAPL HEKILASAPH EMGRSSYKSS DIEKALTGIQ NARQLSLLSR 1560
SSSVESLSPG GDLFGLGIFK NGSDSLQRST SLESWLTSYK SNEDLFSCHS SGDISVSSGS 1620
VGELSKRTLD LLNRLENIQS PSEQKIKRSV SDITLQSSSQ KMSFSGQMSL DVASSINEDS 1680
PASLTELSSS DELSLCSEDI VLHKNKVPES NASFRKRLNR SVADESDVNV SMIVNVSCTS 1740
ACTDDEDDSD LLSSSTLTLT EEELCLKDED DDSSIATDDE IYEESNLMSG LDYIKNELQT 1800
WIRPKLSLSR EKKRPSVTDE IKVNKDGGST ERANPSDTLD IEALLNCSIK RLSENNGNGK 1860
NPPRTHDLGT KGENKKNTYD VTKDPHVADM ENGNVESTPE REKEKPEIPE ASANLASNVK 1920
KISESKHDEY EALMDGSDDS SVTGKEFGPP NDRHPPQIGA DPQHPERGDC TSVQNSCSGL 1980
LLETGGGSRQ DSDGLKSLSN DAPSVARNAA GCCLLEQNET EESASISSST SCCNCKPDVF 2040
HQKDDEDCSV HDFVKEIIDM ASTALKSKSQ PESEVAAPTS LTQIKEKVLE HSHRPIHLRK 2100
GDFYSYLSLS SHDSDCGEVT NYIDEKSNTP LPPDTVDSGL DDKEDVDCFF EACVEDEPAD 2160
EEARLSSALP NESEVQDEAA KPEQMTASSS VFRDETDTVP LSGLSPQKGA DDAKEGDGAS 2220
HTSQGCVESA EPTTPPGKAK REGSSRKQSV SGTPEENAAS AKPKIQAFSL NAKQPKGKAA 2280
LYPSPQTLTC KEKLVSFHED RHSNMHR 2308
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR026696--AKAP6/CEP68
IPR018159--Spectrin/alpha-actinin
IPR002017--Spectrin_repeat

PROSITE
Pfam

PF00435--Spectrin

Gene Ontology

GO:0034704--C:calcium channel complex
GO:0005635--C:nuclear envelope
GO:0031965--C:nuclear membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0016529--C:sarcoplasmic reticulum
GO:0008179--F:adenylate cyclase binding
GO:0044325--F:ion channel binding
GO:0051018--F:protein kinase A binding
GO:0071320--P:cellular response to cAMP
GO:1902261--P:positive regulation of delayed rectifier potassium channel activity
GO:1901381--P:positive regulation of potassium ion transmembrane transport
GO:0060306--P:regulation of membrane repolarization