dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0051007
Uniprot Accession E9Q9D5; RBL2A_MOUSE; Q3TDG7; Q8K2P9; Q9D133;
Genbank Protein ID NP_081093.2; XP_011244020.1;
Genbank Nucleotide ID NM_026817.3; XM_011245718.1;
Protein Name Rab-like protein 2A
Protein Synonyms/Alias
Gene Name Rabl2
Gene Synonyms/Alias Rabl2a;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)		 Plays an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. Binds, in a GTP-regulated manner, to a specific set of effector proteins including key proteins involved in cilia development and function and delivers them into the growing sperm tail.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
147QMTQKNFSFAKKFSLcurated25338131
Sequence
(Fasta)		MAGDRNRHCE LEQEKYDTHE NVKIICLGDS AVGKSKLMER FLMDGFQPQQ LSTYALTLYK 60
HTATVDGKTI LVDFWDTAGQ ERFQSMHASY YHKAHACIMV FDVQRKITYK NLGTWYAELR 120
EFRPEIPCIL VANKIDADIQ MTQKNFSFAK KFSLPLYFVS AADGTNVVKL FNDAIRLAVA 180
YKESSQDFMD EVLQELENFK LEQKEEDTSG QEQSDTTKSP SPS 224
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0342--GTP-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
Interpro

IPR027417--P-loop_NTPase
IPR005225--Small_GTP-bd_dom
IPR001806--Small_GTPase
PROSITE
Pfam

PF00071--Ras
Gene Ontology

GO:0005622--C:intracellular
GO:0030992--C:intraciliary transport particle B
GO:0097225--C:sperm midpiece
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0042384--P:cilium assembly
GO:0006886--P:intracellular protein transport
GO:0032482--P:Rab protein signal transduction
GO:0007338--P:single fertilization
GO:0030317--P:sperm motility