dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0051001
Uniprot Accession E9Q983; E9Q983_MOUSE;
Genbank Protein ID XP_011245187.1;
Genbank Nucleotide ID XM_011246885.1;
Protein Name Supervillin
Protein Synonyms/Alias
Gene Name Svil
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
258PTEARARYPSGSEIPcurated23684622
260EARARYPSGSEIPVVPhosphoSitePlus;curated22135298; 21183079
262RARYPSGSEIPVVEDPhosphoSitePlus;curated22135298; 23684622
Sequence
(Fasta)
MKRKERIARR LEGIENDSQP ILLQSCTGLV THRLLEEDTP RYMRATDPAS PHIGRSKEEE 60
DTPGSSLEKQ TPSKYCIETS GIHSSGSMDT HSLESKAERI ARYKAERRRQ LAEKYGLTLD 120
PEADSEYLSR YAKSRKDPDV TERRGKSDKQ EEQSKDANSR HSRTESGPRT SLVASQDCTP 180
LGSNMSDQEQ LLNVENQRRV QDPPLGEDGS SAFFSERSIS FPEVPRSPKQ IPSSPLQQPA 240
SPNHPGDSPL PTEARARYPS GSEIPVVEDE EKVDERAKLS VAAKRLLFRE MEKSFDEHTV 300
PKRHSRNAAV EQRLRRLQDR SHTQPITTEE VVIAATLQAS AHQKALARDQ ANEGRESAEP 360
GEPDSSTLSL AEKLALFNKL SQPVSKAIST RNRIDVRQRR MNARYQTQPV TLGEVEQVQS 420
GKLISFSPTV NTSVSIMASA VAPTYAGDLR KLSVDNNTSA TDYKSPPAEN SDSPVRSILK 480
PQAWRPLVEH SGSKGMPGES GKTESKNALT VAAEDSGVQT RGAFEEEEEP SYPILGRVRE 540
GDGQKEPKHV VLRRGSLELG NPSAAHLGDE LKEVSTAKSS LQENLDLKDK QASEENTDVE 600
TVMRKFSLKE FGETTSEQTE VAARKASVQM ATPGAWKQQE SSEQLAEKLF KNPCAMFASG 660
EVKVPVGDSF LDSPSKTMSI KERLALLKKS GEEDWKNRLI RKQEYGKATG GLHTQEVEQS 720
LKKKRVTESR ESQMTIEERK HLITVREEAW KTKGRGAAND STQFTVAGRM VKKGLASPTS 780
ITPISSPLCS KSRGTTPVSK PLEDIEARPD MQLESDLKLD RLETFLRRLN NKVAGIQETV 840
LTVTGKSVKE VMKLDDDETF AKFYRSVDHS IPRSPVELEE DFDVIFDPYA PKLTSSVAEH 900
KRQVRPKRRV QASKNPLKLL AARDDLLQEY TEQRLNVAFM ESKRMKVEKM SSNSNFSEVT 960
LAGLASRENF SNINLRSVNL MEQNSNNSAM PYKKLMLLQI KGRRHVQTRL VEPRASSLNS 1020
GDCFLLLSPQ YCFLWVGEFS NVIEKAKASE LATLIQTKRE LGCRATYIQT IEEGINTHTH 1080
AAKDFWKLLG GQTSYQSAGD PKEDELYETA IIETNCVYRL TDDKLVPDDD YWGKIPKCSL 1140
LQSKEVLVFD FGSEVYVWHG KEVTLAQRKI AFQLAKHLWN GTFDYENCDI NPLDPGECNP 1200
LIPRKGQGRP DWAIFGRVTE HNETILFKEK FLDWTELKRP TEKNSGEVVQ QKDDPRADVK 1260
PYDVTRMVAT PQITAGTILD GVNVGRGYGL VEGDDRRQFE IATVSVDVWH ILEFDYSRLP 1320
RQSIGQFHEG DAYVVKWKYM ASTAVGSRQK GEHLVRVAGK EKCVYFFWQG RHSTVSEKGT 1380
SALMTVELDE ERGAQVQVLQ GKEPPCFLQC FQGGMVVHSG RREEEEENVQ SEWRLYCVRG 1440
EVPMEGNLLE VACHCSSLRS RTSMVVLNIN KALIYLWHGC KAQGHTKEVG RTAANKIKEE 1500
CPLEAGLHSS SNVTIHECDE GSEPLGFWDA LGRRDRKAYD CMLQDPGSFN FAPRLFILSS 1560
SSGDFSATEF VYPAQAPSAV SSMPFLQEDL YSAPQPALFL VDNHHEVYLW QGWWPTENKI 1620
TGSARIRWAS DRKSAMETVL QYCRGKNLKR PPPKSYLIHA GLEPLTFTNM FPSWEHREDI 1680
AEITEMDTEV SNQITLVEDV LAKLCKTIYP LADLLARPLP EGVDPLKLEI YLTDEDFEFA 1740
LDMSRDEFNA LPTWKQVNLK KSKGLF 1767
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR029006--ADF-H/Gelsolin-like_dom
IPR007123--Gelsolin-like_dom
IPR015628--SV/p205
IPR007122--Villin/Gelsolin
IPR003128--Villin_headpiece

PROSITE

PS51089--HP

Pfam

PF00626--Gelsolin
PF02209--VHP

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0043034--C:costamere
GO:0005737--C:cytoplasm
GO:0005925--C:focal adhesion
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0051015--F:actin filament binding
GO:0007010--P:cytoskeleton organization
GO:0007519--P:skeletal muscle tissue development