dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050989
Uniprot Accession E9Q8T1; E9Q8T1_MOUSE;
Genbank Protein ID NP_001004468.1;
Genbank Nucleotide ID NM_001004468.2;
Protein Name Transforming acidic coiled-coil-containing protein 2
Protein Synonyms/Alias
Gene Name Tacc2
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 12
PositionPeptidesSourceReferences ( PMIDs )
86EARGPEGSPLPRSSLPhosphoSitePlus;curated22135298; 22817900; 21183079
166SMAARTPSAEGDKELcurated21183079
520RVVAREESRSHGDNLcurated21183079
657WESSRSQTKSPVMLQPhosphoSitePlus;curated22135298; 22817900; 21183079
659SSRSQTKSPVMLQDRPhosphoSitePlus;curated22135298; 21743459; 22817900; 21183079
776QDCQRKLSCPEDSLPPhosphoSitePlus;curated22135298; 22817900; 21183079
781KLSCPEDSLPPSPKNPhosphoSitePlus;SysPTM 2.0;curated22135298; 17242355; 19366988; 22817900; 21183079
785PEDSLPPSPKNRLQPPhosphoSitePlus;SysPTM 2.0;curated22135298; 17242355; 19366988; 22817900; 21183079
947TGQGLSKSQQELDDAPhosphoSitePlus22135298
1826AGPGVEVTPTASPQHPhosphoSitePlus;curated22135298; 22817900; 21183079
1830VEVTPTASPQHLAKNPhosphoSitePlus;curated22135298; 22817900; 21183079
2417VNETKFNSPSEGKQLPhosphoSitePlus22135298
Sequence
(Fasta)		MGNENSTSDH QRTSSVQSPR SLQPPGKSQS LQKQQGDLPG SCAGSTGLGG SCSASESVAS 60
LDPCTVSPEV AEQGEHPQEA RGPEGSPLPR SSLPWEQPCP SASMPFTEGP SEGCLASSEA 120
EAPEDSTLTN HLRMEPSPNI PGNILPTSTP EVDGPTQHSM AARTPSAEGD KELKEEGPNS 180
SSNRTGQLPG ISLVPLQEPR TELLSGEGTG PRDFEFQRKE DMDDCPSPES ATKAPAATQP 240
GMQNSADLES PPKLETMVPQ DSVLRSSDRE RDGVEVLPTC SAKNLEFLEG CHPSKSNSRA 300
IPGSGTSTAS QESCQQKVEM HLPYAELPSG PPGLTTAPAN SGSWKETLDT SDAQRQPQTG 360
TSGTELQQVV CVAAASQLNG SFLLSAEAPL FTRTEETSSS ASSPTAHAAA WNSVASEEST 420
ETVSETKMSV SADLAATEQM DTGVAERKPT SDLRKTQEQP EGSLQQVPAP FLQGQNDTVQ 480
QGLLLPTFSH GISNESSVEP TDGPKAPKNT QNRVVAREES RSHGDNLEGQ QEATRALAGA 540
EPGNHDEEKS QAFHSKPHLE TKKGEVSKAH SNTENKIVPS SDSTQPLRQE VAGHRDGSHS 600
GSAEVVGQVV AESHVTDTAT SLHKLHEEDP ILSSASDGTG EHFLPQEAIW ESSRSQTKSP 660
VMLQDRGGLE AIESLPALES EKGDFLPATA AEEVPKAGEM EDILEVKKSH SPFHPPFSCD 720
GEGLLMSPGQ PCGVEKVEPG QEVHADASSP RNGKDSTIGH GLAVLSLEQD CQRKLSCPED 780
SLPPSPKNRL QPSQLDPEAS ISAILCDKNQ PPTNGQKACQ SDPGLKKQST DPSSILVPEE 840
RKPWADVSLS TQGGNEQGSE LPSKGSPCNT PSSSPKDKVL EGAPPSEMSE LSTPLGQESP 900
ALGGNEQEGT GSSSQLSEIP PPAAATALTE NLGGKDSLST GQGLSKSQQE LDDALQIGSL 960
REEARCGDSG LSEAGDVLPP PLGLDKTETA SRNRVEALPC PPDSVALLDT AHYSPDPVPT 1020
NPRVTLTQDA LESEACDEGQ KESAPQLEME QPAPLGTEAQ SPLGSFQKAE ERDGKGGSAE 1080
VNVDASEGDP GMQQASEAPE PALSSGFLQA DQSLASTLSE PRQLVQLEPS CGDALLPAGE 1140
TDGMPRSSVD VLTQHTVSGP QSLLPAEPPD TPYLHINSAA RKDAEDGSTR GAVSSEDPGA 1200
PHESPVKEPP PALENDTLEK TPAVSFTTVL QPGTADGDIS AAGDGNSIGI PQAGTTEGHV 1260
SFMPYLDRMP LPVRDEQMAR EMHVAAAPEA NARPSEIAAC PASEDAAGER EGNRERPVEL 1320
TPDLRVVASG SEGASSKQTS IIAGLPDFRE HITKIFEQSV LGALAADRPH SKKSGVPRNV 1380
LFEGPDVSLN SEKLLDGAQG VAAALLPVPP AGLQVEKKQE SAVEAESSHQ VPQDPASEKM 1440
MGLVGTALEE SRPGASVEGE RTGEPVQGTQ AHSQQARSRQ ELTVGLPSSA AVQGLPAERA 1500
PDFPVAPQSH ADVDEASAQG DKSHSIKEHL ETLPSNGQQR EDGTWDPTHT KGLTNLSGSP 1560
CALNGSSHGS VLNVPEPISE PLIPSTLEGD RQIEAAVSTA NMQNMLGNQD APKMLAGGVL 1620
TTPLDPSKMA RAAEEAEGDV TPSRAETWAC ASGDLLETGT TRMLPGVAGN SAHPGSFQDS 1680
GCSNRAQVME EDAATLQGDS QVEDQQAKQQ LGPQLPTPVG HGKPSISSPP EPDESKDEKL 1740
HLVAPEELLS DSIPGTDDVI QPAAPVDPGH PPLADSSHHG DAVSSVSTHL TVQSASPSAA 1800
RASPAPLAPE HTASAPSAAG PGVEVTPTAS PQHLAKNEPR SSDSEEAFET PESTTPVKAP 1860
PAPPPPPPEV TPEPEVIDPP APEEPGCISE PPVVVPDGPR SSESVEGSPF RPSHSSSAVF 1920
DEDKPIASSG TYNLDFDSIE LVDNFQSLEP CSADSKGQEC KVSTRRKSTE SVPPSKSTLS 1980
RSLSLQASDF DGASCPGSPE AGTLTTDACG TGSNSASSTL KRTKKTRPPS LKKKQATKKP 2040
TETPPVKETQ QEPGEESPVP SEEHLAPETK TESATPEGAG CTLSDDTPLE SPAVPTATCP 2100
LTLESAEDVS PLVSGGGRVQ NSPPVGRKSV PLTTASEAVE VTLSDSGGQE DLPAKGLSVR 2160
LEFDYSEDKG SWESQQENAP PTKKIGKKPV AKMPLRRPKM KKTPEKLDNT PASPPRSPTE 2220
PSDTPIAKGT YTFDIDKWDD PNFNPFSSTS KMQESPKLSQ QSYNFDPDAC EESLDPFKAS 2280
SKTPSSPSKS PASFEIPAST TEADGDGLNK PAKKKKTPLK TMVEDVMSVC SLFDTFRVKK 2340
SPKRSPLSDP PSQDPTPAAT PEAPSAISTV VHATDEEKLA VTSQKWTCMT VDLDADKQDF 2400
PQPSDLSNFV NETKFNSPSE GKQLGGQPDP HLALENTVPR GQRARKELDY RNSYEIEYME 2460
KLGSSLPQDD DTPKKQALYL MFDTPQESPV KSPPVRMSDS PTPCSGSSFE DTEALVNAAT 2520
KLQHPVARGL PSSQEPLLQV PEKPSQKELE AMALGTPAEA IEITAPEGAF ASADTLLSRL 2580
AHPASLCGAL GYLEPDLAEK NPPVFAQKLQ EELEFAVMRI EALKLARQIA LASRSRQDTK 2640
REAAHPPDVS ISKTALYSRI GSTEVEKPPG LLFQQPDLDS ALQVARAEVI AKEREVSEWR 2700
DKYEESRREV VEMRKIVAEY EKTIAQMIED EQREKSISHQ TVQQLVLEKE QALADLNSVE 2760
KSLADLFRRY EKMKEVLEGF RKNEEVLKKC AQEYLSRVKK EEQRYQALKV HAEEKLDRAN 2820
AEIAQVRGKA QQEQAAYQAS LRKEQLRVDA LERTLEQKNK EIEELTKICD ELIAKMGKS 2880
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR007707--TACC
PROSITE
Pfam

PF05010--TACC
Gene Ontology

GO:0005737--C:cytoplasm
GO:0015630--C:microtubule cytoskeleton
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0035257--F:nuclear hormone receptor binding
GO:0019904--F:protein domain specific binding
GO:0030953--P:astral microtubule organization
GO:0008283--P:cell proliferation
GO:0021987--P:cerebral cortex development
GO:0022027--P:interkinetic nuclear migration
GO:0000226--P:microtubule cytoskeleton organization
GO:0022008--P:neurogenesis
GO:0032886--P:regulation of microtubule-based process