dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050986
Uniprot Accession E9Q8N8; E9Q8N8_MOUSE;
Genbank Protein ID NP_001129732.1;
Genbank Nucleotide ID NM_001136260.1;
Protein Name Anion exchange protein
Protein Synonyms/Alias
Gene Name Slc4a4
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
1026KKKKKKGSLDSDNDDPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 25521595
1029KKKGSLDSDNDDEKDPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 21183079; 25521595
1060LESLGLPSPPRTPVKPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 21183079
1064GLPSPPRTPVKVVPQPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 21183079
Sequence
(Fasta)
MEDEAVLDRG ASFLKHVCDE EEVEGHHTIY IGVHVPKSYR RRRRHKRKAG HKEKKEKERI 60
SENYSDKSDV ENADESSSSI LKPLISPAAE RIRFILGEED DSPAPPQLFT ELDELLAVDG 120
QEMEWKETAR WIKFEEKVEQ GGERWSKPHV ATLSLHSLFE LRTCMEKGSI MLDREASSLP 180
QLVEMIADHQ IETGLLKPDL KDKVTYTLLR KHRHQTKKSN LRSLADIGKT VSSASRMFSN 240
PDNGSPAMTH RNLTSSSLND ISDKPEKDQL KNKFMKKLPR DAEASNVLVG EVDFLDTPFI 300
AFVRLQQAVM LGALTEVPVP TRFLFILLGP KGKAKSYHEI GRAIATLMSD EVFHDIAYKA 360
KDRHDLIAGI DEFLDEVIVL PPGEWDPTIR IEPPKSLPSS DKRKNMYSGG ENVQMNGDTP 420
HDGGHGGGGH GDCEELQRTG RFCGGLIKDI KRKAPFFASD FYDALNIQAL SAILFIYLAT 480
VTNAITFGGL LGDATDNMQG VLESFLGTAV SGAIFCLFAG QPLTILSSTG PVLVFERLLF 540
NFSKDHNFDY LEFRLWIGLW SAFMCLVLVA TDASFLVQYF TRFTEEGFSS LISFIFIYDA 600
FKKMIKLADY YPINSDFKVG YNTHFSCACL PPDPVNLSVS NDTTLAPEDL PTISSTDMYH 660
NVTFDWAYLS KKECVKYGGK LVGNNCDFVP DITLMSFILF LGTYTSSMAM KKFKTSRYFP 720
TTARKLISDF AIILSILIFC VIDALVGVDT PKLIVPSEFK PTSPNRGWFV PPFGGNPWWV 780
CLAAAIPALL VTILIFMDQQ ITAVIVNRKE HKLKKGAGYH LDLFWVAILM VVCSFMALPW 840
YVAATVISIA HIDSLKMETE TSAPGEQPKF LGVREQRVTG TLVFILTGLS VFMAPILKFI 900
PMPVLYGVFL YMGVASLNGV QFMDRLKLLL MPLKHQPDFI YLRHVPLRRV HLFTFLQVLC 960
LALLWILKST VAAIIFPVMI LALVAVRKGM DYLFSQHDLS FLDDVIPEKD KKKKEDEKKK 1020
KKKKGSLDSD NDDEKDPQHS SNATHHADKI PFLESLGLPS PPRTPVKVVP QIRIEREPED 1080
NDYLWRSKGT ETTL 1095
Keyword

KW-0181--Complete proteome
KW-0406--Ion transport
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport

Interpro

IPR013769--Band3_cytoplasmic_dom
IPR011531--HCO3_transpt_C
IPR003020--HCO3_transpt_euk
IPR003024--Na/HCO3_transpt
IPR016152--PTrfase/Anion_transptr

PROSITE
Pfam

PF07565--Band_3_cyto
PF00955--HCO3_cotransp

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0070062--C:extracellular exosome
GO:0005887--C:integral component of plasma membrane
GO:0005452--F:inorganic anion exchanger activity
GO:0008510--F:sodium:bicarbonate symporter activity
GO:0098656--P:anion transmembrane transport
GO:0015701--P:bicarbonate transport
GO:0051453--P:regulation of intracellular pH
GO:0006885--P:regulation of pH
GO:0035725--P:sodium ion transmembrane transport
GO:0006814--P:sodium ion transport