dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050982
Uniprot Accession E9Q8K6; E9Q8K6_MOUSE;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Nuclear receptor corepressor 1
Protein Synonyms/Alias
Gene Name Ncor1
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
511QQQIARPSQEEKVEEcurated23684622
Sequence
(Fasta)		MSSSGYPPNQ GAFSTEQSRY PSHSVQYTFP STRHQQEFAV PDYRSSHIEV SQASQLLQQQ 60
QQQQQLRRRP SLLSEFHPGS DRPQERRTGY EQFHSGPSPV DHDSLESKRP RLEPVSDAHF 120
QRVSAAVLPL VHSLPEGLRS SADAKKDSAF GSKHEAPSSP LAGQPCGDDQ NASPSKLSKE 180
ELIQSMDRVD REIAKVEQQI LKLKKKQQQL EEEAAKPPEP EKPVSPPPVE QKHRSIVQII 240
YDENRKKAEE AHKIFEGLGP KVELPLYNQP SDTKVYHENI KTNQVMRKKL ILFFKRRNHA 300
RKQREQKICQ RYDQLMEAWE KKVDRIENNP RRKAKESKTR EYYEKQFPEI RKQREQQERF 360
QRVGQRGAGL SATIARSEHE ISEIIDGLSE QENNEKQMRQ LSVIPPMMFD AEQRRVKFIN 420
MNGLMEDPMK VYKDRQFMNV WTDHEKEIFK DKFIQHPKNF GLIASYLERK SVPDCVLYYY 480
LTKKNENYKA LVRRNYGKRR GRNQQQIARP SQEEKVEEKE EDKAEKTEKK EEEKKDDEEK 540
DDKEDSKETT KEKDRTEATA EEPEEREQVT PRGRKTANSQ GRRKGRVTRS MTSEAAAANA 600
AAAATEEPPP PLPPPPEPIS TEPVETSRWT EEEMEVAKKG LVEHGRNWAA IAKMVGTKSE 660
AQCKNFYFNY KRRHNLDNLL QQHKQKASRK PREERDVSQC ESVASTVSAQ EDEDIEASNE 720
EENPEDSEVE AAKSSEDSSE NAASRGNTEP VAELEATTDP APCASPSSAV PTTKPAERES 780
VEAQVTDSAS A 792
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR009057--Homeodomain-like
IPR031557--N-CoR_GPS2_interact
IPR001005--SANT/Myb
IPR017884--SANT_dom
PROSITE

PS51293--SANT
Pfam

PF15784--GPS2_interact
PF00249--Myb_DNA-binding
Gene Ontology

GO:0005737--C:cytoplasm
GO:0016020--C:membrane
GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0016580--C:Sin3 complex
GO:0005876--C:spindle microtubule
GO:0005667--C:transcription factor complex
GO:0017053--C:transcriptional repressor complex
GO:0003677--F:DNA binding
GO:0042826--F:histone deacetylase binding
GO:0035033--F:histone deacetylase regulator activity
GO:0016922--F:ligand-dependent nuclear receptor binding
GO:0035257--F:nuclear hormone receptor binding
GO:0042974--F:retinoic acid receptor binding
GO:0046965--F:retinoid X receptor binding
GO:0001102--F:RNA polymerase II activating transcription factor binding
GO:0043565--F:sequence-specific DNA binding
GO:0046966--F:thyroid hormone receptor binding
GO:0003714--F:transcription corepressor activity
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0002361--P:CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:1904017--P:cellular response to Thyroglobulin triiodothyronine
GO:0042632--P:cholesterol homeostasis
GO:0032922--P:circadian regulation of gene expression
GO:0060318--P:definitive erythrocyte differentiation
GO:0046329--P:negative regulation of JNK cascade
GO:0014067--P:negative regulation of phosphatidylinositol 3-kinase signaling
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0031065--P:positive regulation of histone deacetylation
GO:0072362--P:regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter
GO:0072368--P:regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter
GO:0040014--P:regulation of multicellular organism growth
GO:0002155--P:regulation of thyroid hormone mediated signaling pathway
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0051225--P:spindle assembly
GO:0021794--P:thalamus development