dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050980
Uniprot Accession E9Q8I7; E9Q8I7_MOUSE;
Genbank Protein ID NP_598682.2; XP_011238988.1;
Genbank Nucleotide ID NM_133921.2; XM_011240686.1;
Protein Name Protein Nfxl1
Protein Synonyms/Alias
Gene Name Nfxl1
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
112KLLEEHCSSSSEEEGPhosphoSitePlus;curated22135298; 22817900; 21183079; 25338131
113LLEEHCSSSSEEEGDPhosphoSitePlus;curated22135298; 22817900; 21183079; 25338131
114LEEHCSSSSEEEGDEPhosphoSitePlus;curated22135298; 22817900; 21183079; 25338131
115EEHCSSSSEEEGDEDPhosphoSitePlus;curated22135298; 22817900; 21183079; 25338131
363VAERSCASPVWHCDQPhosphoSitePlus;curated22135298; 23684622
715CEEGCSKSRPAGCPHPhosphoSitePlus;curated22135298; 22817900; 21183079
842KEMKRKASEVKEAEAPhosphoSitePlus;curated22135298; 22817900; 21183079
Sequence
(Fasta)
MDAPWRQVAA GRGRARGRAT AVPLSGNGVP FGGAGGGRAK GSGGAVSSGP GPGGAAALAP 60
AGRGQRSAGG EAPQPPGARG EDGSELMSQK KFEEIKKSNQ AAARKLLEEH CSSSSEEEGD 120
EDLEGKQGKI VANTFTTYTT HTDGDIHELE RTKQYLNEAF QAGAMTCLIC IASVKRNQAV 180
WSCSGCFCIF HMPCIQKWAK DSQFLVSSVT DDDFGKKDYP WPCPKCRFEY KRSETPSRYY 240
CYCGKVEDPP LDPWLVPHSC GQVCEREFKP SCGHKCLLLC HPGPCPPCPK MVTTTCYCKK 300
AKPIPRRCSA KQWSCQLPCG RKLLCGHHKC ENPCHAGNCQ PCPRVSRQKC VCGKKVAERS 360
CASPVWHCDQ VCGKTLPCGN HTCEQVCHVG ACGECPRSGK RSCPCQKSKF SLPCTEDVPT 420
CGDSCDKILE CGIHRCSQRC HRGPCETCRQ EVEKQCRCGK HTKRMPCHKP YLCETKCVKM 480
RDCQKHQCRR KCCPGNCPPC DQNCGRTLGC RNHKCPSVCH RGSCYPCPET VDVKCNCGNA 540
KVTVPCGRER TTRPPKCKEL CSRPPTCHHA SQEKHRCHFG PCPPCHQPCQ KVLEKCGHLC 600
PESCHDQALV KQTGRHQPSG PWEQPAEPAF IQTALPCPPC QVPIPVECLG KHEVSPLPCH 660
AVGPYSCKRL CGRMLRCQNH TCMKECHKVT EVDSSTGKNK AGPECFHCEE GCSKSRPAGC 720
PHPCVLPCHP GKCPPCVQML RIKCHCKITS LYVECRKITT ADVSEKNLLS CCKNQCPKEL 780
PCGHRCKEMC HPGECPFNCN QKVKLRCPCK RIKRELPCNK VRENQVSVEC DATCKEMKRK 840
ASEVKEAEAN AALEEEKRRQ QAELEAFENR LKGRRKKSRK RDEVAVELSP WQKYKSYLLP 900
VCAVVVAVLM WYIFHGVD 919
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR019786--Zinc_finger_PHD-type_CS
IPR000967--Znf_NFX1
IPR001841--Znf_RING

PROSITE

PS01359--ZF_PHD_1
PS50089--ZF_RING_2

Pfam

PF01422--zf-NF-X1

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0016020--C:membrane
GO:0005634--C:nucleus
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006366--P:transcription from RNA polymerase II promoter