dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050973
Uniprot Accession E9Q863; E9Q863_MOUSE;
Genbank Protein ID XP_006508784.1;
Genbank Nucleotide ID XM_006508721.2;
Protein Name Guanine nucleotide exchange factor DBS
Protein Synonyms/Alias
Gene Name Mcf2l
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
16GAGRRFWSLSRKRRGcurated21183079
Sequence
(Fasta)		MAEKGASRGA GRRFWSLSRK RRGAPGRHKP DEIMHQDIVP LCAADIQEQL KKRFAYLSGG 60
RGQDGSPVIT FPDYPAFSEI PDKEFQNVMT YLTSIPSLQD AGIGFILVID RRQDKWTSVK 120
ASVLRIAASF PANLQLVLVL RPTGFFQRTL SDIAFKFNRD EFKMKVPVMM LSSVPELHGY 180
IDKSQLTEDL GGTLDYCHSR WLCHRTAIES FALMVKQTAQ MLQAFGTELA ETELPNDVQS 240
TSLVLSAHTE KKAKVKEDLQ LALKEGNSIL ESLREPLAES AAHSVNQDQL DNQATVQRLL 300
AQLNETEAAF DEFWAKHQQK LEQCLQLRHF EQGFREVKTT LDSMSQKIAA FTDVGNSLAH 360
VQHLLKDLTA FEEKSSVAVD KARALSLEGQ QLIENRHYAV DSIHPKCEEL QHLCDHFASE 420
VTRRRGLLSK SLELHSLLET SMKWSDEGIF LLASQPVDKC QSQDGAEAAL QEIEKFLETG 480
AENKIQELNE IYKEYECILN QDLLEHVQKV FQKQESTEEM FHRRQASLKK LAAKQTRPVQ 540
PVAPRPEALT KSPSPSPGSW RSSENSSSEG NALRRGPYRR AKSEMSEPRQ GRTSSTGEEE 600
ESLAILRRHV MNELLDTERA YVEELLCVLE GYAAEMDNPL MAHLISTGLQ NKKNILFGNM 660
EEIYHFHNRI FLRELESCID CPELVGRCFL ERMEEFQIYE KYCQNKPRSE SLWRQCSDCP 720
FFQECQKKLD HKLSLDSYLL KPVQRITKYQ LLLKEMLKYS KHCEGAEDLQ EALSSILGIL 780
KAVNDSMHLI AITGYDGNLG DLGKLLMQGS FSVWTDHKKG HTKVKELARF KPMQRHLFLH 840
EKAVLFCKKR EENGEGYEKA PSYSYKQSLN MTAVGITENV KGDTKKFEIW YNAREEVYII 900
QAPTPEIKAA WVNEIRKVLT SQLQACREAS QHRALEQSHS LPLPTPSSTS PTKGNTRNVK 960
KLEDRKTDPL SLEGYVSSSL PKPPEKGKGW SKTSHSLEAP EEDGGWSSAE ELINSSDAEE 1020
DGGVGPKKLV PGKYTVVMDD EKGGPDTLAM RSGDMVEVVE EGAEGLW 1068
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR001251--CRAL-TRIO_dom
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR018159--Spectrin/alpha-actinin
IPR002017--Spectrin_repeat
PROSITE

PS50191--CRAL_TRIO
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
Pfam

PF13716--CRAL_TRIO_2
PF00169--PH
PF00621--RhoGEF
PF00435--Spectrin
Gene Ontology

GO:0005615--C:extracellular space
GO:0005622--C:intracellular
GO:0030027--C:lamellipodium
GO:0016020--C:membrane
GO:0005545--F:1-phosphatidylinositol binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043547--P:positive regulation of GTPase activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007266--P:Rho protein signal transduction