dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050958
Uniprot Accession E9Q7P2; E9Q7P2_MOUSE;
Genbank Protein ID NP_001037773.2;
Genbank Nucleotide ID NM_001044308.2;
Protein Name Protein Cacna1i
Protein Synonyms/Alias
Gene Name Cacna1i
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 12
PositionPeptidesSourceReferences ( PMIDs )
469RQATGPGTPAPAKPGPhosphoSitePlus22135298
492CKLCPRHSPLDTTPHPhosphoSitePlus;curated22135298; 21183079
911ALESRKSSVMSLGRMPhosphoSitePlus;curated22135298; 21183079
914SRKSSVMSLGRMSYDPhosphoSitePlus;curated22135298; 21183079
948TWASRRSSWNSLKHKPHOSIDA;PhosphoSitePlus21081558; 22135298
951SRRSSWNSLKHKPPSPHOSIDA;PhosphoSitePlus21081558; 22135298
958SLKHKPPSAEHESLLPhosphoSitePlus22135298
1017RHHRRTLSLDTRDSVPhosphoSitePlus;curated22135298; 21183079
1023LSLDTRDSVDLAELVPhosphoSitePlus;curated22135298; 21183079
1745GPRMPTSSPGAPGRGPhosphoSitePlus22135298
1850VLLGDDLSLEDPTACPhosphoSitePlus22135298
1970PKIALQGSWASLRSPPhosphoSitePlus22135298
Sequence
(Fasta)
MADSNLPPSS SAAPDPEPGI TEQPGPRSPP PSPPGLEEPL DGTNPDVPHP DLAPVAFFCL 60
RQTTSPRNWC IKMVCNPWFE CVSMLVILLN CVTLGMYQPC DDMECLSDRC KILQVFDDFI 120
FIFFAMEMVL KMVALGIFGK KCYLGDTWNR LDFFIVMAGM VEYSLDLQNI NLSAIRTVRV 180
LRPLKAINRV PSMRILVNLL LDTLPMLGNV LLLCFFVFFI FGIIGVQLWA GLLRNRCFLE 240
ENFTIQGDVA LPPYYQPEED DEMPFICSLS GDNGIMGCHE IPPLKEQGRE CCLSKDDMYD 300
FGAGRQDLNA SGLCVNWNRY YNVCRTGNAN PHKGAINFDN IGYAWIVIFQ VITLEGWVEI 360
MYYVMDAHSF YNFIYFILLI IVGSFFMINL CLVVIATQFS ETKQREHRLM LEQRQRYLSS 420
STVASYAEPG DCYEEIFQYV CHILRKAKRR ALGLYQALQN RRQATGPGTP APAKPGPHAK 480
EPSHCKLCPR HSPLDTTPHT LVQPISAILA SDPSSCPRCQ HEAGRRPSGL GSTDSGQEGS 540
GSGGSAEAEA NGDGPQSSED GVSSGLGKEE EQEDGAARLC GDVWRETRAK LRGIVDSKYF 600
NRGIMMAILV NTVSMGIEHH EQPEELTNIL EICNVVFTSM FALEMILKLA AFGLFDYLRN 660
PYNIFDSIIV IISIWEIVGQ ADGGLSVLRT FRLLRVLKLV RFMPALRRQL VVLMKTMDNV 720
ATFCMLLMLF IFIFSILGMH IFGCKFSLRT DTGDTVPDRK NFDSLLWAIV TVFQILTQED 780
WNVVLYNGMA STTPWASLYF VALMTFGNYV LFNLLVAILV EGFQAEGDAN RSYSDEDQSS 840
SNLEELDKLP EGLDSSRDLK LCPIPMTPNG HLDPSLPLGG HLGPAGAMGA APRLSLQPDP 900
VLVALESRKS SVMSLGRMSY DQRSLSSSRS SYYGPWGRSG TWASRRSSWN SLKHKPPSAE 960
HESLLSGERG GSCVRACEGA REDAPPRAAP LHAPHTHHAH HGPHLAHRHR HHRRTLSLDT 1020
RDSVDLAELV PVVGAHSRAA WRAAGQAPGH EDCNGRMPNI AKDVFTKMDD RRDRGEDEEE 1080
IDYTLCFRVR KMIDVYKPDW CEVREDWSVY LFSPENKFRI LCQTIIAHKL FDYVVLAFIF 1140
LNCITIALER PQIEAGSTER IFLTVSNYIF TAIFVGEMTL KVVSLGLYFG EQAYLRSSWN 1200
VLDGFLVFVS IIDIVVSVAS AGGAKILGVL RVLRLLRTLR PLRVISRAPG LKLVVETLIS 1260
SLKPIGNIVL ICCAFFIIFG ILGVQLFKGK FYHCLGVDTR NITNRSDCVA ANYRWVHHKY 1320
NFDNLGQALM SLFVLASKDG WVNIMYNGLD AVAVDQQPVT NHNPWMLLYF ISFLLIVSFF 1380
VLNMFVGVVV ENFHKCRQHQ EAEEARRREE KRLRRLEKKR RKAQRLPYYA TYCPTRLLIH 1440
SMCTSHYLDI FITFIICLNV VTMSLEHYNQ PTSLETALKY CNYMFTTVFV LEAVLKLVAF 1500
GLRRFFKDRW NQLDLAIVLL SVMGITLEEI EINAALPINP TIIRIMRVLR IARVLKLLKM 1560
ATGMRALLDT VVQALPQVGN LGLLFMLLFF IYAALGVELF GKLVCNDENP CEGMSRHATF 1620
ENFGMAFLTL FQVSTGDNWN GIMKDTLRDC THDERSCLSS LQFVSPLYFV SFVLTAQFVL 1680
INVVVAVLMK HLDDSNKEAQ EDAEMDAEIE LEMAHGLGPG PGPCPCPCPC PCPCPCPGPR 1740
MPTSSPGAPG RGSGGAGVGG DTESHLCRHC YSPAQETLWL DSVSLIIKDS LEGELTIIDN 1800
LSGSIFHHYS SPAGCDKCHH DKQEVQLAET EAFSLNSDRS SSVLLGDDLS LEDPTACPQG 1860
PKESKGELEP PEPMQAGDLD ECFFPFAGEP VSAGPESLLC EMGAIPFNPV QSWLKHESNQ 1920
APPSPFSPDG SSPLLQMPAE FFHPAVSASQ KGQEPGMSSG TLPKIALQGS WASLRSPSVN 1980
CTLLRQATVS DTSLDASPSS SAGSLQTTLE DSLTLSDSPR RALGPPVQVP GPRASLSPAT 2040
RRRLSLRGRG LFSLRGLRAH QRSHSSGGST SPGCTYHDSM DPSDEEGRGG AGGGGAGSEH 2100
SETLSSLSLT SLFCLPPTLP PPGLTPARKF SSTSSLAAGP GRPGATVSVR GLARSPSWAA 2160
DRSKDPPGQA QLASGFGSSA PEPQPPPGES TDAASKRKR
Keyword

KW-0106--Calcium
KW-0107--Calcium channel
KW-0109--Calcium transport
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0407--Ion channel
KW-0406--Ion transport
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
KW-0851--Voltage-gated channel

Interpro

IPR030162--CACNA1I
IPR027359--Channel_four-helix_dom
IPR005821--Ion_trans_dom
IPR005445--VDCC_T_a1
IPR002077--VDCCAlpha1

PROSITE
Pfam

PF00520--Ion_trans

Gene Ontology

GO:0005886--C:plasma membrane
GO:0005891--C:voltage-gated calcium channel complex
GO:0008332--F:low voltage-gated calcium channel activity
GO:0005245--F:voltage-gated calcium channel activity
GO:0070509--P:calcium ion import
GO:0006816--P:calcium ion transport
GO:0034220--P:ion transmembrane transport
GO:0086010--P:membrane depolarization during action potential
GO:0019228--P:neuronal action potential
GO:0042391--P:regulation of membrane potential
GO:0030431--P:sleep