dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050860
Uniprot Accession E9Q474; E9Q474_MOUSE;
Genbank Protein ID XP_006541319.1;
Genbank Nucleotide ID XM_006541256.1;
Protein Name Protein Akap13
Protein Synonyms/Alias
Gene Name Akap13
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 82 (View all)
PositionPeptidesSourceReferences ( PMIDs )
345STLCCQRSPGRMAEScurated25338131
386GEEAEPASAMDSGSAPhosphoSitePlus22135298
390EPASAMDSGSASHQDPhosphoSitePlus22135298
392ASAMDSGSASHQDSCPhosphoSitePlus22135298
484KAGELEHSLLTPDATPhosphoSitePlus22135298
487ELEHSLLTPDATTQNPhosphoSitePlus22135298
578RGCEGGTTSDQSSPVPhosphoSitePlus;curated22135298; 21183079
579GCEGGTTSDQSSPVLPhosphoSitePlus;curated22135298; 21183079; 25338131
582GGTTSDQSSPVLPAAcurated25338131
583GTTSDQSSPVLPAAAPhosphoSitePlus;curated22135298; 21183079; 25338131
850SSAVELRTSMGNTSPcurated18846507
851SAVELRTSMGNTSPVcurated25338131
856RTSMGNTSPVGIGGEPhosphoSitePlus;curated22135298; 25338131
867IGGEQEGSSPTATLEPhosphoSitePlus;curated22135298; 18846507; 25338131
868GGEQEGSSPTATLEVPhosphoSitePlus;curated22135298; 25338131
870EQEGSSPTATLEVLSPhosphoSitePlus22135298
921DGKDRAMSCSSVKEDcurated25338131
924DRAMSCSSVKEDVHScurated25338131
941MSREDQRTPPSGQEIPhosphoSitePlus;curated22135298; 21183079
1077DVTVADASPATAEPRcurated25338131
Sequence
(Fasta)		MKLSPQQAPL YGDCVVTVLL AEEDKVEDDA IFYLIFSGST LYHCTSTRKV SSDTLETIAP 60
GHDCCETVKV LLCASREGLP VFVVAEEDFH FVQDEAYDAA QFLATSAGNQ QALNFTRFLD 120
RSGPPSRDVN SLDEKVALAF RHLKLPAEWN VLGTDHTLHD GGPRETLMHF AVRLGLLRLT 180
WFLLQKPGGR GALSIHNKEG ATPVSLALER GYHELHQLLT EENAGEPDSW SSLSYEIPYG 240
DCSVRHHREL DIYTLTSESE SHREPHGDSC TGHISKLMNI QQQLMKTNLK QMDNLMPLMV 300
TAQDSSCVPS VPETDGLFLP CVPEPSDHQH PPFEETKSTL CCQRSPGRMA ESSCDLSSMV 360
EEENVICSHK KNKDVGRKGE EAEPASAMDS GSASHQDSCL QSVPDCGVKG REGLPSCGNR 420
NEVTGTNYSG VATCQQPLSS RSSVLQDAMV TEPDACQHSS GRELPDSSST DVGAPEKAGE 480
LEHSLLTPDA TTQNNKPQVG EGTKERLENS DSSTTETTAV QVLSEPMEKA DITNHVFATS 540
AVGVNTPAEA SPALSSEEIP TEKPGMETQE RGCEGGTTSD QSSPVLPAAA IENKVLGGQE 600
PDTSIAGFCK TASPLDLTMP GPSSDGMPEQ NSESHARPAQ SLSGQALLCS TAEAGTPSAE 660
ATHQPSTVTS SGRLEECGSG KASLPESTMV QPSTQELCTT LCPEDPQADT VTSDTVKNTQ 720
KSVGVCHLCV SDAKNQGNGL KQDTPLTNVL EDVPRLPSVV SQTEKELAPD QVSPPASSFS 780
LASSPESESV TKDDALSLVP SQKEKGTATP QLHRTTACRD GPDGRDLSDT DKVGDGATDP 840
PPSSAVELRT SMGNTSPVGI GGEQEGSSPT ATLEVLSDSL LHNVDKAALV SDFTLPEEGV 900
SVVVPESSTA LGQDGKDRAM SCSSVKEDVH SSEMSREDQR TPPSGQEIPG LCEKPMSALC 960
AEEKAQQHTP SACLKTETKD IKEVAPQVSL LTEGGAAKSL VPPRTSLSAD SKQKASSTEQ 1020
SGSSLLPSGL PGASEALHCN QPSALDVVVE NTQFQGETNA CEVSRSAMED VTVADASPAT 1080
AEPRKKDASH CIKDIPISEL LNQEKQMTPS LPEAFLDKGV TDLQEVITPE IEPLDCKRET 1140
LEGTDLNCAT SNSKETPIEK PMQPLARDLP TETGLSVINN NVPQADMKQV AQASIPAEES 1200
NATTVSTQAA DVPTRADSIE ETATRIVEAV IRQVRASNAL MAKVETQNPS LSSPETKQLE 1260
NAYTESACAF LPGETPQIEK THEDTTGQCG AETEEPEKII LPESAPEMPD TRTGDEVDLL 1320
SRISAASEEE AVGNGAATPK MKQGPGTQAI NRESWCAIEP CPEAASLLAS KQSSECRSFI 1380
DVGLGTECAS KEGMLQRVSG SESDLFHSPS DEMDSIIFPK PEEEQLLCDT TGSSSSTDDT 1440
ASLDRHSSHG SDVSLPQTSK LNRSRNHQSA NGFFSPGVEA PESRESESEP AGSGEMEEEE 1500
MDSITEVPAN CSFLRSSMRS LSPFRRHSWG PGKNAASDAE MNQRSSMRAL GHVVRRPPIH 1560
RRSMSWCPSG VQYSAALNAD FNIRSFSLEG LTGGGVGNKP SSSLEMSSAN SSELRNPFGG 1620
EEQRNSLMSL SEEHLEPDQR QHHRMFDQQT CYRSKQQGFN YCTSAISSPL TKSISLMTIS 1680
HPGLDSSRPF HSTSANLTES ITEENCNFLP PSPSKKNFEE KSGTKVSRTF SYIRNKMSSS 1740
KKSKEKEKEK DKIKEKEKDS KEKEKDKKTL NGHTFSPIPI VGPISCSQCM KPFTNKDAYT 1800
CAGCGAFVHK GCRENLASCA KVKMKQPKGS LQAHDTSSLP TVIMRNKSSQ PKERPRSAVL 1860
LADEATAAPM FTNRRSQQSV SLSKSVSIQN ITGVGNDENM SNTWKFLSHS TDSLNKICKV 1920
NESTESLTDE GVGTDMNEGQ LMGDFESDSK QLEAESWSRT VDSKFLKQQK KDVVKRQEVI 1980
YELMQTELHH IRTLKIMSDV YSRGMMTDLL FEQQMVEKLF PCLDELISIH SQFFQRILER 2040
KKESLVDKSE KNFLIKRIGD VLVSQFSGES AERLKKTYGK FCGQHNQSVN YFKDLYTKDK 2100
RFQAFVKKKM SSSVVRRLGI PECILLVTQR ITKYPVLFQR ILQCTKDNEV EQEDLTQSLS 2160
LVKDVIGAVD SKVASYEKKV RLGEIYTKTD SKSIMRMKSG QMFAKEDLRR KKLVRDGSVF 2220
LKSTTGRLKE VQAVLLTDIL VFLQEKDQKY VFASLDHKST VISLKKLIVR EVAHEEKGLF 2280
LISMGVKDPE MVEVHASSRE ERNSWIQIIQ DTINSLNRDE DEGIPSENEE EKKLLDTKAR 2340
ELKEQLQQKD QQILLLLEEK EMIFRDMTEC STPLPEDCSP THSPRVLFRS NTEEALKGGP 2400
LMKSAINEVE ILQSLVSGSL GGTLGQSISS PVEQEVMAAP ISLPRRAETF GGFDCHQMNA 2460
SKGGEKEEGD DGQDLRRTES DSGLKKGGNG NLVFMLKRNS EQVVQSIVHL HELLSMLQGV 2520
VLQQDSYIED QKLVLTEKVL TRSASRPSSL IEQEKQRSLE KQRQDLANLQ KQQAQHLEEK 2580
RRREREWEAR EQELRDREAK LAEREETVRR RQQDLERDRE ELQQKKGTYQ CDLERLRAAQ 2640
KQLEREQEQL RRDTERLSQR QMDQNLCQVS NKHGRLMRIP SFLPNSDEFS SPSAPSVTKS 2700
GSLDSELSVS PKRNSISRTQ KDKGPFHILG SASQTKVPEG QSQAPSSTST STRLFGLSKP 2760
KEKKEKKKKS KGSRTQPGDG PASEVPAEGE EIFC 2795
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
Interpro

IPR028852--AKAP13
IPR020683--Ankyrin_rpt-contain_dom
IPR000219--DH-domain
IPR002219--PE/DAG-bd
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR018459--RII_binding_1
PROSITE

PS50010--DH_2
PS50003--PH_DOMAIN
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2
Pfam

PF16652--PH_13
PF00621--RhoGEF
PF10522--RII_binding_1
Gene Ontology

GO:0005737--C:cytoplasm
GO:0016020--C:membrane
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:1900169--P:regulation of glucocorticoid mediated signaling pathway
GO:0035023--P:regulation of Rho protein signal transduction