dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050857
Uniprot Accession E9Q447; E9Q447_MOUSE;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Spectrin alpha chain, non-erythrocytic 1
Protein Synonyms/Alias
Gene Name Sptan1
Gene Synonyms/Alias Spna2;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
1055QIDNQYQSLLELGEKPhosphoSitePlus22135298
Sequence
(Fasta)
MDPSGVKVLE TAEDIQERRQ QVLDRYHRFK ELSTLRRQKL EDSYRFQFFQ RDAEELEKWI 60
QEKLQVASDE NYKDPTNLQG KLQKHQAFEA EVQANSGAIV KLDETGNLMI SEGHFASETI 120
RTRLMELHRQ WELLLEKMRE KGIKLLQAQK LVQYLRECED VMDWINDKEA IVTSEELGQD 180
LEHVEVLQKK FEEFQTDLAA HEERVNEVSQ FAAKLIQEQH PEEELIKTKQ DEVNAAWQRL 240
KGLALQRQGK LFGAAEVQRF NRDVDETIGW IKEKEQLMAS DDFGRDLASV QALLRKHEGL 300
ERDLAALEDK VKALCAEADR LQQSHPLSAS QIQVKREELI TNWEQIRTLA AERHARLDDS 360
YRLQRFLADF RDLTSWVTEM KALINADELA NDVAGAEALL DRHQEHKGEI DAHEDSFKSA 420
DESGQALLAA SHYASDEVRE KLSILSEERT ALLELWELRR QQYEQCMDLQ LFYRDTEQVD 480
NWMSKQEAFL LNEDLGDSLD SVEALLKKHE DFEKSLSAQE EKITALDEFA TKLIQNNHYA 540
MEDVATRRDA LLSRRNALHE RAMHRRAQLA DSFHLQQFFR DSDELKSWVN EKMKTATDEA 600
YKDPSNLQGK VQKHQAFEAE LSANQSRIDA LEKAGQKLID VNHYAKEEVA ARMNEVISLW 660
KKLLEATELK GIKLREANQQ QQFNRNVEDI ELWLYEVEGH LASDDYGKDL TNVQNLQKKH 720
ALLEADVAAH QDRIDGITIQ ARQFQDAGHF DAENIKKKQE ALVARYEALK EPMVARKQKL 780
ADSLRLQQLF RDVEDEETWI REKEPIAAST NRGKDLIGVQ NLLKKHQALQ AEIAGHEPRI 840
KAVTQKGNAM VEEGHFAAED VKAKLSELNQ KWEALKAKAS QRRQDLEDSL QAQQYFADAN 900
EAESWMREKE PIVGSTDYGK DEDSAEALLK KHEALMSDLS AYGSSIQALR EQAQSCRQQV 960
APMDDETGKE LVLALYDYQE KSPREVTMKK GDILTLLNST NKDWWKVEVN DRQGFVPAAY 1020
VKKLDPAQSA SRENLLEEQG SIALRQGQID NQYQSLLELG EKRKGMLEKS CKKFMLFREA 1080
NELQQWITEK EAALTNEEVG ADLEQVEVLQ KKFDDFQKDL KANESRLKDI NKVAEDLESE 1140
GLMAEEVQAV QQQEVYGAMP RDEADSKTAS PWKSARLMVH TVATFNSIKE LNERWRSLQQ 1200
LAEERSQLLG SAHEVQRFHR DADETKEWIE EKNQALNTDN YGHDLASVQA LQRKHEGFER 1260
DLAALGDKVN SLGETAQRLI QSHPESAEDL KEKCTELNQA WTSLGKRADQ RKAKLGDSHD 1320
LQRFLSDFRD LMSWINGIRG LVSSDELAKD VTGAEALLER HQEHRTEIDA RAGTFQAFEQ 1380
FGQQLLAHGH YASPEIKEKL DILDQERTDL EKAWVQRRMM LDHCLELQLF HRDCEQAENW 1440
MAAREAFLNT EDKGDSLDSV EALIKKHEDF DKAINVQEEK IAALQAFADQ LIAVDHYAKG 1500
DIANRRNEVL DRWRRLKAQM IEKRSKLGES QTLQQFSRDV DEIEAWISEK LQTASDESYK 1560
DPTNIQLSKL LSKHQKHQAF EAELHANADR IRGVIDMGNS LIERGACAGS EDAVKARLAA 1620
LADQWQFLVQ KSAEKSQKLK EANKQQNFNT GIKDFDFWLS EVEALLASED YGKDLASVNN 1680
LLKKHQLLEA DISAHEDRLK DLNSQADSLM TSSAFDTSQV KEKRDTINGR FQKIKSMATS 1740
RRAKLSESHR LHQFFRDMDD EESWIKEKKL LVSSEDYGRD LTGVQNLRKK HKRLEAELAA 1800
HEPAIQGVLD TGKKLSDDNT IGQEEIQQRL AQFVEHWKEL KQLAAARGQR LEESLEYQQF 1860
VANVEEEEAW INEKMTLVAS EDYGDTLAAI QGLLKKHEAF ETDFTVHKDR VNDVCTNGQD 1920
LIKKNNHHEE NISSKMKGLN GKVSDLEKAA AQRKAKLDEN SAFLQFNWKA DVVESWIGEK 1980
ENSLKTDDYG RDLSSVQTLL TKQETFDAGL QAFQQEGIAN ITALKDQLLA AKHIQSKAIE 2040
ARHASLMKRW TQLLANSATR KKKLLEAQSH FRKVEDLFLT FAKKASAFNS WFENAEEDLT 2100
DPVRCNSLEE IKALREAHDA FRSSLSSAQA DFNQLAELDR QIKSFRVASN PYTWFTMEAL 2160
EETWRNLQKI IKERELELQK EQRRQEENDK LRQEFAQHAN AFHQWIQETR TYLLDGIAYR 2220
RVIRVCQYEV GDDLSGRSCM VEESGTLESQ LEATKRKHQE IRAMRSQLKK IEDLGAAMEE 2280
ALILDNKYTE HSTVGLAQQW DQLDQLGMRM QHNLEQQIQA RNTTGVTEEA LKEFSMMFKH 2340
FDKDKSGRLN HQEFKSCLRS LGYDLPMVEE GEPDPEFEAI LDTVDPNRDG HVSLQEYMAF 2400
MISRETENVK SSEEIESAFR ALSSEGKPYV TKEELYQNLT REQADYCVSH MKPYVDGKGR 2460
ELPTAFDYVE FTRSLFVN 2479
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain

Interpro

IPR011992--EF-hand-dom_pair
IPR014837--EF-hand_Ca_insen
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR001452--SH3_domain
IPR018159--Spectrin/alpha-actinin
IPR013315--Spectrin_alpha_SH3
IPR002017--Spectrin_repeat

PROSITE

PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50002--SH3

Pfam

PF13499--EF-hand_7
PF08726--EFhand_Ca_insen
PF00018--SH3_1
PF00435--Spectrin

Gene Ontology

GO:0030863--C:cortical cytoskeleton
GO:0032437--C:cuticular plate
GO:0070062--C:extracellular exosome
GO:1903561--C:extracellular vesicle
GO:0005916--C:fascia adherens
GO:0043231--C:intracellular membrane-bounded organelle
GO:0016328--C:lateral plasma membrane
GO:0016020--C:membrane
GO:0015630--C:microtubule cytoskeleton
GO:0030018--C:Z disc
GO:0005509--F:calcium ion binding
GO:0046982--F:protein heterodimerization activity
GO:0030507--F:spectrin binding