dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050855
Uniprot Accession E9Q440; E9Q440_MOUSE;
Genbank Protein ID NP_780465.4;
Genbank Nucleotide ID NM_175256.5;
Protein Name Protein HEG homolog 1
Protein Synonyms/Alias
Gene Name Heg1
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
225TLRSLDLSSAATRPAPhosphoSitePlus;curated22135298; 21183079
226LRSLDLSSAATRPARPhosphoSitePlus22135298
229LDLSSAATRPARPTPPhosphoSitePlus;curated22135298; 21183079
235ATRPARPTPRGNVTEPhosphoSitePlus;curated22135298; 21183079
Sequence
(Fasta)
MATPRAPRWP PPSLLLLLLL PLLLLPPAAP GARGSLPSPA HRTLLPVAGP LSPPGAGHTA 60
PGPGVATRRG RSGRVPRGVS AALESLPESP SSSRSQRRIT PSQTESGTSL GFLERTRELP 120
EEGTVHTQVA GTWVSRQASH PALEPGEPTV LSQKRNSSGQ EHSGPPFSWS QSHPPPSDHP 180
SSPEDGAMLS DSSDLADSTS GARTPHTSAM STRSGERTLR SLDLSSAATR PARPTPRGNV 240
TEHAGLLSGA PTLGVTGLSY TREHGSDAGQ RTSSDHTDHG YVPSTFTKGE RTLLSITDNT 300
SYSEASESST SSVKISDSPS QAQPKQSSMS SDDDEPAQSS TESPVLHTSN LPTYTSTVNM 360
PNTLVLDTGT KPVEDPSDSR VPSTQPSPSQ PQPFSSALPS TRSPGSTSET TTSSPSPSPI 420
SLLVSTLAPY SVSQTTFPHP SSTLVPHRPR EPRVTSVQMS TAISAIALIP SNQTANPKNQ 480
STPQQEKPIT EAKSPSLVSP PTDSTKAVTV SLPPGAPWSP ALTGFSTGPA LPATSTSLAQ 540
MSPALTSAMP QTTHSPVTSP STLSHVEALT SGAVVVHTTP KKPHLPTNPE ILVPHISTEG 600
AITTEGNREH TDPTTQPIPL TTSTTSAGER TTELGRAEES SPSHFLTPSS PQTTDVSTAE 660
MLTSRYITFA AQSTSQSPTA LPPLTPVNSC TVNPCLHDGK CIVDLTGRGY RCVCPPAWQG 720
ENCSVDVNEC LSSPCPPLAT CNNTQGSFTC RCPVGYQLEK GICNLVRTFV TEFKLKKTFL 780
NTTAENHSNT QELENEIAQT LNVCFSTLPG YIRTTAHVSR EPSTVFISLK TTFALASNVT 840
LFDLADRIQK YVNSCRSSAE VCQLLGSQRR VFRAGSLCKR KSPECDKETS ICTDLDGVAL 900
CQCKSGYFQF NKMDHSCRAC EDGYRLENET CMSCPFGLGG LNCGNPYQLI TVVIAAAGGG 960
LLLILGVALI VTCCRKSKND ISKLIFKSGD FQMSPYTDVP KNPRSQEWGR EAIEMHENGS 1020
TKNLLQMTDV YYSPTNVRNP ELERNGLYPA YTGLPGSRHS CIFPGQYNPS FISDESRRRD 1080
YF 1083
Keyword

KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0245--EGF-like domain
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001881--EGF-like_Ca-bd_dom
IPR013032--EGF-like_CS
IPR000742--EGF-like_dom
IPR000152--EGF-type_Asp/Asn_hydroxyl_site
IPR018097--EGF_Ca-bd_CS
IPR028720--HEG

PROSITE

PS00010--ASX_HYDROXYL
PS00022--EGF_1
PS01186--EGF_2
PS50026--EGF_3
PS01187--EGF_CA

Pfam

PF00008--EGF
PF07645--EGF_CA

Gene Ontology

GO:0009986--C:cell surface
GO:0005911--C:cell-cell junction
GO:0009897--C:external side of plasma membrane
GO:0016021--C:integral component of membrane
GO:0005509--F:calcium ion binding
GO:0003209--P:cardiac atrium morphogenesis
GO:0055017--P:cardiac muscle tissue growth
GO:0007043--P:cell-cell junction assembly
GO:0045216--P:cell-cell junction organization
GO:0001885--P:endothelial cell development
GO:0001886--P:endothelial cell morphogenesis
GO:0007507--P:heart development
GO:0001701--P:in utero embryonic development
GO:0030324--P:lung development
GO:0003017--P:lymph circulation
GO:0001945--P:lymph vessel development
GO:0035264--P:multicellular organism growth
GO:0060039--P:pericardium development
GO:0090271--P:positive regulation of fibroblast growth factor production
GO:0009791--P:post-embryonic development
GO:0050878--P:regulation of body fluid levels
GO:0001944--P:vasculature development
GO:0001570--P:vasculogenesis
GO:0048845--P:venous blood vessel morphogenesis
GO:0003281--P:ventricular septum development
GO:0003222--P:ventricular trabecula myocardium morphogenesis