dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050847
Uniprot Accession E9Q3S4; M3K19_MOUSE;
Genbank Protein ID NP_035867.1;
Genbank Nucleotide ID NM_011737.1;
Protein Name Mitogen-activated protein kinase kinase kinase 19
Protein Synonyms/Alias SPS1/STE20-related protein kinase YSK4;
Gene Name Map3k19
Gene Synonyms/Alias Ysk4;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
648DMFKEINSASNGPGIPhosphoSitePlus22135298
650FKEINSASNGPGIYEPhosphoSitePlus22135298
Sequence
(Fasta)		MDSMPRPERH AESLLDICHE AGSTPMEMTV SQTENLTLQS ISSSEDFDLE DDFSPFILAR 60
EGAAPRGENW PRRTEGVEII VTFPPDPLQE ASQEDLKESN QVTSEHQERE QVHPVSPPDD 120
AEMVGLTGRM LTTQPSLLKT DGSSEELCGV DVALSPPRPC LDSSLAASAA GEVAPCVLKE 180
QQRQSDEFPT SDISYSSRRT GLPLPPLSCL PMRSCIFNME KSPKSPRHRE RKVPSLSLSV 240
PKLLEPLSRP LSQSAEFSSS KNHQEVTQEG PVEHTLRGSN CTLWSRNMCS FRKSGKQGVA 300
ESWPSQEMEG WDKTKTSGFK EGPSLFSCES VKEDTTPTER ERDSGYHVSE MQRGGEDSQY 360
LSSRKKESWT ARVVERDSGV EHPILCKLLE VSNSEMTPAE EKEIGNENVP DAKSNSVHKS 420
GAMEPHAASE EVSVPKNGPS VNSDGPAEEL EGHRDIEQNR KIPMEEETNP EMNGVVPLTH 480
IAFPGEGTSK GPARAEPHLQ RRKRPAQNSN SFNLLAHREH DKLQTNTHRT KLDSRTKARN 540
RAPPNLMVSI QASIKPNMHK NSIKTQVFPA LELIDHRPHP SSKFQRRAPL TEKKSTHQTQ 600
KPKKQAFPRI GKHAGIKKPG IPLSAETTDP RLHFLDLKYS DMFKEINSAS NGPGIYEMFG 660
TPVYCHIREA ERHDHRCYRE IRTAPSGRCV VNKCQSSESD RCSNSRARLL QKRQHIKPPK 720
PLHGLRQKHR GFISKDKGCK DMGGHTEDSV SEPDGQMKSP GNDFLSSKDD AQLMHLIPIP 780
ELSPEQKAPA PVSDLSIVEE IFTEECADEE GILNDDSLTQ SLGDLKEPEG LHPQAPLVPS 840
ENSWAVLSEK RSGKRVSPEK HNVEPLDKIN AEQMFPGYLE FDSLSEKSKT LVSFSSCSFQ 900
ENLERAPSPT EQHWARSLEQ DSLENNSTTY QTFGKISQEI LDPGKNEELT DELLGCLVEE 960
LLALDEKDNN SCQIMTNEAD AKNLNLVFSR RGNTIEELGR ETTDVKLQRC INGFRIYDEE 1020
NFLTSNEKKT LSDKSLNHEE AIFWTKGEIL GRGAYGTVYC GLTSLGQLIA VKQVALDTSD 1080
KLATEKEYRK LQEEVDLLKA LKHVNIVAYL GTCLEENTLS IFMEFVPGGS ISSIINRFGP 1140
LPEMVFCKYT RQILQGVAYL HDNCVVHRDI KGNNVMLMPT GIIKLIDFGC AKRLAWAGLN 1200
GTHSDMLKSM RGTPYWMAPE VINESGYGRK SDIWSIGCTV FEMATGKPPL ASMDRMAAMF 1260
YIGAHRGLMP PLPARFSEPA ADFVRLCLTR DQHERPSALQ LLKHSFLKRS Q 1312
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF00069--Pkinase
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000186--P:activation of MAPKK activity
GO:0032147--P:activation of protein kinase activity
GO:0042981--P:regulation of apoptotic process
GO:0007346--P:regulation of mitotic cell cycle
GO:0051403--P:stress-activated MAPK cascade