dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050845
Uniprot Accession E9Q3P4; E9Q3P4_MOUSE;
Genbank Protein ID NP_001074832.2;
Genbank Nucleotide ID NM_001081363.2;
Protein Name Protein Cenpf
Protein Synonyms/Alias
Gene Name Cenpf
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 23 (View all)
PositionPeptidesSourceReferences ( PMIDs )
224ENTPSRLSSDALKTPPhosphoSitePlus22135298
225NTPSRLSSDALKTPLPhosphoSitePlus22135298
237TPLRRDGSAAHFLGEPhosphoSitePlus;curated22135298; 21183079
247HFLGEEVSPNKSSMKPHOSIDA;PhosphoSitePlus;SysPTM 2.0;curated21081558; 22135298; 18846507; 19366988; 21183079; 25338131
252EVSPNKSSMKTGRGDPhosphoSitePlus22135298
318LQLQLEKTKVELIEKPhosphoSitePlus22135298
761TLRDLLKSRGSSLVTPhosphoSitePlus22135298
764DLLKSRGSSLVTNEDPhosphoSitePlus22135298
776NEDNQRSSEDNQRSSPhosphoSitePlus22135298
827CSVDGGRSPEHIAILPhosphoSitePlus;curated22135298; 21743459; 21183079; 25338131
874GEVEENLSKAEQIHQPhosphoSitePlus22135298
1051DLRGNYKTAQENNAKPhosphoSitePlus22135298
1172LTQTKHDSYLAVEPVcurated25338131
1334DSRTECITATSQMTAcurated25338131
1652QLQELDLSSRSLLGTcurated25338131
1655ELDLSSRSLLGTDLEPhosphoSitePlus;curated22135298; 21183079; 25338131
1659SSRSLLGTDLESVVRPhosphoSitePlus22135298
1688ISETTEKTPKQDTDQPhosphoSitePlus22135298
1824QLKMKIATCIQLEKIPhosphoSitePlus22135298
2818ASGKRQRSSGIWEHGcurated25338131
Sequence
(Fasta)		MSWALEEWKE GLPSRALQKI QELEGQLEKL KKEKQQRQFQ LDSLEAALQK QKQKVEDGKT 60
EGADLKRENQ RLMEICEHLE KSRQKLSHEL QVKESQVNLQ ESQLSSCKKQ IEKLEQELKR 120
CKSEFERSQQ VAQSADVSLN PCSTPQKLFA TPLTPSSTYE DLKEKYNKEV EERKRLEEEV 180
KALHAKKVSL PVSQATMNHR DIARHQASSS VFPWQQENTP SRLSSDALKT PLRRDGSAAH 240
FLGEEVSPNK SSMKTGRGDC SSLPGEPHSA QLLHQAKAQN QDLKSKMTEL ELRLQGQEKE 300
MRSQVNKCQD LQLQLEKTKV ELIEKERILN KTRDEVVRST AQYDQAAAKC TTLEQKLKTL 360
TEELSCHRQN AESAKRSLEQ RIKEKEKELQ EELSRQHQSF QALDSEYTQM KTRLTQELQQ 420
VKHLHSTLQL ELEKVTSVKQ QLERNLEEIR LKLSRAEQAL QASQVAENEL RRSSEEMKKE 480
NSLIRSQSEQ RTREVCHLEE ELGKVKVSLS KSQNFAEEMK AKNTSQEIML RDLQEKLNQQ 540
ENSLTLEKLK LALADLERQR NCSQDLLKKR EHHIDQLNNK LNKIEKEFET LLSALELKKK 600
ECEELKEEKN QISFWKIDSE KLINQIESEK EILLGKINHL ETSLKTQQVS PDSNERIRTL 660
EMERENFTVE IKNLQSMLDS KMVEIKTQKQ AYLELQQKSE SSDQKHQKEI ENMCLKANKL 720
TGQVESLECK LQLLSSEVVT KDQQYQDLRM EYETLRDLLK SRGSSLVTNE DNQRSSEDNQ 780
RSSEDNQRGS LAFEQQPAVS DSFANVMGRK GSINSERSDC SVDGGRSPEH IAILQNRVTS 840
LESSLESQNQ MNSDLQMRCE ELLQIKGEVE ENLSKAEQIH QNFVAETNQC ISKLQEDAAV 900
HQNIVAETLA TLESKEKELQ LLKEKLEAQQ TEVQKLNKNN CLLEGTLKEL QLLSDTLSSE 960
KKEMNSIISL SKKNIEELTQ ANEALKEVNE ALEQEKMNLL QKHEKITSCI AEQERSIAEL 1020
SDQYKQERLQ LLQRCEETEA VLEDLRGNYK TAQENNAKLE CMLSECTALC ENRKNELEQL 1080
KETFAKEQQE FLTKLAFAEE QNRKLMLELE IEQQTVRSEI TNTNKHSMSA TDGLRQECLT 1140
LNEEQNEQQN EVSNLTHENE QLMELTQTKH DSYLAVEPVE NSVKATEDEI GKSSSQYQMD 1200
IDTKDISLDS YKAQLVHLEA LVRILEVQLD QSEEENKKLH LELQTIREEL ETKSSQDPQS 1260
QARTGLKDCD TAEEKYVSML QELSASQNEN AHLQCSLQTA VNKLNELGKM CDVLRVEKLQ 1320
LESELNDSRT ECITATSQMT AEVEKLVSEM KMLNHESALS QNELMKDTSG GEFHDKANHS 1380
SVFLTPLDSS NFCEQMTLSS KEVRVHFAEL QEKFSCLQSE HKILHDQHCE VSSKMSALRS 1440
YVDTLKAENS ALSMSLRTLQ GDLVKEGEPA AEGGHGLPLS FCGADSPSLT NFGETSFYKD 1500
VLEQTGDTCH LSLEGNASAN SCDLDEEFSS SLEEETLTEK ESPPAPGRTV EGLEVLCQVY 1560
LQSLKNLEEK TESQRIMKNK EIEKLEQLLS SERKELSCLR KQYLSEKEQW QQKLTSVTLE 1620
MESKLAEEKQ QTKTLSLELE VARLQLQELD LSSRSLLGTD LESVVRCQND NYDIKESEVY 1680
ISETTEKTPK QDTDQTCDKD IQQDLGLETS VTESETTRLT GEGCEEQPPK TNCEAPAEDK 1740
TQDCSECISE LCSSSNVLVP MDVLEDQGSI QNLQLQKDTL NENLRLLPEV EDWDKKVESL 1800
LNEIMEADSK LSLQEVQLKM KIATCIQLEK IVKDLRKEKA DLSEKLESLP CNQEVCLRVE 1860
RSEEDLGFNL DMGANELLSK STKDNATNTE DNYKEKFLDM ERELTRIKSE KANIEHHILS 1920
VETNLEVVQA EKLCLERDTE SKQKVIIDLK EELFTVISER NRLREELDNV SKESKALDQM 1980
SKKMKEKIEE LESHQRESLR HIGAVESEVK DKADLIQTLS FNVGELTKDK AHLQEQLQNL 2040
QNDSQELSLA IGELEIQIGQ LNKEKESLVK ESQNFQIKLT ESECEKQTIS KALEVALKEK 2100
GEFAVQLSSA QEEVHQLRRG IEKLSVRIEA DEKKHLSAVA KLKESQRESD SLKDTVETLE 2160
RELERSEENQ ELAILDSENL KAEVETLKAQ KDEMTKSLRI FELDLVTVRT ERENLAKQLQ 2220
EKQSRVSELD ERCSSLRRLL EEKEQARVQM EEDSKSAMLM LQMQLKELRE EVAALCNDQE 2280
TLKAQEQSLD QPGEEVHHLK SSIRKLKVHI DADEKKHQNI LEQLKESKHH ADLLKDRVEN 2340
LEQELILSEK NMIFQAEKSK AEIQTLKSEI QRMAQNLQDL QLELISTRSE NENLMKELKK 2400
EQERVSDLET INSSIENLLK DKEQEKVQMK EEAKITVEML QTQLKELNET VVSLCNDQEV 2460
SKTKEQNLGS QVQTLELEKA QLLQDLGEAK NKYIIFQSSV NALTQEVEAG KQKLEKGEKE 2520
IRTLKEQLKS QEQLVCKLAQ VEGEQQLWQK QKLELRNVTM ALEQKVQVLQ SENNTLQSTY 2580
EALQNSHKSL ESELGLIKLE KVALVERVST ISGKEAELQR ELRDMLQKTT QLSEDYNKEK 2640
NRLTEEVEVL REELQNTKAA HLKSVNQLEK ELQRAQGKIK LMLKSCRQLE GEKEMLQKEL 2700
SQLEAAQQQR AGSLVDSNVD EVMTENKALK ETLEEKVKEA DKYLDKYCSL LISHEELEKA 2760
KEILEIEVAR LKSRQSRQDL QSSPLLNSSI PGPSPNTSVS EMKSASGQNK ASGKRQRSSG 2820
IWEHGKRAAP STAETFSKKS RKSDSKSTRP AEHEQETEFE PEGLPEVVKK GFADIPTGKT 2880
SPYILRRTTM ATRTSPRFAT QKLVGSSPSL GKENVVESSK PTAGGSRSQK VKVVQESSAD 2940
SHTAFQELPA KSLTASNIPG RNSTESPREG LRAKRAYPAS SPAAGPDPTN NENCRVQ 2998
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR018302--CenpF/LEK1_Rb-prot-bd
IPR019513--Centromere_CenpF_leu-rich_rpt
IPR018463--Centromere_CenpF_N
PROSITE
Pfam

PF10490--CENP-F_C_Rb_bdg
PF10473--CENP-F_leu_zip
PF10481--CENP-F_N
Gene Ontology

GO:0000775--C:chromosome, centromeric region
GO:0000940--C:condensed chromosome outer kinetochore
GO:0005737--C:cytoplasm
GO:0030496--C:midbody
GO:0005635--C:nuclear envelope
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0045120--C:pronucleus
GO:0005819--C:spindle
GO:0000922--C:spindle pole
GO:0045502--F:dynein binding
GO:0008022--F:protein C-terminus binding
GO:0042803--F:protein homodimerization activity
GO:0008134--F:transcription factor binding
GO:0007059--P:chromosome segregation
GO:0051310--P:metaphase plate congression
GO:0000278--P:mitotic cell cycle
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0015031--P:protein transport
GO:0010389--P:regulation of G2/M transition of mitotic cell cycle
GO:0016202--P:regulation of striated muscle tissue development