dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050843
Uniprot Accession E9Q3M5; E9Q3M5_MOUSE;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Anion exchange protein
Protein Synonyms/Alias
Gene Name Slc4a5
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
226TKKPIHRSLADIGKSPhosphoPep 2.0;PhosphoSitePlus;curated19060867; 22135298; 21743459
276LCHAQSRSMNDISHTPhosphoSitePlus;curated22135298; 21183079
327AFVRLVQSAMLGGVTPhosphoSitePlus22135298
340VTEVPVPTRFLFILLPhosphoSitePlus22135298
1084MPQFLPPSVVKIPMEPHOSIDA;PhosphoSitePlus21081558; 22135298
Sequence
(Fasta)
MKVDEEKAGV KKLDPTSYKR RQPEQDFPSI HIGFPVPSYS QRKSDSKGHL SGLQKVQWSL 60
KPGKPQQELA GPGIRASSQG GAVDFTKRTR SPAAEQLQDI LGEEDEAPNP TLFTEMDTLQ 120
HDGDQMEWKE SARWIKFEEK VEEGGERWSK PHVSTLSLHS LFELRTCLQT GTVLLDLDSC 180
SLPQIIDDVI EKQIEDGLLR PELRERVSYV LLRKHRHQTK KPIHRSLADI GKSVSTTNRS 240
SARSSSAGPT LHRSTEDLRI RQSTSYGHLC HAQSRSMNDI SHTPNTDQRK NKFMKKIPKD 300
SEASNVLVGE VDFLDQPFIA FVRLVQSAML GGVTEVPVPT RFLFILLGPS GRAKSYNEIG 360
RAIATLMVDD LFSDVAYKAR NREDLIAGID EFLDEVIVLP PGEWDPNIRI EPPKKVPSAD 420
KRKSVFSLAE PGQMNGSVGG GGASAGGGGS GGGAGGSGAG GVGSGDEAEM PAMHEIGEEL 480
IWTGRFFGGL CLDVKRKLPW FPSDFYDGFH LQSISAVLFI YLGCITNAIT FGGLLGDATD 540
NYQGVMESFL GTAMAGSLFC LFSGQPLIIL SSTGPILIFE KLLFDFSKAN GLDYMEFRLW 600
IGLHSAIQCL ILVATDASFI IKYITRFTEE GFSTLISFIF IYDAIKKMIG AFKYYPINTD 660
FKPDFITTYK CECVAPDTVN TTTVNASAPL APNTNTSLYT PLNLTALDWS LLSKKECLSY 720
GGRLLGSSCQ FVPDLALMSF ILFFGTYSMT LTLKKFKFSR YFPTKVRTLV ADFSIVFSIL 780
LFCGIDACFG LQTPKLHVPS VIKPTRPDRG WFVAPFGKNP WWVYPASILP ALLVTILIFM 840
DQQITAVIVN RKENKLRKAA GYHLDLFWVG ILMALCSFTG LPWYVAATVI SIAHIDSLKM 900
ETETSAPGEQ PQFLGVREQR VTGVMVFILT GISVFLAPIL KYIPMPVLYG VFLYMGVASL 960
NGIQFWERCK LFLMPAKHQP DHAFLRHVPL RRIHLFTLVQ ILCLALLWIL KSTMAAIIFP 1020
VMILGLIIVR RLLDLIFSQH DLAWIDNILP EKDKKETDKK KKRRKEVHET AEKEVAMPQF 1080
LPPSVVKIPM EGIPSDPQNG IHCVARKRSS SWSYSL 1117
Keyword

KW-0181--Complete proteome
KW-0406--Ion transport
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport

Interpro

IPR013769--Band3_cytoplasmic_dom
IPR011531--HCO3_transpt_C
IPR003020--HCO3_transpt_euk
IPR003024--Na/HCO3_transpt
IPR016152--PTrfase/Anion_transptr

PROSITE
Pfam

PF07565--Band_3_cyto
PF00955--HCO3_cotransp

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0005452--F:inorganic anion exchanger activity
GO:0008510--F:sodium:bicarbonate symporter activity
GO:0098656--P:anion transmembrane transport
GO:0015701--P:bicarbonate transport
GO:0033326--P:cerebrospinal fluid secretion
GO:0002064--P:epithelial cell development
GO:0006811--P:ion transport
GO:0048311--P:mitochondrion distribution
GO:0010468--P:regulation of gene expression
GO:0051453--P:regulation of intracellular pH
GO:0003073--P:regulation of systemic arterial blood pressure
GO:0003014--P:renal system process
GO:0060041--P:retina development in camera-type eye
GO:0035725--P:sodium ion transmembrane transport