dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050829
Uniprot Accession E9Q394; E9Q394_MOUSE;
Genbank Protein ID NP_083608.1;
Genbank Nucleotide ID NM_029332.1;
Protein Name Protein Akap13
Protein Synonyms/Alias
Gene Name Akap13
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
1569PIHRRSFSLEGLTGGPhosphoSitePlus22135298
Sequence
(Fasta)
MKLSPQQAPL YGDCVVTVLL AEEDKVEDDA IFYLIFSGST LYHCTSTRKV SSDTLETIAP 60
GHDCCETVKV LLCASREGLP VFVVAEEDFH FVQDEAYDAA QFLATSAGNQ QALNFTRFLD 120
RSGPPSRDVN SLDEKVALAF RHLKLPAEWN VLGTDHTLHD GGPRETLMHF AVRLGLLRLT 180
WFLLQKPGGR GALSIHNKEG ATPVSLALER GYHELHQLLT EENAGEPDSW SSLSYEIPYG 240
DCSVRHHREL DIYTLTSESE SHREPHGDSC TGHISKLMNI QQQLMKTNLK QMDNLMPLMV 300
TAQDSSCVPS VPETDGLFLP CVPEPSDHQH PPFEETKSTL CCQRSPGRMA ESSCDLSSMV 360
EEENVICSHK KNKDVGRKGE EAEPASAMDS GSASHQDSCL QSVPDCGVKG REGLPSCGNR 420
NEVTGTNYSG VATCQQPLSS RSSVLQDAMV TEPDACQHSS GRELPDSSST DVGAPEKAGE 480
LEHSLLTPDA TTQNNKPQVG EGTKERLENS DSSTTETTAV QVLSEPMEKA DITNHVFATS 540
AVGVNTPAEA SPALSSEEIP TEKPGMETQE RGCEGGTTSD QSSPVLPAAA IENKVLGGQE 600
PDTSIAGFCK TASPLDLTMP GPSSDGMPEQ NSESHARPAQ SLSGQALLCS TAEAGTPSAE 660
ATHQPSTVTS SGRLEECGSG KASLPESTMV QPSTQELCTT LCPEDPQADT VTSDTVKNTQ 720
KSVGVCHLCV SDAKNQGNGL KQDTPLTNVL EDVPRLPSVV SQTEKELAPD QVSPPASSFS 780
LASSPESESV TKDDALSLVP SQKEKGTATP QLHRTTACRD GPDGRDLSDT DKVGDGATDP 840
PPSSAVELRT SMGNTSPVGI GGEQEGSSPT ATLEVLSDSL LHNVDKAALV SDFTLPEEGV 900
SVVVPESSTA LGQDGKDRAM SCSSVKEDVH SSEMSREDQR TPPSGQEIPG LCEKPMSALC 960
AEEKAQQHTP SACLKTETKD IKEVAPQVSL LTEGGAAKSL VPPRTSLSAD SKQKASSTEQ 1020
SGSSLLPSGL PGASEALHCN QPSALDVVVE NTQFQGETNA CEVSRSAMED VTVADASPAT 1080
AEPRKKDASH CIKDIPISEL LNQEKQMTPS LPEAFLDKGV TDLQEVITPE IEPLDCKRET 1140
LEGTDLNCAT SNSKETPIEK PMQPLARDLP TETGLSVINN NVPQADMKQV AQASIPAEES 1200
NATTVSTQAA DVPTRADSIE ETATRIVEAV IRQVRASNAL MAKVETQNPS LSSPETKQLE 1260
NAYTESACAF LPGETPQIEK THEDTTGQCG AETEEPEKII LPESAPGKQG KMPDTRTGDE 1320
VDLLSRISAA SEEEAVGNGA ATPKMKQGPG TQAINRESWC AIEPCPEAAS LLASKQSSEC 1380
RSFIDVGLGT ECASKEGMLQ RVSGSESDLF HSPSDEMDSI IFPKPEEEQL LCDTTGSSSS 1440
TDDTASLDRH SSHGSDVSLP QTSKLNRSRN HQSANGFFSP GVEAPESRES ESEPAGSGEM 1500
EEEEMDSITE VPANCSFLRS SMRSLSPFRR HSWGPGKNAA SDAEMNQRSS MRALGHVVRR 1560
PPIHRRSFSL EGLTGGGVGN KPSSSLEMSS ANSSELRNPF GGEEQRNSLM SLSEEHLEPD 1620
QRQHHRMFDQ QTCYRSKQQG FNYCTSAISS PLTKSISLMT ISHPGLDSSR PFHSTSANLT 1680
ESITEENCNF LPPSPSKKNF EEKSGTKVSR TFSYIRNKMS SSKKSKEKEK EKDKIKEKEK 1740
DSKEKEKDKK TLNGHTFSPI PIVGPISCSQ CMKPFTNKDA YTCAGCGAFV HKGCRENLAS 1800
CAKVKMKQPK GSLQAHDTSS LPTVIMRNKS SQPKERPRSA VLLADEATAA PMFTNRRSQQ 1860
SVSLSKSVSI QNITGVGNDE NMSNTWKFLS HSTDSLNKIC KVNESTESLT DEGVGTDMNE 1920
GQLMGDFESD SKQLEAESWS RTVDSKFLKQ QKKDVVKRQE VIYELMQTEL HHIRTLKIMS 1980
DVYSRGMMTD LLFEQQMVEK LFPCLDELIS IHSQFFQRIL ERKKESLVDK SEKNFLIKRI 2040
GDVLVSQFSG ESAERLKKTY GKFCGQHNQS VNYFKDLYTK DKRFQAFVKK KMSSSVVRRL 2100
GIPECILLVT QRITKYPVLF QRILQCTKDN EVEQEDLTQS LSLVKDVIGA VDSKVASYEK 2160
KVRLGEIYTK TDSKSIMRMK SGQMFAKEDL RRKKLVRDGS VFLKSTTGRL KEVQAVLLTD 2220
ILVFLQEKDQ KYVFASLDHK STVISLKKLI VREVAHEEKG LFLISMGVKD PEMVEVHASS 2280
REERNSWIQI IQDTINSLNR DEDEGIPSEN EEEKKLLDTK ARELKEQLQQ KDQQILLLLE 2340
EKEMIFRDMT ECSTPLPEDC SPTHSPRVLF RSNTEEALKG GPLMKSAINE VEILQSLVSG 2400
SLGGTLGQSI SSPVEQEVMA APISLPRRAE TFGGFDCHQM NASKGGEKEE GDDGQDLRRT 2460
ESDSGLKKGG NGNLVFMLKR NSEQVVQSIV HLHELLSMLQ GVVLQQDSYI EDQKLVLTEK 2520
VLTRSASRPS SLIEQEKQRS LEKQRQDLAN LQKQQAQHLE EKRRREREWE AREQELRDRE 2580
AKLAEREETV RRRQQDLERD REELQQKKGT YQCDLERLRA AQKQLEREQE QLRRDTERLS 2640
QRQMDQNLCQ VSNKHGRLMR IPSFLPNSDE FSSPSAPSVT KSGSLDSELS VSPKRNSISR 2700
TQKDKGPFHI LGSASQTKVP EGQSQAPSST STSTRLFGLS KPKEKKEKKK KSKGSRTQPG 2760
DGPASEVPAE GEEIFC 2777
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR028852--AKAP13
IPR020683--Ankyrin_rpt-contain_dom
IPR000219--DH-domain
IPR002219--PE/DAG-bd
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR018459--RII_binding_1

PROSITE

PS50010--DH_2
PS50003--PH_DOMAIN
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF16652--PH_13
PF00621--RhoGEF
PF10522--RII_binding_1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016020--C:membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0051168--P:nuclear export
GO:0010611--P:regulation of cardiac muscle hypertrophy
GO:1900169--P:regulation of glucocorticoid mediated signaling pathway
GO:0045859--P:regulation of protein kinase activity
GO:0035023--P:regulation of Rho protein signal transduction