dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050805
Uniprot Accession E9Q238; E9Q238_MOUSE;
Genbank Protein ID NP_852069.4; XP_006526648.1; XP_011245415.1;
Genbank Nucleotide ID NM_181404.5; XM_006526585.2; XM_011247113.1;
Protein Name Protein Kank1
Protein Synonyms/Alias
Gene Name Kank1
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 20
PositionPeptidesSourceReferences ( PMIDs )
70IQKRRKPSVPCPEVRPhosphoSitePlus;curated22135298; 22817900; 21183079
128PPAPLETSPTFAVSEPhosphoSitePlus22135298
242MGSSVRHSPLSSGISPhosphoSitePlus;curated22135298; 22817900; 21183079
246VRHSPLSSGISTPVTPhosphoSitePlus;curated22135298; 22817900; 21183079
253SGISTPVTNVSPMHLPhosphoSitePlus;curated22135298; 21183079
323ACGVRKRSYSAGNASPHOSIDA;PhosphoSitePlus;SysPTM 2.0;curated21081558; 22135298; 18846507; 19366988; 25338131
324CGVRKRSYSAGNASQPhosphoSitePlus;curated22135298; 21183079
325GVRKRSYSAGNASQLPhosphoSitePlus;SysPTM 2.0;curated22135298; 18846507; 19366988; 22817900; 21183079; 25338131
330SYSAGNASQLELLARPhosphoSitePlus22135298
410CKSVAVGSDENMNDVPhosphoSitePlus;curated22135298; 22817900; 21183079
674VMAVPHTTDQHTSTNcurated25521595
678PHTTDQHTSTNLERVcurated25521595
701ATLVESCTNTLLSTMcurated25521595
887NSVMKSASTEELRNSPhosphoSitePlus;curated22135298; 21183079; 20469934; 25338131
1339LNFSKAQSPSTPRLGPhosphoSitePlus;curated22135298; 23684622
1341FSKAQSPSTPRLGRKPhosphoSitePlus;curated22135298; 23684622
1349TPRLGRKTSPGPTHRcurated23684622
1350PRLGRKTSPGPTHRGPhosphoSitePlus;curated22135298; 23684622; 25338131
1354RKTSPGPTHRGSFD-curated23684622
1358PGPTHRGSFD-----PhosphoSitePlus;curated22135298; 23684622; 21183079; 25338131
Sequence
(Fasta)		MAYTTKVNGC AAEKADGVLN GDHNKEKKDP YFVETPYGFQ LDLDFVKYVD DIQKGNTIKK 60
LNIQKRRKPS VPCPEVRAIP GHQGVWTSTE SLSSSNSDDS KQCPSFLLAR SHVTSTPIPR 120
PPAPLETSPT FAVSENRQLL PPPSPQLPRH NLHVTKTLME TRRRLEQERV TMQMAPGDFR 180
RPRLASFGGM GSTSSLPSFV GSANHSSAIH QLQNGYQGNG DYNSYVPAAP TTSSMGSSVR 240
HSPLSSGIST PVTNVSPMHL QHIREQMAIA LKRLKELEEQ VRTIPVLQVK ISVLQEEKRQ 300
LASQLKSQRA SSQNEACGVR KRSYSAGNAS QLELLARARR GGGELYIDYE EEEMESVEQS 360
TQRIQEFRQL TADMQALERK IQDSSCEVAS ELRENGQCPS RECKSVAVGS DENMNDVVVY 420
HRDLRPCKDT AVGTVTETRN VGISVTEAML GVITEADKEI ELQQQTIEAL KEKIYRLEVQ 480
LKETTHDREM TKLKQELQAA GSRKKVDKAT MAQPLVFSKL VEALVPTRDQ MVGSHVDTRE 540
SCVGTSVQTS SVGTSCHPDC KNQVVGSELP MNWWVVKERV AMHDQCVGRS VETCDRSVGV 600
EVSVCETGSN TEASGSDLTL LKTNLNLKDV RSIGCGDCSV DVIVCFPKEC TSRSMNTEAV 660
GQEEAAVMAV PHTTDQHTST NLERVDQCTN TEAATLVESC TNTLLSTMDK QTSTQTVEMR 720
TVAIGEGRVR DINPSTKTRS VGVGTVLSGN SEFDRPCAVK TKESGVGQIN IQDNYLVGLK 780
MRTIACGPPQ LTVGLMGSRR SVGVGNEPVG ELPEESPQPR VASGMVTGLD HYIERVQRLL 840
AEQQTLLAEN YSELAEAFGE PHSQIGSLNS QLISTLSSIN SVMKSASTEE LRNSDFQKAS 900
LGKTTGNHLE YTCKCGGLRS GGLLNVQPSQ PEVEAETAEG KHSRGHEQFP MQGSTLPPVN 960
LTDDQIATGL YVCPNNENTL KSIMKKSDGN KDSNGAKKNL QFIGINGGYE TTSSDESSSD 1020
GSSSSESDDE CDTIGYPPEE EEEEEEKDHD TRGMAEGHHA VNIEGFKSAR VEDEVQVPEC 1080
EPEKEEIRER YELSEKMLSA CNLLKYNIKD PKALASKDMR ICLNTLQHDW FRVSSQKSAV 1140
PAMVGDYIAA FEAVSPDVLR YIINMADGNG NTALHYSVSH SNFQIVKLLL DADVCNVDHQ 1200
NKAGYTPIML AALAAVEAEK DMQVVEELFS CGDVNAKASQ AGQTALMLAV SHGRIDMVKG 1260
LLACGADVNI QDDEGSTALM CASEHGHVEI VKLLLAQPGC NGHLEDNDGS TALSIALEAG 1320
HKDIAVLLYA HLNFSKAQSP STPRLGRKTS PGPTHRGSFD 1361
Keyword

KW-0040--ANK repeat
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR021939--KN_motif
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
Pfam

PF12796--Ank_2
PF12075--KN_motif
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0032587--C:ruffle membrane
GO:0008013--F:beta-catenin binding
GO:0030837--P:negative regulation of actin filament polymerization
GO:0030336--P:negative regulation of cell migration
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:2000393--P:negative regulation of lamellipodium morphogenesis
GO:0010977--P:negative regulation of neuron projection development
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:1900028--P:negative regulation of ruffle assembly
GO:1900025--P:negative regulation of substrate adhesion-dependent cell spreading
GO:0035413--P:positive regulation of catenin import into nucleus
GO:0030177--P:positive regulation of Wnt signaling pathway
GO:0090303--P:positive regulation of wound healing
GO:2000114--P:regulation of establishment of cell polarity