dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050790
Uniprot Accession A6H650; A6H650_MOUSE; E9Q1N6;
Genbank Protein ID NP_081802.1; XP_006506662.1;
Genbank Nucleotide ID NM_027526.1; XM_006506599.1;
Protein Name MCG133012
Protein Synonyms/Alias
Gene Name Rasgef1a
Gene Synonyms/Alias mCG_133012;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
165QCDEENGTVKKAIAQPhosphoSitePlus22135298
196ELREKLRSPVVDKGPPHOSIDA;PhosphoSitePlus21081558; 22135298
Sequence
(Fasta)		MPQTSVVFSS ILGPNCNRQV QPGMGERGGG ASSGSKDLIF QDGRLTSGSL EALMEHLVPT 60
VDYYPDRTYI FTFLLSSRVF MPPHDLLARV GQICLEQRQQ LEAGPEKAKL KSFSTKIVQL 120
LKEWTEAFPY DFQDEKVMAE LKAIAHRVTQ CDEENGTVKK AIAQMIQSLL LSLAARSQLQ 180
ELREKLRSPV VDKGPVLKAK PPAAQKDILG VCSDPLVLAQ QLTHIELERV NSIRPEDLMQ 240
IISHMDSLDN HRCRGDMTKT FSLEAYDNWF NCLSMLVATE VCRVVKKKHR TRMLEFFIDV 300
ARECFNIGNF NSMMAIISGM NLSPVARLKK TWSKVKTAKF DVLEHHMDPS SNFCNYRTAL 360
QGATQRSQTA NSSREKIVIP VFNLFVKDIY FLHKIHTNHL PNGHINFKKF WEISRQIHEF 420
MTWTQVECPF EKDKKIQSYV LTAPIYSEEA LFIASFESEG PENHMEKDSW KALRTTLLNR 480
A 482
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR000651--Ras-like_Gua-exchang_fac_N
IPR023578--Ras_GEF_dom
IPR001895--RASGEF_cat_dom
PROSITE

PS50009--RASGEF_CAT
PS50212--RASGEF_NTER
Pfam

PF00617--RasGEF
PF00618--RasGEF_N
Gene Ontology

GO:0005622--C:intracellular
GO:0005088--F:Ras guanyl-nucleotide exchange factor activity
GO:0016477--P:cell migration
GO:0043547--P:positive regulation of GTPase activity
GO:0046579--P:positive regulation of Ras protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction