dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050780
Uniprot Accession E9Q0S6; E9Q0S6_MOUSE;
Genbank Protein ID NP_082160.3;
Genbank Nucleotide ID NM_027884.3;
Protein Name Protein Tns1
Protein Synonyms/Alias
Gene Name Tns1
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 161 (View all)
PositionPeptidesSourceReferences ( PMIDs )
140EGDCRVGSSPKNLEEcurated21183079
141GDCRVGSSPKNLEEGcurated20469934
150KNLEEGGSMRVSPSIPhosphoSitePlus;curated22135298; 21183079; 25338131
154EGGSMRVSPSIQPQPPhosphoSitePlus;SysPTM 2.0;curated22135298; 17242355; 19366988; 21183079; 25338131
156GSMRVSPSIQPQPQSPhosphoSitePlus;SysPTM 2.0;curated22135298; 17242355; 19366988; 21183079; 25338131
163SIQPQPQSQPTSLSRPhosphoSitePlus;curated22135298; 21183079; 25338131
166PQPQSQPTSLSRNTSPhosphoSitePlus;curated22135298; 21183079
167QPQSQPTSLSRNTSVPhosphoSitePlus;curated22135298; 21183079; 25338131
169QSQPTSLSRNTSVSRPhosphoSitePlus;curated22135298; 21183079; 25338131
172PTSLSRNTSVSRAMEcurated25338131
173TSLSRNTSVSRAMEDPhosphoSitePlus;curated22135298; 21183079; 25338131
175LSRNTSVSRAMEDSCcurated25338131
239SEQRPDITKLHAKVLPhosphoSitePlus;curated22135298; 21183079
347FSGLLSGSIKMNNKPcurated21183079
501VSVDYNTSDPLIRWDPhosphoSitePlus;curated22135298; 21183079
509DPLIRWDSYDNFSGHPHOSIDA;PhosphoSitePlus;SysPTM 2.0;curated21081558; 22135298; 17242355; 19366988; 23684622; 21183079;
510PLIRWDSYDNFSGHRPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 21183079
514WDSYDNFSGHREDGMPhosphoSitePlus;curated22135298; 21183079
535TQGPLDGSLYAKVKKPhosphoSitePlus;SysPTM 2.0;curated22135298; 17242355; 19366988; 21183079
537GPLDGSLYAKVKKKDPhosphoSitePlus;SysPTM 2.0;curated22135298; 18515860; 19366988; 17242355; 25195567; 21183079;
Sequence
(Fasta)		MGCTVSLVCC EALEPLPSCG PQPPGTPPGP ARPERCEPGG AAPDPRRRLL LQPEDLEAPK 60
THHFKVKAFK KVKPCGICRQ AITREGCVCK VCSFSCHRKC QAKVAAPCVP PSSHELVPIT 120
TETVPKNVVD VGEGDCRVGS SPKNLEEGGS MRVSPSIQPQ PQSQPTSLSR NTSVSRAMED 180
SCELDLVYVT ERIIAVSFPS TANEENFRSN LREVAQMLKS KHGGNYLLFN LSEQRPDITK 240
LHAKVLEFGW PDLHTPALEK ICSVCKAMDT WLNADPHNVV VLHNKGNRGR IGVVIAAYLH 300
YSNISASADQ ALDRFAMKRF YEDKIVPIGQ PSQRRYVHYF SGLLSGSIKM NNKPLFLHHV 360
IMHGIPNFES KGGCRPFLRI YQAMQPVYTS GIYNIPGDSQ ASICITIEPG LLLKGDILLK 420
CYHKKFRSPA RDVIFRVQFH TCAIHDLGVV FGKEDLDEAF KDDRFPDYGK VEFVFSYGPE 480
KIQGMEHLEN GPSVSVDYNT SDPLIRWDSY DNFSGHREDG MEEVVGHTQG PLDGSLYAKV 540
KKKDSLNGSS GPVTTARPAL SATPNHVEHT LSVSSDSGNS TASTKTDKTD EPVSGATTAP 600
AALSPQEKKE LDRLLSGFGV DREKQGAMYR AQQLRSHPGG GPTVPSPGRH IVPAQVHVNG 660
GALASERETD ILDDELPIQD GQSGGSMGTL SSLDGVTNTS ESGYPETLSP LTNGLDKPYS 720
TEPVLNGGGY PYEAANRVIP VHSSHSAPIR PSYSAQEGLA GYQREGPHPA WSQQVTSAHC 780
GCDPSGLFRS QSFPDVEPQL PQAPTRGGSS REAVQRGLNS WQQQQPHPPP RQQERSPLQS 840
LARSKPSPQL SAETPVAALP EFPRAASQQE IEQSIETLNM LMLDLEPASA AAPLHKSQSV 900
PGAWPGASPL SSQPLLGSSR QSHPLTQSRS GYIPSGHSLG TPELVSSGRP YSPYDYQLHP 960
AGSNQSFHPK SPASSTFLPS PHSSAGPQEP PASLPGLIAQ PQLPPKETTS DPSRTPEEEP 1020
LNLEGLVAHR VAGVQARERQ PAEPPGPLRR RAASDGQYEN QSPEATSPRS PGVRSPVQCV 1080
SPELALTIAL NPGGRPKEPH LHSYKEAFEE MEGTSPSSPP HSVARSPPGL AKTPLSALGL 1140
KPHNPADILL HPTGVARRLI QPEEDEGEEV TKPPEEPRSY VESVARTAVA GPRAQDVEPK 1200
SFSAPAAHAY GHETPLRNGT PGGSFVSPSP LSTSSPILSA DSTSVGSFPS VVSSDQGPRT 1260
PFQPMLDSSI RSGSLGQPSP AALSYQSSSP VPVGGSSYNS PDYSLQPFSS SPESQGQPQY 1320
SAASVHMVPG SPQARHRTVG TNTPPSPGFG RRAVNPTMAA PGSPSLSHRQ VMGPSGPGFH 1380
GNVVSGHPAS AATTPGSPSL GRHPVGSHQV PGLHSSVVTT PGSPSLGRHP GAHQGNLASS 1440
LHSNAVISPG SPSLGRHLGG SGSVVPGSPS LDRHAAYGGY STPEDRRPTL SRQSSASGYQ 1500
APSTPSFPVS PAYYPGLSSP ATSPSPDSAA FRQGSPTPAL PEKRRMSVGD RAGSLPNYAT 1560
INGKVSSSPV ANGMASGSST VSFSHTLPDF SKYSMPDNSP ETRAKVKFVQ DTSKYWYKPE 1620
ISREQAIALL KDQEPGAFII RDSHSFRGAY GLAMKVSSPP PTITQQGKKG DMTHELVRHF 1680
LIETGPRGVK LKGCPNEPNF GSLSALVYQH SVIPLALPCK LVIPSRDPTD ESKDSSGPAN 1740
STTDLLKQGA ACNVLFVNSV DMESLTGPQA ISKATSETLA ADPTPAATIV HFKVSAQGIT 1800
LTDNQRKLFF RRHYPLNTVT FCDLDPQERK WMKTEGGAPA KLFGFVARKQ GSTTDNACHL 1860
FAELDPNQPA SAIVNFVSKV MLSAGQKR 1889
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0862--Zinc
Interpro

IPR000008--C2_dom
IPR002219--PE/DAG-bd
IPR011993--PH/PTB_dom
IPR029021--Prot-tyrosine_phosphatase-like
IPR013625--PTB
IPR006020--PTB/PI_dom
IPR000980--SH2
IPR014020--Tensin_C2-dom
IPR029023--Tensin_lipid_phosphatase_dom
PROSITE

PS51182--C2_TENSIN
PS51181--PPASE_TENSIN
PS50001--SH2
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2
Pfam

PF08416--PTB
PF10409--PTEN_C2
PF00017--SH2
Gene Ontology

GO:0030055--C:cell-substrate junction
GO:0005925--C:focal adhesion
GO:0005622--C:intracellular
GO:0003779--F:actin binding
GO:0046872--F:metal ion binding
GO:0044822--F:poly(A) RNA binding
GO:0007044--P:cell-substrate junction assembly
GO:0010761--P:fibroblast migration
GO:0035556--P:intracellular signal transduction