dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050772
Uniprot Accession E9Q0B6; E9Q0B6_MOUSE;
Genbank Protein ID NP_001158141.1;
Genbank Nucleotide ID NM_001164669.1;
Protein Name Protein Dnah6
Protein Synonyms/Alias
Gene Name Dnah6
Gene Synonyms/Alias Dnahc6;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
14EDEIDLKSIEHQAEEPhosphoSitePlus22135298
983VDALLVDTEIPLTLEPhosphoSitePlus22135298
1577NPGYAGRTELPDNLKPhosphoSitePlus22135298
3058LPRDLISTENGILVTPhosphoSitePlus22135298
3065TENGILVTQGRRWPLPhosphoSitePlus22135298
3141LLKQTFMSGGRLLIHPhosphoSitePlus22135298
3152LLIHLGDSDIDYDKSPhosphoSitePlus22135298
3156LGDSDIDYDKSFRFYPhosphoSitePlus22135298
Sequence
(Fasta)
MAFQGTEDEI DLKSIEHQAE ENPILARLNK IKAKGILNYV SLKENEPEPP TLVFRHTTKA 60
QERTRKRQQP VKLEPLPVLK VYQDHKQPEY IYEQNRQKLM SSGILKPSPS TADRASIISL 120
EAQEAVKRKQ VHRPSADVFS PSPTKLPRTS IGRRGLFGMR SSTYPTYTFH DREEVIKANI 180
RDPLQIIKIV HENEHLGFLY MISAVPKSSI EYDTYNLKVV SYENINKNDY YTISKDAVTH 240
VYNDDIEYIE IERWEQEYLY HRELTKIPIF ALFRKWKAFS VWRKNVRSKK ITGCRKALRK 300
NLFIVNPYLR PALLKINEMC YLLSFMGLCY IEKFHTYTLQ EFKAAQIVRL QEVTERLEVF 360
RCAAKDVVRK SCRFALRAAG FIPDDCEVET YEDYFKANIA SLVDGPFDLP TYGESEKMTY 420
TEQASKRHHC MRLTCFIRLN DYLIQNTLHV LTVNTASSLL NFFSDKLKRT PSADVIQKWI 480
TEEKPEVTEK KGAPLMEKQE EDESLVPMFL TELILTVQSL LFEPSLEDFL DGISGAINHF 540
ENTVLSVPNL VPDSYFDAFT SPFINKKVEE KTCGPGPNLS AVFEDDRNFL TIIMQIKETI 600
HAAFDSARLY AATFEKFQLF FKENESLDLE ALKQEEPDVQ FFSSQLEKYH KQHKDSVALR 660
PTRNVGLLLI DTKQLKEKLI PSPLRCLEVL NSMLPCLSKK KVDAIISEAQ DAEYKLEFMP 720
TTTIEYVNSL VFLDEIQERI ETLEEEANVV VQMYKLIEQY QVPTPPEDFA VFATMKPSIT 780
AVRNAIDKSV GDRETSIKQF CLHLGRDLED LNNEVNEVKL LAQDPQILDI SADQEKIKTM 840
LSDLQSVLDD LQKRAFQYKS YQKNFKVEVS KFDALEEVSA ELRLKQLLWD SLSEWDNLQQ 900
EWLKSKFDCL DPEVLNSQVT KYAKFVTQLE KGLPPNSVVP QLKQKVEKMK EKLPVIIDLR 960
NPTLKARHWA AIEQTVDALL VDTEIPLTLE RLSELHVFNF AQEIQDISGQ ASGEAALEII 1020
LKKVEDSWKT TEFVILPHRD SKDVFILGGT DDIQVLLDDS TINIATIASS RYVGPLKSRV 1080
DDWQKQLSLF NQTLEEWLNC QRNWLYLESI FNAPDIQRQL PAEAKMFLQV DKSWKEIMRK 1140
VNRLPNALRA ATQPGLLETF QNNNALLDQI QKCLEAYLES KRVIFPRFYF LSNDELLEIL 1200
AQTRNPQAVQ PHLRKCFDSI SKLEFALMPP TEGKIPGMDT EPEKVFTNDI LAMLSPEGER 1260
VGLGKGLKAR GNVEEWLGKV EEAMFTSLRR LCKAAIADYQ GKPRTEWVIA GHPSQVILTI 1320
SQIMWCRDLT ESLECEGDNV DALEDFEQVN FERLNALAAI VRGNLPKLHR NIITALITID 1380
VHARDIVSEL VQAKVDSADS FDWQRQLRYY WDMDLDNCVA RMALSQYTYA YEYLGACPRL 1440
VITPLTDRCY LCLMGALQLD LGGAPAGPAG TGKTETTKDL AKALAIQCVV FNCSDGLDYK 1500
MMGRFFSGLA QSGAWCCFDE FNRIDIEVLS VIAQQLITIR NAKAAKLSRF MFEGREIKLV 1560
MTCAAFITMN PGYAGRTELP DNLKALFRPM AMMVPNYALI AEVILYSEGF ESSKILARKM 1620
TQMYKLCSEQ LSQQDHYDFG MRAVKSVLVM AGSLKRENPD LSEDVVLIRA LRDSNLPKFL 1680
TDDALLFSGI ISDLFPGVQI PEHDYGILQS TIVEVMINQN LQPELCMVKK VIQLYETMLV 1740
RHGVMLVGPT GGGKTTVYQV LAETLGNLEK LNTDNPFYQP VKTYVLNPKS ITMGELYGEV 1800
NNVTLEWKDG LMALSVRAAV NDTSEDHKWI ISDGPVDALW IENMNTVLDD NKMLCLANSE 1860
RIKLTPQIHM LFEVQDLRVA SPATVSRCGM VFVDPEELKW MPYVKTWMRT MSKKLNDEVQ 1920
EYLLNLFNRY VDDGLHFVNK KCTQAIPQVD ISKVTTLCCL LESLLLSKDG NILSMEQMKL 1980
NTVLCQTFVF CYLWSLGGNL TENYWDSFDT FIRTQFDDNP DARLPSSGDL WSIHIDFDTK 2040
RLDPWERIIP TFKYSRDVPF FEMLVPTTDT VRYGYLMEKL LAVRHSVLFT GTTGVGKSVI 2100
AKGLLNRIQE SAGYVPVYLN FSAQTSSSRT QEIIESKLER KRKNILGAPG NKQVVIFVDD 2160
LNMPRLDRYG SQPPIELLRQ YQDFGGFYDR NKLFWKEIQD VTIVSACAPP GGGRNPVTPR 2220
FIRHFSMLCL PMPSEHSLKQ IFQAILNGFL ADFPEAVKQT SSNIVEAAVE IYNRMSVDLL 2280
PTPAKSHYVF NLRDLSKCVQ GILQCDPGTI REELQIFRLF CHECQRVFHD RLINNEDKHY 2340
FHLILTEMAN KHFGIAIDLE YFLSKPIIFG DFIKFGAEKS DRIYDDLPDM EKIENVLQDY 2400
LDDYNLTNPK EVKLVFFQDA IEHVSRIARM IRQERGNALL VGVGGTGKQS LTRLAAHICG 2460
YKCMQIELSR GYNYDNFHED LRKLYKMAGV EDKDMVFLFT DTQIVVEEFL EDINNILNSG 2520
EVPNLFEKDE LEHVLAATRP KAKEVGISEG NRDEVFQYFI SRVRQKLHIV LCMSPVGEAF 2580
RSRCRMFPSL VNCCTIDWFV QWPREALLSV SKSFFSSVDT GNDDLREKLS LMCVNVHLSV 2640
SHMAERYYNE LRRRYYTTPT SYLELINLYL TMLTEKRKQL VSARDRVKNG LTKLLETNVL 2700
VDKMKLDLSA LEPVLLQKSQ DVEALMEKLV VDQESADQVR NVVQEDEAIA KVKAEETQAI 2760
ADDAQRDLEE ALPALEAANK ALDSLDKADI SEIRVFTKPP DLVMTVMEAI SILLNAKPDW 2820
PTAKQLLGDS NFLRRLLEYD KENIKPQILL KLQKYINNPD FVPEKVEKVS KACKSMCMWV 2880
RAMDLYSRVV KEVEPKRQKL RAAQAELDAT MATLKEKQAL LKQVEDQIKT LQDKYEKGVN 2940
EKESLAKNMA LTKARLIRAG KLTAALGDEQ VRWEESIEKF QEELANIVGN VFIAAACVAY 3000
YGAFTAQYRQ LLIEWWIESC LALEIPIDPS FSLINILGDP YEIRQWNTDG LPRDLISTEN 3060
GILVTQGRRW PLMIDPQDQA NRWIRNKESK SGLKVIKLTD TNFLRILENS IRLGLPVLLE 3120
ELREVLDPAL EPILLKQTFM SGGRLLIHLG DSDIDYDKSF RFYMTSKMPN PHYLPEVCIK 3180
VTIINFTVTK SGLEDQLLSD VVRLEKPELE EQRIQLIVRI NSDKNQLKSI EDKILKLLFT 3240
SEGNILDNEE LIDTLQDSKI TSGAIKTRLK EAESTELMIN IARERYRPVA TQGSVMYFVI 3300
ASLSEIDPMY QYSLKYFKQL FNTTIETSEK SDNLHERLKI LLQQTLLTAY TNVSRGLFEQ 3360
HKLIYSFMLC VDIMREHEQL TEAEWNFFLR GSAGMEKERP PKPEAPWLPI QMWFSCCDLE 3420
ESFPIFEGLT KHILLRPISI KLGSFETYIN PPVWEGYPKQ RHEEEKDHVW GLDFSSFHKL 3480
ILVKCCKEEK VVFALTDFVI ENLGKQFIET PPVDLATLYQ DMSNSTPLVF ILSTGSDPMG 3540
AFQRFARESG YAERVQSISL GQGQGPIAEK MIKDAMKTGN WVFLQNCHLA VSWMLAMEEL 3600
IKTFTDPNQT IKDTFRLFLS SMPCSTFPVT VLQNSVKVTN EPPKGLRANI RRAFTEMTPS 3660
FFEENILGMK WRKLIFGICF FHAIIQERKK FGPLGWNICY EFNDSDRECA LLNLNLYCHE 3720
GKIPWDALIY ITGEITYGGR VTDTWDQRCL RTVLKRFFSP ETLDDDYTYS DSGIYFAPLA 3780
DSLQDFKEYI EDLPLIDDPE IFGMHENANL VFQYKETNTL ITTILEVQPR SSSGGQGKSN 3840
DEIVQELVAS IQTRVPESLQ MEGASESLFV KDPQGRLNSL TTVLGQEVDR FNNLLKLIHI 3900
SLETLNKAIA GLVVMSEEME KVYQSFLNNQ VPSLWSNTAY PSLKPLGSWV KDLILRTEFV 3960
DLWLKRGQPK SFWISGFFFP QGFLTGTLQN HARKYNLPID ELSFKYNMIP VYRDQAAVIE 4020
SAKDIQFGTE LPMDKELPSP EDGVLVHGMF MDASRWDDKD MVIEDALPGQ MNPMLPVVHF 4080
EPKQNYEPVH TLYHSPLYKT GARAGTLSTT GHSTNFVVTV LLPSKRISDY WISKGSALLC 4140
QLSE 4145
Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR003593--AAA+_ATPase
IPR011704--ATPase_dyneun-rel_AAA
IPR026983--DHC_fam
IPR026980--DNAH6
IPR024743--Dynein_HC_stalk
IPR024317--Dynein_heavy_chain_D4_dom
IPR004273--Dynein_heavy_dom
IPR013602--Dynein_heavy_dom-2
IPR027417--P-loop_NTPase

PROSITE
Pfam

PF07728--AAA_5
PF12780--AAA_8
PF08393--DHC_N2
PF03028--Dynein_heavy
PF12777--MT

Gene Ontology

GO:0036156--C:inner dynein arm
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0003341--P:cilium movement
GO:0001539--P:cilium or flagellum-dependent cell motility