dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050769
Uniprot Accession E9Q0A3; E9Q0A3_MOUSE;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Protein Arhgef11
Protein Synonyms/Alias
Gene Name Arhgef11
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
557STFHIPLSPVEVKPGPhosphoSitePlus;curated22135298; 21743459
Sequence
(Fasta)
MSIRLPHSID RLSSLSSLGD STPERTSPSH HRQPSDTSET TGLVQRCVII QKDQHGFGFT 60
VSGDRIVLVQ SVRPGGAAMR AGVKEGDRII KVNGTMVTNS SHLEVVKLIK SGAYVALTLL 120
GSSPSSIGVS GLQQNPSLSG GPRVNPMIPP PPPPPPLPPP QHITGPKPLQ DPEVQKHATQ 180
ILRNMLRQEE KELQDVLPLC GETSQRTCEG RLSVDSQEAD SGLDSGTERF PSISESLVNR 240
NSVLSDPGLD SPQTSPVILA RVGQHHRRQG SDAAVHPLNH QGIDQSPKPL IIGPEEDYDP 300
GYFNNESDII FQDLEKLKSH PAYLVVFLRY IFSQADPGPL LFYLCSEVYQ QTNPKDSRNL 360
GKDIWNIFLE KNAPLRVKIP EMLQAEIDLR LRNSEDPRSA LYEAQEAVMP EIQEQINDYR 420
SKRTLGLGSL YGENDLLDLD GDPLRERQMA EKQLAALGDI LSKYEEDRSA PMDFAVNTYM 480
SHTGIRLRES RPSSTAEKTQ SAPDKDKWLP FFPKTKKQSS NSKKEKDALE DKKRNPILRY 540
IGKPKSSSQS TFHIPLSPVE VKPGNVRNII QHFENSHQYD VPEPGTQRLS TGSFPEDLLE 600
SDSSRSEIRL GRSESLKGRE EMKRSRKAEN VPRSRSDVDM DAAAEATRLH QSASSSASSL 660
STRSLENPTP PFTPKMGRRS IESPNLGFCT DVILPHLLED DLGQLSDLEP EPEVQNWQHT 720
VGKDVVANLT QREIDRQEVI NELFVTEASH LRTLRVLDLI FYQRMKKENL MPREELSRLF 780
PNLPELIEIH NSWCEAMKKL REEGPIIRDI SDLMLARFDG PAREELQQVA AQFCSYQSVA 840
LELIRTKQRK ESRFQLFMQE AESHPQCRRL QLRDLIISEM QRLTKYPLLL ENIIKHTAGG 900
TSEYEKLCRA RDQCREILKF VNEAVKQTEN RHRLEGYQKR LDATALERAS NPLAAEFKSL 960
DLTTRKMIHE GPLTWRISKD KTLDLQVLLL EDLVVLLQRQ EEKLLLKCHS KTAVGSSDSK 1020
QTFSPVLKLN AVLIRSVATD KRAFFIICTS ELGPPQIYEL VALTSSDKNI WMELLEEAVQ 1080
NATKHPGDAP VLNHPSPPGS QEPAYQGSTS SRVEVNDSEV YPTEREPKKP SEGPGPEQRG 1140
QDKQLLAQEG PEQEEDAEEL RALPCPPPSL DGENRGIRTR DPVLLALTGP LLMEGLADAA 1200
LEDVENLRHL ILWSLLPGHT VKTQAAGEPE DDLTPTPSVV SITSHPWDPG SPGQAPAISD 1260
NTQFPRPEGS QPEGEDVALC SLAHLPPRTR NSGIWDSPEL DRNPAEEASS SEPAGSYKVV 1320
RKVSLLPGGG VGAAKVAGSN VTPALPESGQ SESELSEVEG GAQATGNCFY VSMPAEPLDS 1380
STEPPGTPPS LSQCHSLPAW PTEPPQHRGV TGGQRSSLVL RDMGVIFHTI EQLTVKLHRL 1440
KDMELAHREL LNSLGGESSG GTTPVGSFHT EAARW 1476
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR001478--PDZ
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR016137--RGS
IPR015212--RGS-like_dom

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50106--PDZ
PS50003--PH_DOMAIN
PS50132--RGS

Pfam

PF00595--PDZ
PF16652--PH_13
PF09128--RGS-like
PF00621--RhoGEF

Gene Ontology

GO:0005737--C:cytoplasm
GO:0001664--F:G-protein coupled receptor binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007266--P:Rho protein signal transduction