dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050761
Uniprot Accession E9PZQ1; E9PZQ1_MOUSE;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Protein Ddx60
Protein Synonyms/Alias
Gene Name Ddx60
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
13TGFLKIMSHLILETMPhosphoSitePlus22135298
212MIMIVYKSLIQQLEKPhosphoSitePlus22135298
220LIQQLEKYRDMALAHPhosphoSitePlus22135298
Sequence
(Fasta)
MEKKYTGFLK IMSHLILETM SKADYSSLFN DFVESEFFLI DGDSLLITCA CERSLKPGQS 60
LHFFYLVERY LLDVISKGGQ FAIVFFKDAE YAYFNVPELL TLRTALILHL QKNTTVEVWT 120
KFSNCLSEEW NICLGQSCPY FLILADEGLN DLQTHLFNFV VIQAWAAKVN IVLFSGQTSD 180
ILRLYAYFMQ SSHGMQMFFK ENKRMIMIVY KSLIQQLEKY RDMALAHLFG DLKFNDMEEK 240
VCETVSLLKQ LWPEGSDIRC VFCVTSCSLF LEMYHCYLES REKGASEEMS KVKQKTDNCL 300
TLKDMEDFCK LHCLSVALLL HVPLSQRARS RFITANWIQD LKTVLKMKKW CEYFILSNLD 360
MFESWSLNLL HLSDLSDEPL LRNIAFYYEN ENKEGLDLNV GDAIMNEYVH LWDTVSKLVR 420
KFDVGKPIPL RTTKVHFLEK TPSPIKESSQ EMMPNLGFIP MSCNLVDEFT GDILKDLPFL 480
MSDDPIVTSL VKHKEFDELV HWHSHRPLSD DYDRTKCIGD ANRRDPNHLK RLQKYHSFQR 540
FYGESLESVT SKTITTQGPK PKKDCIKSKS TKAHETKAEI IKRENKKRLI AEEEQKEEQK 600
WNALSFSIEE EMRKNVDSGM KKLEEFLKSC KSRSVKAQVE RVGLQACLKA WKEHCQAEGE 660
TTKDLSIAVN MMKRIHSLLD KHSELLQEAD QKLIARCLKY LGFCELAVSL YPTQDASDGI 720
KMKKKNKYSV GIGPARFQLQ YMGHYLIREE RKDPDPRVQD FIPDTWQREL LDVVDNYESA 780
VIVAPTSSGK TYASYYCMEK VLKESDEGVV VYVAPTKALV NQVAATVEYR YAKNMPAGES 840
LCGVFTRDYR HDALNCQVLI TVPACFEILL LAPHRQNWVK RIRYVIFDEV HCLGGEIGAE 900
IWEHLLVMIR CPFLALSATI SNPQHLTEWL QSVKRYWKQV DSTMEERTVS KRTGTSRGSY 960
YKDQAQARQS YKVRLVLYGE RYNDLEKYLC SVRQGDVCFD HFHPCAALTI DHIEKYGFPS 1020
DLALSPRESI QLYDTMCQVW KSWPQAQSLC PENFTQFKNK IVIKKLDARK YEESLKEEFT 1080
NWVKNGNEEE ARMVLKKLSP DYHEHSGRML DFFPCLVEKL RKMEKLPALF FLFKLNIVEE 1140
CAENAFEFLE KKQEEKRPPK ADKEARTTAN KLRKVKKSLE KQKTVDEKGQ KSSRRLDESV 1200
MHETEHNYLL QTLEKNLEIP KDCTYANQKA IDDQLLQRVF HRVRFERKGE TLKRLAERGI 1260
GYHHSSMSAK EKQLVEILFR KGFIRVVTAT GTLALGINMP CKSVVFAQNS VYLDALNYRQ 1320
MSGRAGRRGQ DLLGDVYFFD IPLPKIGKLI KSKVPELRGQ FPLSISLILR LMLLASKADD 1380
LEDGKAKALS VLKHSLLSFK QPRAIDMLKL YFLYSLQFLV KEGHIDQEGN PTGFAGLVSH 1440
LHYHEPSNLV FVSFLVKGLF HKLCQPTREG PKRFSEDVME KLVLVLANLF GRRYIPAKFY 1500
EVNSKFYQSK VFLDDLPEDF SHALLEYNTQ VTEDFASFLL MVSRLADMKQ EYQLSLSKIE 1560
FTGKECEDSP LVSHLMNCKE GRVAVSPFVC LSGNFDVDLL SPGVPNHVIL HTLGINHTQA 1620
PVLWPYALDS QGRKIPLNAY ALDFYKHGSL IGLVQDNRIH PGEAYSLLKD FNLIIKSISV 1680
SLRELCENEE DNVVLAFEQL STSFQEKFEL V 1712
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0347--Helicase
KW-0378--Hydrolase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR011545--DEAD/DEAH_box_helicase_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER

Pfam

PF00270--DEAD
PF00271--Helicase_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0045111--C:intermediate filament cytoskeleton
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0004386--F:helicase activity
GO:0003723--F:RNA binding
GO:0003727--F:single-stranded RNA binding
GO:0051607--P:defense response to virus
GO:1900245--P:positive regulation of MDA-5 signaling pathway
GO:1900246--P:positive regulation of RIG-I signaling pathway
GO:0009615--P:response to virus