Tag |
Content |
dbPAF ID |
dbPAF-0050749 |
Uniprot Accession |
E9PZ36; E9PZ36_MOUSE; |
Genbank Protein ID |
NP_694819.2; |
Genbank Nucleotide ID |
NM_153179.3; |
Protein Name |
Protein Pkhd1 |
Protein Synonyms/Alias |
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Gene Name |
Pkhd1 |
Gene Synonyms/Alias |
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Organism |
Mus musculus(Mouse) |
NCBI Taxa ID |
10090 |
Functional Description (View all) |
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Phosphorylation Sites
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dbPAF PTMs: 10 Position | Peptides | Source | References ( PMIDs ) |
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1102 | ARAFTYVSSLNPVIV | PhosphoSitePlus | 22135298 | 1110 | SLNPVIVSLSRNRSS | PhosphoSitePlus | 22135298 | 1112 | NPVIVSLSRNRSSIA | PhosphoSitePlus | 22135298 | 1375 | RMGFANMSVVPQKFE | PhosphoSitePlus | 22135298 | 1877 | EVLIYNSSCNITMET | PhosphoSitePlus | 22135298 | 2251 | TWGLKVDSNVFYKIV | PhosphoSitePlus;SysPTM 2.0 | 22135298; 17203969; 19366988 | 2948 | AAEVGLLTRNIRIQP | PhosphoSitePlus | 22135298 | 3220 | APQSANWTSTDRAPS | PhosphoSitePlus | 22135298 | 3221 | PQSANWTSTDRAPSN | PhosphoSitePlus | 22135298 | 3222 | QSANWTSTDRAPSNP | PhosphoSitePlus | 22135298 |
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Sequence (Fasta) | MMLAWLVSLL SMEVLLLAKP YSSFQFEPAE GSLAGGTWIT VVFDGLDRSI LYPNNGSQLQ 60 IDLVSVAIPT LRIPCDVSPA FVDLPVVTCQ TRSLPSEADA GPYSLEMRSG EQVLGTPCPG 120 SLDSCTFKFS KDQTPVLYQV YPASGVPGEV VSVYGRVITT WLETFDPDVD YIESPLILEA 180 REDKWLTPCS LINRQTGSCF PIQEEHGLGN VQCRVEGDYI GSQNVSFSVF NKGRSMVHKE 240 AWLISAKQEL FLYQTYPEIL SVFPKVGSLG GRTDIIITGD FFDPSARVTI AGIPCDIRYV 300 SPRKIECTTR APGNEARLTA PQAGNRGLRF EVGDATKDVE LTEATPGYRW QIVPNASSPS 360 GFWSKEGRPF RARLSGFFVA PQTNNYTFWI QADSQASLCF SSSEEPRTKV EVASVGVGTA 420 DWFDSWEQIG NEGSWHQKTT KLELQGGAKY YLEAEQHGIA PSRGMRIGVQ IHNTWLNPDV 480 VNTYLLEKHQ IRARAQRLPE IQVLHVSGKG NFFLTWGNVS SQPVPANATA QQIQTTIEEL 540 LVVKCNLAPF SAHVLLRLGF EQGLEGSRSD GVRTSSTEPF CGRFSLGQLG HLILIPEAAD 600 KGYQLDRYPY LCLAYRGHMN KTLDMTVSFL FGFQTIMKNI TCDWSLTDPH PESWQFTCIN 660 LWDTCLCHSE DIQSSLANTP LLAHRIDIRP VVPEAGLLYV DEIILADTNV TVSQADSGRA 720 CPGGNVVESV SVVGVPPVYS ISSWLAGCGS ELPLITACSV STEGTGDGSE LIEVTAQRLQ 780 RTSPPLGGHF FLYLSDTVIP DVPVRMSARQ LHKLLQDSAD ESTSGYLNAG DFTVTEDLNS 840 CYEHVWTLSW TTQTGDLPNF IRVSDQNLTG VNPTVTARVV YDGGVFLGPI FGDMLATANQ 900 QTQVAVQVND IPAYCSGSCS FQYQQESTPS VDHVWYSLGS DVNLLVHFTG TGFPRDTQFL 960 QVTVNKTSCE VLFSNETNVA CELALLPVGV HQIFMLVIPS GLAVHASGED LLLHVEPRLD 1020 AVEPSTAAEI GGRWVTLRGS SLEGVSLVLF GTQSCVIDAI RSNSQQIQCK VPPRGKDGYT 1080 VNVTVISGDH STVLARAFTY VSSLNPVIVS LSRNRSSIAG GEILFLGMSL LVNYTDLDVQ 1140 IHVQDTSAQV LSQTAWGLEV VLPPLVPGIH VISAFINGVS IRSQGVDLYI QYLTEVFSVE 1200 PCSGSLLGGT LLSLLGTGLG RDPALIRVLV DNHPCDIVNL TEVNIWCETP PAVLPPRADV 1260 LTVLASVEIW AGNTSFFHGP SLVGKGFTFT YEAAATPVVT AMWGEFRNNS VRFYVEGSNI 1320 SDSVILLGSL KCELEVQFFG DSMNLSGCFF PLHSLEAGVY TLQVRHKRMG FANMSVVPQK 1380 FELSPQIIAI FPTHGSKCGG TVLTVKGMAF SSRKRSVHVD ISGPFACMIL SLEDHTVLCQ 1440 TRFVGDQFSE ASLALNITVL VNGLTSKCKG NCTLFIEEAA TPIVDALTIS ISGSLTMVLM 1500 RGRRLATTAD EPIAFVDDQL PCHTTFFNTS HVACQIRDLA PGFHYLSAVH TSAGYACLNS 1560 VSRNFFIVPQ VLDYFPKDFS IHGGSLLTIK GTALRGWKAT VVYVGRQACL TVNFSSDFIQ 1620 CIVPAGNGSA ALEIDVNGVL YHIGLVDYSS IFTPELLSVS RSQDILTFTV ARISGAANVD 1680 IFIGTSPCLG VAGNRTVLQC MVPLLPAGEY LVTGYDHSRG WASSTLILVL RATVTSVTKN 1740 YGCLGGRLLH VLGAGFSPGN ISAAVCGAPC QVLANATVSA FSCLVLPLHV SLAFLCDLRH 1800 AEDSCKVRSS TYLRCDLTVS MGTERLPGSW PYVYLCEESS LCLFEPDHWT ESVFPSFSGL 1860 FLSPKVERDE VLIYNSSCNI TMETEAEMEC EMPNQPITAK ITEIQKSWGQ NTQGNFSFQF 1920 CRRWSRPHSW FPQRVPHDGD SVTVETGHLL LLDANTSFLN SLHIKGGKLI FMDPGPIELR 1980 AHSILITDGG ELHIGSEEKP FQGKARIKIY GSVHSTPFFP YGVKFLAVRN GTLSLHGSVP 2040 EVTVTYLQAA AHAGDKVLTL GEAVDWKPGD EAVITSGMTV AGAEATEVVV VETVHNADLH 2100 LRNPLRYSYD FRENWVAGEN PILKPTVALL SRNIIIQGNF TLERVKLLNS CQEANTAKGN 2160 LKHCLYSKSE KMLGARDLGA RVIIQSFPEE PSFVKLKGVQ FRDLGQAFHK HLSSLALVGA 2220 MRGSYIQSCS VWNSFSRGLS MHRTWGLKVD SNVFYKIVGH ALLLGSYLDG RFSTSETVTG 2280 RKNGWWEQGS TIRNNVIISV SAAEGLSGSE MLAPAGIYTF SPTNVMEGNR VCAAGYGYVF 2340 HLVTSQTLQA PLLSFNWNTA HSCTRYGLLV YPKFQPPWNN DTGFTLFQNF MVWGSAGGAQ 2400 IFRSNNLHLK NFQVYACRDF GIDILESDAN TLITDSFLLG HFTHKGSLCM SAGIKTPQRW 2460 ELTISNTTFV NFDGNCVAIR TCSGCFQGQG GYTVKTRQLK FVNSSNLVAF PFPHAAVLED 2520 LDGSLSGKNG SHVLASMETL SDTCLTNASF SQIVPGSVCG EAVLFHRMSI ALANSLDVPK 2580 NLTITDISNK TITVNYVEDT LSNYYGWMAL LLDQETYSLQ FESPWMNRSL QYSATFDSFA 2640 PGNYLLIMHR DLPPYPDILL RCGSQVGHSL PFHPLPSQDR ACDWFFNRQL RQLTYLVSGE 2700 GQVKVFLQLK PGVPPSVSAS TSVPESASRW SLPETWQDVE KGWGGYNHTI PGPGDDVLIL 2760 PNKTVLVDTD LPVLRCLYVM GTLEFPVDRS NVLSVACLLI AGGELKVGTL ENPLEKDQRL 2820 LIFLRASEEV VCDYFEGIHV DPGTIGVYGK LRLHSAYPKK SWVHLGADIA PGNERIIVHN 2880 AVDWQPHDTI VLSSSSYEAH EAEVLTVKEV KGHHIRIYER LKHRHIGSTH TMEDGQQVHL 2940 AAEVGLLTRN IRIQPDSSCR GRLLVGSFRK SSGEDFSGVL QLLNVEIQNM GLPLYSSIEF 3000 TGVSAGSWVI SSTVHQSCSV GIHASSSHGV ILTDNVVFGT NGHGIDVEGQ NYSLTNNLVI 3060 LTMQSANSSP WVAGIKVNYA EDIILHGNVV AGSERLGFHV GGHGCSSEVL WSDNVVHSSL 3120 HGLHLYKKHE SNNCTGVSGF MAFKNFDYGA MVQTENSVDI QNITLVDNTV GLLAITYVSS 3180 ALLSSVSTVQ ITLRNSVIVA TSSSFDCIHD RKAPQSANWT STDRAPSNPR GGRIGILWPV 3240 SASEPNAWPQ EPWHKVRSRH SVPGIMKLQD VTFSSFVKSC YSNDLDVCIL PNEYSTGVMY 3300 PITAERTRML GIKDKNKFYF PVLQSSKDLV GTICPTLVCE YPRKYLFTDL DGRTLGLPPP 3360 VSVFPRTEEE WTGSFLNTGI FREEQKCTFR AMNQGFFCKQ TEHAVLILDN VDATWTIPKS 3420 HPLVSVTNGF VDTFSIVKDS DLCPPTSSLS TFYSILPTRQ MTKVCFPEQT PPFLRFLLLG 3480 NQRASKLILA VFYNEIQSPH VFLDKSFIPP TPLESAFSLL AEPSGANYFD IMNNLLYVVL 3540 QGEEPVEIHS SVSIHLALTV TFSVLEKGWE RAMLESLSDF FQIDPNQIRL TLEMPGNKET 3600 LEAIANSERK RKRNCPSVTC GGPSIRYGQR RPLMAEMTSL KITPATTLET FSKVIVIEVG 3660 DLPNIRNSEP IQSLPSNRLQ RLVNQVITAQ QTGALENVLG MTVGALLVTQ SKGVTGYRNA 3720 SSLITGNLIY TRPSELSILV QPSDGEVGIE LPVQPRLVFL DEKNERVESL GLPSEPWIIS 3780 VSLEGASESV LKGCTLAETR DGYVTFSRLA VLISGSNWHL FFTVISPPGT NFTARSRTFV 3840 VLPVASKERS TIILALSLCS VASWVALSCL VCCWFKKSKT RKIKPEDISE SQAKEQKKNT 3900 HNSSKPRGLQ AKTAKENTLM GEDMRMKVMQ GMQSQFPQHS MDGVSKRKVS RLAVTEERTT 3960 TPAPKIPRIT CVPGSLAQQL TLQEPGNWQE AQQQLLRYQL AGRNQLLLLR PDLRQERKQG 4020 QEPSQLDKGS DCTGLSQEKA TCIPTETFSL HTAPPETIQ
Fasta Sequence
>E9PZ36|Pkhd1|Mus musculus(Mouse) MMLAWLVSLLSMEVLLLAKPYSSFQFEPAEGSLAGGTWITVVFDGLDRSILYPNNGSQLQIDLVSVAIPTLRIPCDVSPAFVDLPVVTCQTRSLPSEADAGPYSLEMRSGEQVLGTPCPGSLDSCTFKFSKDQTPVLYQVYPASGVPGEVVSVYGRVITTWLETFDPDVDYIESPLILEAREDKWLTPCSLINRQTGSCFPIQEEHGLGNVQCRVEGDYIGSQNVSFSVFNKGRSMVHKEAWLISAKQELFLYQTYPEILSVFPKVGSLGGRTDIIITGDFFDPSARVTIAGIPCDIRYVSPRKIECTTRAPGNEARLTAPQAGNRGLRFEVGDATKDVELTEATPGYRWQIVPNASSPSGFWSKEGRPFRARLSGFFVAPQTNNYTFWIQADSQASLCFSSSEEPRTKVEVASVGVGTADWFDSWEQIGNEGSWHQKTTKLELQGGAKYYLEAEQHGIAPSRGMRIGVQIHNTWLNPDVVNTYLLEKHQIRARAQRLPEIQVLHVSGKGNFFLTWGNVSSQPVPANATAQQIQTTIEELLVVKCNLAPFSAHVLLRLGFEQGLEGSRSDGVRTSSTEPFCGRFSLGQLGHLILIPEAADKGYQLDRYPYLCLAYRGHMNKTLDMTVSFLFGFQTIMKNITCDWSLTDPHPESWQFTCINLWDTCLCHSEDIQSSLANTPLLAHRIDIRPVVPEAGLLYVDEIILADTNVTVSQADSGRACPGGNVVESVSVVGVPPVYSISSWLAGCGSELPLITACSVSTEGTGDGSELIEVTAQRLQRTSPPLGGHFFLYLSDTVIPDVPVRMSARQLHKLLQDSADESTSGYLNAGDFTVTEDLNSCYEHVWTLSWTTQTGDLPNFIRVSDQNLTGVNPTVTARVVYDGGVFLGPIFGDMLATANQQTQVAVQVNDIPAYCSGSCSFQYQQESTPSVDHVWYSLGSDVNLLVHFTGTGFPRDTQFLQVTVNKTSCEVLFSNETNVACELALLPVGVHQIFMLVIPSGLAVHASGEDLLLHVEPRLDAVEPSTAAEIGGRWVTLRGSSLEGVSLVLFGTQSCVIDAIRSNSQQIQCKVPPRGKDGYTVNVTVISGDHSTVLARAFTYVSSLNPVIVSLSRNRSSIAGGEILFLGMSLLVNYTDLDVQIHVQDTSAQVLSQTAWGLEVVLPPLVPGIHVISAFINGVSIRSQGVDLYIQYLTEVFSVEPCSGSLLGGTLLSLLGTGLGRDPALIRVLVDNHPCDIVNLTEVNIWCETPPAVLPPRADVLTVLASVEIWAGNTSFFHGPSLVGKGFTFTYEAAATPVVTAMWGEFRNNSVRFYVEGSNISDSVILLGSLKCELEVQFFGDSMNLSGCFFPLHSLEAGVYTLQVRHKRMGFANMSVVPQKFELSPQIIAIFPTHGSKCGGTVLTVKGMAFSSRKRSVHVDISGPFACMILSLEDHTVLCQTRFVGDQFSEASLALNITVLVNGLTSKCKGNCTLFIEEAATPIVDALTISISGSLTMVLMRGRRLATTADEPIAFVDDQLPCHTTFFNTSHVACQIRDLAPGFHYLSAVHTSAGYACLNSVSRNFFIVPQVLDYFPKDFSIHGGSLLTIKGTALRGWKATVVYVGRQACLTVNFSSDFIQCIVPAGNGSAALEIDVNGVLYHIGLVDYSSIFTPELLSVSRSQDILTFTVARISGAANVDIFIGTSPCLGVAGNRTVLQCMVPLLPAGEYLVTGYDHSRGWASSTLILVLRATVTSVTKNYGCLGGRLLHVLGAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLHVSLAFLCDLRHAEDSCKVRSSTYLRCDLTVSMGTERLPGSWPYVYLCEESSLCLFEPDHWTESVFPSFSGLFLSPKVERDEVLIYNSSCNITMETEAEMECEMPNQPITAKITEIQKSWGQNTQGNFSFQFCRRWSRPHSWFPQRVPHDGDSVTVETGHLLLLDANTSFLNSLHIKGGKLIFMDPGPIELRAHSILITDGGELHIGSEEKPFQGKARIKIYGSVHSTPFFPYGVKFLAVRNGTLSLHGSVPEVTVTYLQAAAHAGDKVLTLGEAVDWKPGDEAVITSGMTVAGAEATEVVVVETVHNADLHLRNPLRYSYDFRENWVAGENPILKPTVALLSRNIIIQGNFTLERVKLLNSCQEANTAKGNLKHCLYSKSEKMLGARDLGARVIIQSFPEEPSFVKLKGVQFRDLGQAFHKHLSSLALVGAMRGSYIQSCSVWNSFSRGLSMHRTWGLKVDSNVFYKIVGHALLLGSYLDGRFSTSETVTGRKNGWWEQGSTIRNNVIISVSAAEGLSGSEMLAPAGIYTFSPTNVMEGNRVCAAGYGYVFHLVTSQTLQAPLLSFNWNTAHSCTRYGLLVYPKFQPPWNNDTGFTLFQNFMVWGSAGGAQIFRSNNLHLKNFQVYACRDFGIDILESDANTLITDSFLLGHFTHKGSLCMSAGIKTPQRWELTISNTTFVNFDGNCVAIRTCSGCFQGQGGYTVKTRQLKFVNSSNLVAFPFPHAAVLEDLDGSLSGKNGSHVLASMETLSDTCLTNASFSQIVPGSVCGEAVLFHRMSIALANSLDVPKNLTITDISNKTITVNYVEDTLSNYYGWMALLLDQETYSLQFESPWMNRSLQYSATFDSFAPGNYLLIMHRDLPPYPDILLRCGSQVGHSLPFHPLPSQDRACDWFFNRQLRQLTYLVSGEGQVKVFLQLKPGVPPSVSASTSVPESASRWSLPETWQDVEKGWGGYNHTIPGPGDDVLILPNKTVLVDTDLPVLRCLYVMGTLEFPVDRSNVLSVACLLIAGGELKVGTLENPLEKDQRLLIFLRASEEVVCDYFEGIHVDPGTIGVYGKLRLHSAYPKKSWVHLGADIAPGNERIIVHNAVDWQPHDTIVLSSSSYEAHEAEVLTVKEVKGHHIRIYERLKHRHIGSTHTMEDGQQVHLAAEVGLLTRNIRIQPDSSCRGRLLVGSFRKSSGEDFSGVLQLLNVEIQNMGLPLYSSIEFTGVSAGSWVISSTVHQSCSVGIHASSSHGVILTDNVVFGTNGHGIDVEGQNYSLTNNLVILTMQSANSSPWVAGIKVNYAEDIILHGNVVAGSERLGFHVGGHGCSSEVLWSDNVVHSSLHGLHLYKKHESNNCTGVSGFMAFKNFDYGAMVQTENSVDIQNITLVDNTVGLLAITYVSSALLSSVSTVQITLRNSVIVATSSSFDCIHDRKAPQSANWTSTDRAPSNPRGGRIGILWPVSASEPNAWPQEPWHKVRSRHSVPGIMKLQDVTFSSFVKSCYSNDLDVCILPNEYSTGVMYPITAERTRMLGIKDKNKFYFPVLQSSKDLVGTICPTLVCEYPRKYLFTDLDGRTLGLPPPVSVFPRTEEEWTGSFLNTGIFREEQKCTFRAMNQGFFCKQTEHAVLILDNVDATWTIPKSHPLVSVTNGFVDTFSIVKDSDLCPPTSSLSTFYSILPTRQMTKVCFPEQTPPFLRFLLLGNQRASKLILAVFYNEIQSPHVFLDKSFIPPTPLESAFSLLAEPSGANYFDIMNNLLYVVLQGEEPVEIHSSVSIHLALTVTFSVLEKGWERAMLESLSDFFQIDPNQIRLTLEMPGNKETLEAIANSERKRKRNCPSVTCGGPSIRYGQRRPLMAEMTSLKITPATTLETFSKVIVIEVGDLPNIRNSEPIQSLPSNRLQRLVNQVITAQQTGALENVLGMTVGALLVTQSKGVTGYRNASSLITGNLIYTRPSELSILVQPSDGEVGIELPVQPRLVFLDEKNERVESLGLPSEPWIISVSLEGASESVLKGCTLAETRDGYVTFSRLAVLISGSNWHLFFTVISPPGTNFTARSRTFVVLPVASKERSTIILALSLCSVASWVALSCLVCCWFKKSKTRKIKPEDISESQAKEQKKNTHNSSKPRGLQAKTAKENTLMGEDMRMKVMQGMQSQFPQHSMDGVSKRKVSRLAVTEERTTTPAPKIPRITCVPGSLAQQLTLQEPGNWQEAQQQLLRYQLAGRNQLLLLRPDLRQERKQGQEPSQLDKGSDCTGLSQEKATCIPTETFSLHTAPPETIQ
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Keyword |
KW-0181--Complete proteome KW-0472--Membrane KW-1185--Reference proteome KW-0732--Signal KW-0812--Transmembrane KW-1133--Transmembrane helix
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Interpro |
IPR019316--G8_domain IPR013783--Ig-like_fold IPR014756--Ig_E-set IPR002909--IPT IPR006626--PbH1 IPR012334--Pectin_lyas_fold IPR011050--Pectin_lyase_fold/virulence IPR028839--PKHD1
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PROSITE |
PS51484--G8
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Pfam |
PF10162--G8 PF01833--TIG
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Gene Ontology |
GO:0016324--C:apical plasma membrane GO:0005813--C:centrosome GO:0036064--C:ciliary basal body GO:0005737--C:cytoplasm GO:0070062--C:extracellular exosome GO:0016021--C:integral component of membrane GO:0072686--C:mitotic spindle GO:0048471--C:perinuclear region of cytoplasm GO:0072372--C:primary cilium GO:0006874--P:cellular calcium ion homeostasis GO:0042384--P:cilium assembly GO:0001822--P:kidney development GO:0043066--P:negative regulation of apoptotic process GO:0032088--P:negative regulation of NF-kappaB transcription factor activity GO:0051898--P:negative regulation of protein kinase B signaling GO:0008284--P:positive regulation of cell proliferation GO:0010824--P:regulation of centrosome duplication GO:0070372--P:regulation of ERK1 and ERK2 cascade GO:0032006--P:regulation of TOR signaling
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