dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050738
Uniprot Accession E9PYT0; E9PYT0_MOUSE;
Genbank Protein ID NP_033836.2; XP_006515501.1; XP_011242291.1; XP_011242292.1;
Genbank Nucleotide ID NM_009706.2; XM_006515438.2; XM_011243989.1; XM_011243990.1;
Protein Name Rho GTPase-activating protein 5
Protein Synonyms/Alias
Gene Name Arhgap5
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
1125RIIKIRNSFVNNTQGcurated23684622
1172AKSYYRRTHSDASDDcurated23684622
1174SYYRRTHSDASDDEAPHOSIDA;PhosphoSitePlus;SysPTM 2.0;curated21081558; 22135298; 18846507; 19366988; 23684622; 22817900;
1177RRTHSDASDDEAFTTPHOSIDA;PhosphoSitePlus;SysPTM 2.0;curated21081558; 22135298; 18846507; 19366988; 23684622; 22817900;
Sequence
(Fasta)		MMAKNKEPRP PSYTVSVVGL SGTEKDKGNC GVGKSCLCNR FVRSKADEYY PEHTSVLSTI 60
DFGGRVVNND HFLYWGDITQ NGEDGVECKI HVIEQTEFID DQTFLPHRST NLQPYIKRAA 120
ASKLQSAEKL MYICTDQLGL EQDFEQKQMP EGKLNVDGFL LCIDVSQGCN RKFDDQLKFV 180
NNLFVQLSKS KKPVIIAATK CDECVDHYLR EVQAFASNKK NLLVVETSAR FNVNIETCFT 240
ALVQMLDKTR GKPKIIPYLD AYKTQRQLVV TATDKFEKLV QTVRDYHATW KTVSNKLKNH 300
PDYEEYINLE GTRKARNTFS KHIEQLKQEH IRKRREEYIS TLPRAFNTLL PDLEEIEHLN 360
WLEALKLMEK RADFQLCFVV LEKTPWDETD HIDKINDRRI PFDLLSTLEA EKVYQNHVQH 420
LISEKRRIEM KEKFKKTLEK IQFISPGQPW EEVMCFVMED EAFKYITEAD SKEVYGRHQR 480
EIVEKAKEEF QEMLFEHSEL FYDLDLNATP SSDKMSEIHT VLSEEPRYKA LQKLAPDRES 540
LLLKHIGFVY HPTKETCLSG QYCTDIKVEN LLATSLLEMD HNRVRLYHDS TNIDKVNLFI 600
LGKDGLAQEL ANEIRTQSTD DEYALDGKIY ELDLRPVDAK SPYILSQLWT AAFKPHGCFC 660
VFNSIESLSF IGEFIGKIRT EASQIRKDKY MTNLPFTLIL ANQRDSISKN LPILRHQGQQ 720
LANKLQCPFV DVPTGTYPRK FNESQIKQAL RGVLESVKHN LDVVSPVPIN KDVSEADLRI 780
VMCAMCGDPF SVDLILSPFL DSHSCSAAQA GQNNSLMLDK IIGEKRRRIQ ITILSYHSSI 840
GVRKDELVHG YILVYSAKRK ASMGMLRAFL SEVQDTIPVQ LVAVTDSQAD FFENEAIKEL 900
MTEGEHIATE ITAKFTALYS LSQYHRQTEV FTLFFSDVLE KKNMIENSYL SDNTRESTHQ 960
SEDVFLPSPR DCFPYNNYPD SDDDTEAPPP YSPIGDDVQL LPTPSDRSRY RLDLEGNEYP 1020
VHSTPNCHDH ERNHKVPPPI KPKPVVPKTN VKKLDPNLLK TIEAGIGKNP RKQTSRVPLA 1080
HPEDMDSSDN YVEPLDTIFK QKGYSDEIYV VPDDSQNRII KIRNSFVNNT QGDEENGFSD 1140
RTSKGHGERR PSKYKYKSKT LFSKAKSYYR RTHSDASDDE AFTTSKTKRK GRHRGSEEDP 1200
LLSPVETWKG GIDNPAITSD QEVDDKKIKK KTHKVKEDKK QKKKTKTFNP PTRRNWESNY 1260
FGMPLQDLVT AEKPIPLFVE KCVEFIEDTG LCTEGLYRVS GNKTDQDNIQ KQFDQDHNIN 1320
LASMEVTVNA VAGALKAFFA DLPDPLIPYS LHPELLEAAK IPDKTERFHA LKEIVKKFHP 1380
VNYDVFRYVI THLNRVSQQN KINLMTADNL SICFWPTLMR PDFENREFLS TTKIHQSVVE 1440
TFIQQCQFFF YNGEIVETAN TVAPPPTSNP GQLVESMVPL QLPPPLQPQL IQPQLQTDPL 1500
GII 1504
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR002713--FF_domain
IPR027417--P-loop_NTPase
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001806--Small_GTPase
PROSITE

PS51676--FF
PS50238--RHOGAP
Pfam

PF01846--FF
PF00071--Ras
PF00620--RhoGAP
Gene Ontology

GO:0005622--C:intracellular
GO:0005525--F:GTP binding
GO:0042169--F:SH2 domain binding
GO:0030335--P:positive regulation of cell migration
GO:0002053--P:positive regulation of mesenchymal cell proliferation
GO:0008361--P:regulation of cell size
GO:0007264--P:small GTPase mediated signal transduction