dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050723
Uniprot Accession E9PYG6; E9PYG6_MOUSE;
Genbank Protein ID NP_663427.2;
Genbank Nucleotide ID NM_145452.3;
Protein Name Protein Rasa1
Protein Synonyms/Alias
Gene Name Rasa1
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 12
PositionPeptidesSourceReferences ( PMIDs )
155DSLDGPEYEEEEVAIPhosphoSitePlus22135298
409MGGRYYNSIGDIIDHPhosphoSitePlus;curated22135298; 22817900; 21183079
451TVDGKEIYNTIRRKTPhosphoSitePlus;SysPTM 2.022135298; 18515860; 19366988
463RKTKDAFYKNIVKKGPhosphoSitePlus;SysPTM 2.022135298; 18515860; 19366988
568KGLQAFCSLRKSSPGPHOSIDA;PhosphoSitePlus21081558; 22135298
573FCSLRKSSPGTSNKRPhosphoSitePlus22135298
576LRKSSPGTSNKRLRQPhosphoSitePlus22135298
606VKHFTNPYCNIYLNSPhosphoSitePlus22135298
714KIMPEEEYSEFKELIPhosphoSitePlus22135298
715IMPEEEYSEFKELILPhosphoSitePlus22135298
822SKQSCELSPSKLEKNcurated25338131
943EFGAKEPYMEGVNPFPhosphoSitePlus22135298
Sequence
(Fasta)		MMAAEAGSEE GGPATAGPGG GAATGSSAYS AACRVKLPAA LPVAAAPCPG LADADLVAAL 60
GGGAASGSGF LGTGPVAGVL GGAALTGSAA AGVAGAAAAG PAGDVAFTKG TLSLPAETLG 120
PGGGFPPLPP PPQLPPLGSG LGTVDEGDSL DGPEYEEEEV AIPLTAPPTN QWYHGKLDRT 180
IAEERLRQAG KSGSYLIRES DRRPGSFVLS FLSQTNVVNH FRIIAMCGDY YIGGRRFSSL 240
SDLIGYYSHV SCLLKGEKLL YPVAPPEPVE DRRRVRAILP YTKVPDTDEI SFLKGDMFIV 300
HNELEDGWMW VTNLRTDEQG LIVEDLVEEV GREEDPHEGK IWFHGKISKQ EAYNLLMTVG 360
QVCSFLVRPS DNTPGDYSLY FRTNENIQRF KICPTPNNQF MMGGRYYNSI GDIIDHYRKE 420
QIVEGYYLKE PVPMQDQGQV LNDTVDGKEI YNTIRRKTKD AFYKNIVKKG YLLKKGKGKR 480
WKNLYFILEG SDAQLIYFES EKRATKPKGL IDLSVCSVYV VHDSLFGRPN CFQIVVQHFS 540
EEHYIFYFAG ETPEQAEDWM KGLQAFCSLR KSSPGTSNKR LRQVSSLVLH IEEAHKLPVK 600
HFTNPYCNIY LNSVQVAKTH AREGQNPVWS EEFVFDDLPP DINRFEITLS NKTKKSKDPD 660
ILFMRCQLSR LQKGHATDEW FLLSSHIPLK GIEPGSLRVR ARYSMEKIMP EEEYSEFKEL 720
ILQKELHVVY ALSHVCGQDR TLLASILLKI FLHEKLESLL LCTLNDREIS MEDEATTLFR 780
ATTLASTLME QYMKATATQF VHHALKDSIL KIMESKQSCE LSPSKLEKNE DVNTNLAHLL 840
SILSELVEKI FMASEILPPT LRYIYGCLQK SVQHKWPTNN TMRTRVVSGF VFLRLICPAI 900
LNPRMFNIIS DSPSPIAART LTLVAKSVQN LANLVEFGAK EPYMEGVNPF IKSNKHRMIM 960
FLDELGNVPE LPDTTEHSRT DLSRDLAALH EICVAHSDEL RTLSNERGVQ QHVLKKLLAI 1020
TELLQQKQNQ YTKTNDIR 1039
Keyword

KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
Interpro

IPR000008--C2_dom
IPR028554--p120-RasGAP
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR023152--RasGAP_CS
IPR001936--RasGAP_dom
IPR008936--Rho_GTPase_activation_prot
IPR000980--SH2
IPR001452--SH3_domain
PROSITE

PS50004--C2
PS50003--PH_DOMAIN
PS00509--RAS_GTPASE_ACTIV_1
PS50018--RAS_GTPASE_ACTIV_2
PS50001--SH2
PS50002--SH3
Pfam

PF00168--C2
PF00169--PH
PF00616--RasGAP
PF00017--SH2
PF00018--SH3_1
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0031235--C:intrinsic component of the cytoplasmic side of the plasma membrane
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0001948--F:glycoprotein binding
GO:0005096--F:GTPase activator activity
GO:0051020--F:GTPase binding
GO:0005102--F:receptor binding
GO:0048514--P:blood vessel morphogenesis
GO:0007162--P:negative regulation of cell adhesion
GO:0001953--P:negative regulation of cell-matrix adhesion
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0043547--P:positive regulation of GTPase activity
GO:0030833--P:regulation of actin filament polymerization
GO:0007165--P:signal transduction