| Tag |
Content |
| dbPAF ID |
dbPAF-0050708 |
| Uniprot Accession |
E9PXY8; E9PXY8_MOUSE;
|
| Genbank Protein ID |
XP_006522201.1;
|
| Genbank Nucleotide ID |
XM_006522138.2;
|
| Protein Name |
Ubiquitin carboxyl-terminal hydrolase |
| Protein Synonyms/Alias |
|
| Gene Name |
Usp7 |
| Gene Synonyms/Alias |
|
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 6 | --MASSTSPPRSPSG | curated | 25521595 |
|
Sequence
(Fasta) | MASSTSPPRS PSGRILTQDT IYFPQSNIIS ELLPWYLRYT PPEVPSTSVI TKFILVNCPW 60
NEGIEYQAGD TDDPPRITQN PVINGNVTLS DGHSNAEEDM EDDTSWRSEA TFQFTVERFS 120
RLSESVLSPP CFVRNLPWKI MVMPRFYPDR PHQKSVGFFL QCNAESDSTS WSCHAQAVLK 180
IINYRDDDKS FSRRISHLFF HKENDWGFSN FMAWSEVTDP EKGFIDDDKV TFEVFVQADA 240
PHGVAWDSKK HTGYVGLKNQ GATCYMNSLL QTLFFTNQLR KAVYMMPTEG DDSSKSVPLA 300
LQRVFYELQH SDKPVGTKKL TKSFGWETLD SFMQHDVQEL CRVLLDNVEN KMKGTCVEGT 360
IPKLFRGKMV SYIQCKDVDY RSDRREDYYD IQLSIKGKKN IFESFVDYVA VEQLDGDNKY 420
DAGEHGLQEA EKGVKFLTLP PVLHLQLMRF MYDPQTDQNI KINDRFEFPE QLPLDEFLQK 480
TDPKDPANYI LHAVLVHSGD NHGGHYVVYL NPKGDGKWCK FDDDVVSRCT KEEAIEHNYG 540
GHDDDLSVRH CTNAYMLVYI RESKLSEVLQ AVTDHDIPQQ LVERLQEEKR IEAQKRKERQ 600
EAHLYMQVQI VAEDQFCGHQ GNDMYDEEKV RYTVFKVLKN SSLAEFVQSL SQTMGFPQDQ 660
IRLWPMQARS NGTKRPAMLD NEADGNKTMI ELSDNENPWT IFLETVDPEL AASGATLPKF 720
DKDHDVMLFL KMYDPKTRSL NYCGHIYTPI SCKIRDLLPV MCDRAGFIQD TSLILYEEVK 780
PNLTERIQDY DVSLDKALDE LMDGDIIVFQ KDDPENDNSE LPTAKEYFRD LYHRVDVIFC 840
DKTIPNDPGF VVTLSNRMNY FQVAKTVAQR LNTDPMLLQF FKSQGYRDGP GNPLRHNYEG 900
TLRDLLQFFK PRQPKKLYYQ QLKMKITDFE NRRSFKCIWL NSQFREEEIT LYPDKHGCVR 960
DLLEECKKAV ELGDKASGRL RLLEIVSYKI IGVHQEDELL ECLSPATSRT FRIEEIPLDQ 1020
VDIDKENEML ITVAHFHKEV FGTFGIPFLL RIHQGEHFRE VMKRIQSLLD IQEKEFEKFK 1080
FAIVMMGRHQ YINEDEYEVN LKDFEPQPGN MSHPRPWLGL DHFNKAPKRS RYTYLEKAIK 1140
IHN
1144Fasta Sequence
>E9PXY8|Usp7|Mus musculus(Mouse)
MASSTSPPRSPSGRILTQDTIYFPQSNIISELLPWYLRYTPPEVPSTSVITKFILVNCPWNEGIEYQAGDTDDPPRITQNPVINGNVTLSDGHSNAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDDKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKDVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVRYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGDKASGRLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLITVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN
|
| Keyword |
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
|
| Interpro |
IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom
|
| PROSITE |
PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
|
| Pfam |
PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0005634--C:nucleus
GO:0004197--F:cysteine-type endopeptidase activity
GO:0002039--F:p53 binding
GO:0008022--F:protein C-terminus binding
GO:0008134--F:transcription factor binding
GO:0031625--F:ubiquitin protein ligase binding
GO:0004843--F:ubiquitin-specific protease activity
GO:0016578--P:histone deubiquitination
GO:0010216--P:maintenance of DNA methylation
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0061136--P:regulation of proteasomal protein catabolic process
GO:0051090--P:regulation of sequence-specific DNA binding transcription factor activity
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006283--P:transcription-coupled nucleotide-excision repair
|
