dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050695
Uniprot Accession E9PXF0; E9PXF0_MOUSE;
Genbank Protein ID NP_001013775.2;
Genbank Nucleotide ID NM_001013753.2;
Protein Name Protein Pcdh17
Protein Synonyms/Alias
Gene Name Pcdh17
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
806QTRLPLSSPRSEVMYcurated21183079; 22807455
888ERASLRDSGHGDSDQPhosphoSitePlus;curated22135298; 22817900; 21183079
893RDSGHGDSDQADSDQPhosphoSitePlus;curated22135298; 22817900; 21183079
898GDSDQADSDQDTNKGPhosphoSitePlus;curated22135298; 22817900; 21183079
1032PLLQEVPSASSSPTKcurated21183079; 22807455
1035QEVPSASSSPTKACIcurated21183079
1036EVPSASSSPTKACIEPHOSIDA;PhosphoSitePlus21081558; 22135298
1109HSRARRASSEMGAVLPhosphoSitePlus;curated22135298; 22817900; 21183079; 25521595
1110SRARRASSEMGAVLEcurated22807455
Sequence
(Fasta)
MYLSICCCFL LWAPALTLKN LNYSVPEEQG AGTVIGNIGK DARLQPGLPP AERGSGSGRS 60
KSGSYRVLEN SAPHLLDVDA DSGLLYTKQR IDRESLCRHN AKCQLSLEVF ANDKEICMIK 120
VEIQDINDNA PSFPSDQIEM DISENAAPGT RFPLTSAHDP DAGENGLRTY LLTRDDHGLF 180
ALDVKSRGDG TKFPELVIQK ALDRELQNHH TLVLTALDGG EPPRSATVQI NVKVIDSNDN 240
SPVFEAPSYL VELPENAPLG TVVIDLNATD ADEGPNGEVL YSFSSYVPDR VRELFSIDPK 300
TGLIRVKGNL DYEENGMLEI DVQARDLGPN PIPAHCKVTV KLIDRNDNAP SIGFVSVRQG 360
ALSEAAPPGT VIALVRVTDR DSGKNGQLQC RVLGGGGTGG GLGGPGSVPF KLEENYDNFY 420
TVVTDRPLDR ETQDEYNVTI VARDGGSPPL NSTKSFAVKI LDENDNPPRF TKGLYVLQVH 480
ENNIPGEYLG SVLAQDPDLG QNGTVSYSIL PSHIGDVSIY TYVSVNPTNG AIYALRSFNY 540
EQTKAFEFKV LAKDSGAPAH LESNATVRVT VLDVNDNAPV IVLPTLQNDT AELQVPRNAG 600
LGYLVSTVRA LDSDFGESGR LTYEIVDGND DHLFEIDPSS GEIRTLHPFW EDVTPVVELV 660
VKVTDHGKPT LSAVAKLIIR SVSGSLPEGV PRVNGEQHHW DMSLPLIVTL STISIILLAA 720
MITIAVKCKR ENKEIRTYNC RIAEYSHPQL GGGKGKKKKI NKNDIMLVQS EVEERNAMNV 780
MNVVSSPSLA TSPMYFDYQT RLPLSSPRSE VMYLKPASNN LTVPQGHAGC HTSFTGQGTN 840
SSETPATRMS IIQTDNFPAE PNYMGSRQQF VQSSSTFKDP ERASLRDSGH GDSDQADSDQ 900
DTNKGSCCDM SVREALKMKT TSTKSQPLEQ EPEECINCTD ECRVLGHSDR CWMPQFPAAN 960
QAENADYRTN LFVPTVEANV ETETYETVNP TGKKTFCTFG KDKREHTILI ANVKPYLKAK 1020
RALSPLLQEV PSASSSPTKA CIEPCASTKG SLDGCEAKPG PLAEASSSYL PTDSQYPSPS 1080
KQPRDPSFMA SDQMARVFAD VHSRARRASS EMGAVLEQLE QPNRDLGRES VDAEEVVREI 1140
DKLLQDCRGN DPVAVRK 1158
Keyword

KW-0106--Calcium
KW-0130--Cell adhesion
KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR002126--Cadherin
IPR015919--Cadherin-like
IPR020894--Cadherin_CS
IPR013164--Cadherin_N
IPR030709--Protocadherin-17

PROSITE

PS00232--CADHERIN_1
PS50268--CADHERIN_2

Pfam

PF00028--Cadherin
PF08266--Cadherin_2

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0030534--P:adult behavior
GO:0007156--P:homophilic cell adhesion via plasma membrane adhesion molecules
GO:0050805--P:negative regulation of synaptic transmission
GO:1904071--P:presynaptic active zone assembly
GO:2000807--P:regulation of synaptic vesicle clustering