dbPAF - database of Phospho-sites in Animals and Fungi

Protein
Gene
PTMs
Sequence
Keyword
GO
TOP

dbPAF Protein Information

Tag

Content

dbPAF ID

dbPAF-0050685

Uniprot Accession

E9PX29; E9PX29_MOUSE;

Genbank Protein ID

NP_115999.2;

Genbank Nucleotide ID

NM_032610.2;

Protein Name

Protein Sptbn4

Protein Synonyms/Alias

Gene Name

Sptbn4

Gene Synonyms/Alias

Spnb4;

Organism

Mus musculus(Mouse)

NCBI Taxa ID

10090

Functional Description
(View all)

Phosphorylation Sites

dbPAF PTMs: 22 (View all)

Position	Peptides	Source	References ( PMIDs )
28	NPSARWESPDRGWDR	PhosphoSitePlus;curated	22135298; 22817900; 21183079; 22807455
454	NENQRLVSQDNFGYE	curated	22817900
644	RRAELEASRSLWALL	PhosphoSitePlus	22135298
1021	GALQWRLSGLEAALQ	PhosphoSitePlus;curated	22135298; 21183079
1427	KRLLHMESQLQDVDP	PhosphoSitePlus	22135298
1450	SQLKKLQSMESQVEE	PhosphoSitePlus;curated	22135298; 21183079
1453	KKLQSMESQVEEWCR	PhosphoSitePlus	22135298
1579	ERAGVLASLRSPEAE	PHOSIDA	21081558
1582	GVLASLRSPEAEAVR	PHOSIDA;PhosphoSitePlus;curated	21081558; 22135298; 21183079
1748	EKEVVAGSPELGQDF	PHOSIDA;PhosphoSitePlus	21081558; 22135298
1865	APPEPRPSASSMQRT	PhosphoSitePlus	22135298
2075	QSRELGSSVDEVEQL	PhosphoSitePlus;curated	22135298; 21183079
2161	EPLARRASDTLSAEV	PHOSIDA;PhosphoSitePlus;curated	21081558; 22135298; 21183079
2250	RRSERQESVDQPEET	Phospho.ELM 9.0;PHOSIDA;PhosphoSitePlus;curated	16452087; 21081558; 22135298; 25521595
2257	SVDQPEETARRRRPE	curated	25521595
2268	RRPERQESADHEGPH	Phospho.ELM 9.0;PhosphoSitePlus;curated	16452087; 22135298; 25521595
2301	RRIERQESSEQETPT	Phospho.ELM 9.0;PHOSIDA;PhosphoSitePlus;curated	16452087; 21081558; 22135298; 21183079; 25521595; 22807455
2302	RIERQESSEQETPTR	PhosphoSitePlus;curated	22135298; 21183079
2306	QESSEQETPTRGELV	PhosphoSitePlus	22135298
2392	EGGEGGGSRRSRSAP	PhosphoSitePlus	22135298

Sequence
(Fasta)

MAQVPGEVDN MEGPAVSNNN NPSARWESPD RGWDREPPAA ANAAASLFEC SRIKALADER 60
EAVQKKTFTK WVNSHLARVG CHIGDLYADL RDGFVLTRLL EVLSGEQLPR PTRGRMRIHS 120
LENVDKALQF LKEQRVHLEN VGSHDIVDGN HRLTLGLVWT IILRFQIQVI KIETEDNRET 180
RSAKDALLLW CQMKTAGYPE VNIQNFTTSW RDGLAFNALI HRHRPDLVDL SKLTKSNANY 240
NLQRAFRTAE QHLGLARLLD PEDVNMEAPD EKSIITYVVS FYHYFSKMKA LAVEGKRIGK 300
VLDQVLEVDK IIERYEELAA ELLAWIHRTV DLISNQKFAN SLSGVQQQLQ AFTAYCTLEK 360
PVKFQEKGNL EVLLFSIQSK LRAHNRRLFV PREGCGIWDI DKAWGELEKA EHEREAALRA 420
ELIRQEKLEL LAQRFDHKVA MRESWLNENQ RLVSQDNFGY ELPAVEAAMK KHEAIEADIA 480
AYEERVQGVA ELAQALAAEG YYDARRVAAQ RDSVLRQWAL LTGLVGARRT RLEQNLALQK 540
VFQEMVYMVD WMEEMQTQLL SRECGQHLVE ADDLLQKHGL LEGDIAAQSE RVEALNAAAL 600
RFSQLQGYQP CDPQVICNRV NHVHGCLSEL QEQAARRRAE LEASRSLWAL LQELEEAESW 660
ARDKERLLEA TSGSGGAAGT AGGAHDLSST ARLLAQHKIL QGELGGRRAL LQQALRRGEE 720
LAAAGGSVGP GAEPLHLAGL AERAASARRR WQRLEEAAAR RERRLQEARA LHQFGADLDG 780
LLDWLRDAYR LAAAGDFGHD EASSRRLARQ HRALTGEVEA HRGPVGGLRR QLATLGGASG 840
AGPLVVALQV RVVEAEQLFA EVTEVAALRR QWLRDALAVY RMFGEVHACE LWIGEKEQWL 900
LAMRVPDSLD DVEVVQHRFE SLDQEMNSLM GRVLDVNQTV QELVEGGHPS SDEVRSCQDH 960
LNSRWNRIVE LVEQRKEEMS AVLLVENHVL EVAEVRAQVR EKRRAVESAP RAGGALQWRL 1020
SGLEAALQAL EPRQAALLEE AALLAERFPA QATRLHQGAE ELGAEWGALA GAAQACGEAV 1080
AAAGRLQRFL RDLDTFLDWL VRAQEAAGAV EGPLPRSLEE ADGLLARHAA LKEEVDQREE 1140
DYARIVAASE ALLASEGAEL GPGLALDEWL PHLEVGWHKL LGLWEERREA LVQAHVYQLF 1200
LRDLCQALAV LRNQEVALSG AELPCTVESV EEAMKRHRDF LTTMELNQQK MQVAVQAAES 1260
LLRQGNAYGE QAQEAVARLL EKSQENQLRA QQWMQKLLDQ LVLQHFLRDC HELDGWIHEK 1320
MLMARDGTRE DSHKLHKRWL RHQAFMAELA QNKEWLEKIE REGQQLMQEK PELAASVRKK 1380
LGEIRQCWAE LESTTQAKAR QLFEASKADQ LVQSFAELDK RLLHMESQLQ DVDPGGDLAT 1440
VNSQLKKLQS MESQVEEWCR EVGELQAQTA ALPLEQASKE LVGERQSAVG ERLVRLLEPL 1500
QERRRLLLAS KELHQVAHDL DDELAWVQER LPLAMQTERG TGLQAVQQHI KKNQGLRREI 1560
QAHGPRLEEV LERAGVLASL RSPEAEAVRR GQEQLQSAWT GLREAAERRQ QTLDAAFQVE 1620
QYYFDVAEVE AWLGEQELLM MSEDKGKDEQ STLQLLKKHL QLEQGVENYE ESIAQLSRQC 1680
RALLEMGHPD SEQISRRQSQ VDRLYVALKE LGEERRVSLE QQYWLYQLSR QVDELEHWIA 1740
EKEVVAGSPE LGQDFEHVSV LQEKFSEFAS ETGTAGRERL AAVNQMVDEL IECGHTAAAT 1800
MAEWKDGLNE AWAELLELMG TRAQLLAASR ELHKFFSDAR ELQGQIEEKR RRLPRLTAPP 1860
EPRPSASSMQ RTLRAFEHDL QLLVSQVRQL QEGAAQLRTV YAGEHAEAIA SREQEVLQGW 1920
KELLAACEDA RLHVSSTADA LRFHSQARDL LSWMDGIAGQ IGAADKPRDV SSVEVLMNYH 1980
QGLKTELEAR VPELATCQEL GRSLLLNKSA MADEIQAQLD KLGSRKEEVS EKWDRHWEWL 2040
QQMLEVHQFA QEAVVADAWL TAQEPLLQSR ELGSSVDEVE QLIRRHEAFR KAAAAWEERF 2100
SSLRRLTTIE KLKAEQSKQP PTPLLGRKFF GDPTELAAKA APLLRPGGYD RGLEPLARRA 2160
SDTLSAEVRT RVGYVRQELK PERLQPRIDR LPETSGKVEP AAPTAAALDT TDTPGTPAAT 2220
ELVRPRSERQ ELADRAEELP RRRRSERQES VDQPEETARR RRPERQESAD HEGPHSLTLG 2280
RYEQMERRRE RRERRIERQE SSEQETPTRG ELVKGKATLA DIVEQLQEKE AGPGIPAGVP 2340
SLPQPRELPP GRLPNGLEPP ERTPRPDRPR ARDRPKPRRR PRPREGGEGG GSRRSRSAPA 2400
QGGSAPAPPP PPTHTVQHEG FLLRKRELDA NRKSSNRSWV SLYCVLSKGE LGFYKDSKGP 2460
ASGGTHGGEP LLSLHKATSE VASDYKKKKH VFKLQTQDGS EFLLQAKDEE EMNGWLEAVA 2520
NSVAEHAEIA RWGQTLPTTS STDEGNPKRE GGERRASGRR K 2562

Fasta Sequence

>E9PX29|Sptbn4|Mus musculus(Mouse)
MAQVPGEVDNMEGPAVSNNNNPSARWESPDRGWDREPPAAANAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYADLRDGFVLTRLLEVLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDLSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEKSIITYVVSFYHYFSKMKALAVEGKRIGKVLDQVLEVDKIIERYEELAAELLAWIHRTVDLISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFSIQSKLRAHNRRLFVPREGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRLVSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDARRVAAQRDSVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQTQLLSRECGQHLVEADDLLQKHGLLEGDIAAQSERVEALNAAALRFSQLQGYQPCDPQVICNRVNHVHGCLSELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEATSGSGGAAGTAGGAHDLSSTARLLAQHKILQGELGGRRALLQQALRRGEELAAAGGSVGPGAEPLHLAGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEASSRRLARQHRALTGEVEAHRGPVGGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEVTEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLAMRVPDSLDDVEVVQHRFESLDQEMNSLMGRVLDVNQTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAVLLVENHVLEVAEVRAQVREKRRAVESAPRAGGALQWRLSGLEAALQALEPRQAALLEEAALLAERFPAQATRLHQGAEELGAEWGALAGAAQACGEAVAAAGRLQRFLRDLDTFLDWLVRAQEAAGAVEGPLPRSLEEADGLLARHAALKEEVDQREEDYARIVAASEALLASEGAELGPGLALDEWLPHLEVGWHKLLGLWEERREALVQAHVYQLFLRDLCQALAVLRNQEVALSGAELPCTVESVEEAMKRHRDFLTTMELNQQKMQVAVQAAESLLRQGNAYGEQAQEAVARLLEKSQENQLRAQQWMQKLLDQLVLQHFLRDCHELDGWIHEKMLMARDGTREDSHKLHKRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWAELESTTQAKARQLFEASKADQLVQSFAELDKRLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWCREVGELQAQTAALPLEQASKELVGERQSAVGERLVRLLEPLQERRRLLLASKELHQVAHDLDDELAWVQERLPLAMQTERGTGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAGVLASLRSPEAEAVRRGQEQLQSAWTGLREAAERRQQTLDAAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQISRRQSQVDRLYVALKELGEERRVSLEQQYWLYQLSRQVDELEHWIAEKEVVAGSPELGQDFEHVSVLQEKFSEFASETGTAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAELLELMGTRAQLLAASRELHKFFSDARELQGQIEEKRRRLPRLTAPPEPRPSASSMQRTLRAFEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLAACEDARLHVSSTADALRFHSQARDLLSWMDGIAGQIGAADKPRDVSSVEVLMNYHQGLKTELEARVPELATCQELGRSLLLNKSAMADEIQAQLDKLGSRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVVADAWLTAQEPLLQSRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRRLTTIEKLKAEQSKQPPTPLLGRKFFGDPTELAAKAAPLLRPGGYDRGLEPLARRASDTLSAEVRTRVGYVRQELKPERLQPRIDRLPETSGKVEPAAPTAAALDTTDTPGTPAATELVRPRSERQELADRAEELPRRRRSERQESVDQPEETARRRRPERQESADHEGPHSLTLGRYEQMERRRERRERRIERQESSEQETPTRGELVKGKATLADIVEQLQEKEAGPGIPAGVPSLPQPRELPPGRLPNGLEPPERTPRPDRPRARDRPKPRRRPRPREGGEGGGSRRSRSAPAQGGSAPAPPPPPTHTVQHEGFLLRKRELDANRKSSNRSWVSLYCVLSKGELGFYKDSKGPASGGTHGGEPLLSLHKATSEVASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMNGWLEAVANSVAEHAEIARWGQTLPTTSSTDEGNPKREGGERRASGRRK

Keyword

KW-0009--Actin-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR001589--Actinin_actin-bd_CS
IPR001715--CH-domain
IPR011993--PH/PTB_dom
IPR001605--PH_dom-spectrin-type
IPR001849--PH_domain
IPR018159--Spectrin/alpha-actinin
IPR016343--Spectrin_bsu
IPR002017--Spectrin_repeat

PROSITE

PS00019--ACTININ_1
PS00020--ACTININ_2
PS50021--CH
PS50003--PH_DOMAIN

Pfam

PF00307--CH
PF00435--Spectrin

Gene Ontology

GO:0030424--C:axon
GO:0043203--C:axon hillock
GO:0043194--C:axon initial segment
GO:0070852--C:cell body fiber
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0016020--C:membrane
GO:0043025--C:neuronal cell body
GO:0016363--C:nuclear matrix
GO:0033270--C:paranode region of axon
GO:0016605--C:PML body
GO:0008091--C:spectrin
GO:0003779--F:actin binding
GO:0030506--F:ankyrin binding
GO:0019902--F:phosphatase binding
GO:0005543--F:phospholipid binding
GO:0030507--F:spectrin binding
GO:0005200--F:structural constituent of cytoskeleton
GO:0030534--P:adult behavior
GO:0007628--P:adult walking behavior
GO:0007409--P:axonogenesis
GO:0061337--P:cardiac conduction
GO:0034613--P:cellular protein localization
GO:0021952--P:central nervous system projection neuron axonogenesis
GO:0045162--P:clustering of voltage-gated sodium channels
GO:0009566--P:fertilization
GO:0010459--P:negative regulation of heart rate
GO:0040018--P:positive regulation of multicellular organism growth
GO:0033135--P:regulation of peptidyl-serine phosphorylation
GO:0002028--P:regulation of sodium ion transport
GO:0022414--P:reproductive process
GO:0007605--P:sensory perception of sound
GO:0019226--P:transmission of nerve impulse