| Tag |
Content |
| dbPAF ID |
dbPAF-0050682 |
| Uniprot Accession |
E9PWZ6; E9PWZ6_MOUSE;
|
| Genbank Protein ID |
NP_001135795.1;
|
| Genbank Nucleotide ID |
NM_001142323.1;
|
| Protein Name |
Unconventional myosin-IXb |
| Protein Synonyms/Alias |
|
| Gene Name |
Myo9b |
| Gene Synonyms/Alias |
|
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 6 |
Sequence
(Fasta) | MSAHEAGSSG RRQQATYHLH IYPQLSSAGS QTSCRVTATK DSTTSDVIQD VVASLHLDGS 60
KHYVLVEVKE SGGEEWVLDA SDSPVHRVLL WPRRAQDEHP QEDGYYFLLQ ERNADGSIQY 120
LPIQLLAQPT AACRLVERGL LPRPQADFDD LCNLPELTEA NLLQNLKLRF MQQKIYTYAG 180
SILVAINPFK FLPIYNPKYV KMYENQQLGK LEPHVFALAD VAYYAMLRKH VNQCIVISGE 240
SGSGKTQSTN FLIHCLTALS QKGYASGVER TILGAGPVLE AFGNAKTAHN NNSSRFGKFI 300
QVNYLENGIV RGAVVEKYLL EKSRLVSQEK DERNYHVFYY LLLGVSEEER LEFQLKQPQD 360
YFYLNQHNLN IEDGEDLKHD FERLQQAMEM VGFLPATKKQ IFSVLSAILY LGNVTYKKRA 420
TGRDEGLEVG PPEVLDTLSQ LLKVKRETLV EVLTKRKTVT VNDKLILPYS LSEAITARDS 480
MAKSLYSALF DWIVLRINHA LLNKKDMEEA VSCLSIGVLD IFGFEDFERN SFEQFCINYA 540
NEQLQYYFTQ HIFKLEQEEY QGEGISWHNI DYTDNVGCIH LISKKPTGLF YLLDEESNFP 600
HATSHTLLAK FKQQHEDNKY FLGTPVLEPA FIIQHFAGRV KYQIKDFREK NMDYMRPDIV 660
ALLRGSDSSY VRQLIGMDPV AVFRWAVLRA AIRAMAVLRE AGRLRAERAE KAAGISSPAT 720
RSHMEELPRG ASTPSEKLYR DLHNQIIKSL KGLPWQGEDP RRLLQSLSLF QKPRTSFLKS 780
KGIKQKQIIP KNLLDSKSLR LIISMTLHDR TTKSLLHLHK KKKPPSISAQ FQTSLNKLLE 840
ALGKAEPFFI RCIRSNAEKK ELCFDDELVL QQLRYTGMLE TVRIRRSGYS AKYTFQDFTE 900
QFQVLLPKDV QPCREAIAAL LEKLQVDRQN YQIGKTKVFL KETERQTLQE KLHGEVLRRI 960
LQLQSWFRMV LERKHFVQMK HAALTIQACW RSYRVRRALE RTQAAVYLQA AWRGYLQRQA 1020
YHHQRHSIIR LQSLCRGHLQ RRSFSQMVSE KQKAEQAREA AGGKLSEGEP GPVAAGEQLS 1080
EHPVEDPESL GVEAETWMNK SPDGMSPKKE TPSPEMETAA QKTVPAESHE KVSSSREKRE 1140
SRRQRGLEHV ERQNKHIQSC REESSTHREP SRRASLEIGE SFPEGTKGPR EDGLEAWTET 1200
TAPSSSKQAQ VVGDPPGSPS PVQRPTTLAL DSRVSPMLPS SSLEVSPVLP SSSLESPKDK 1260
DKDESSTKAQ DKPESPSGST QIQRYQHPDT ERLATAVEIW RGKKLASAVL SQSLDLSEKH 1320
RATGAALTPT EERRISFSTS DVSKLSPVKV QTSAEIDGDF SSKKPSIHKK KSGDPSAGPD 1380
AGLSPGSQGD SKSAFKRLFL HKAKDKKPSL EGVEETESNG GQAAQETPAR KTLDVPSSQQ 1440
HRHTTGEKPL KGKKNRNRKV GQITVSEKWR ESVFRKITNA NELKFLDEFL LNKVNDLRSQ 1500
KTPIESLFIE ATERFRSNIK TMYSVPNGKI HVGYKDLMEN YQIVVSNLAA ERGEKDTNLV 1560
LNVFQSLLDE FTRSYNKTDF ERAKQSKAQK KKRKQERAVQ EHNGHVFASY QVNIPQSCEQ 1620
CLSYIWLMDK ALLCSVCKMT CHKKCVHKIQ SYCSYTGRRK SELGAEPGHF GVCVDSLTSD 1680
KASVPIVLEK LLEHVEMHGL YTEGLYRKSG AANRTRELRQ ALQTDPAAVK LEDFPIHAIT 1740
GVLKQWLREL PEPLMTFAQY GDFLRAVELP EKQEQLSAIY AVLDHLPEAN HTSLERLIFH 1800
LVKVALLEDV NRMSPGALAI IFAPCLLRCP DNSDPLTSMK DVLKITTCVE MLIKEQMRKY 1860
KMKMEEINHL EAAESIAFRR LSLLRQNAIK SPRTPVVQDL ELGALPEEAA GGDEDREKEI 1920
LMERIQSIKE EKEDITYRLP ELDPRGSDEE NLDSETSAST ESLLEERGVR GAVEE
1976Fasta Sequence
>E9PWZ6|Myo9b|Mus musculus(Mouse)
MSAHEAGSSGRRQQATYHLHIYPQLSSAGSQTSCRVTATKDSTTSDVIQDVVASLHLDGSKHYVLVEVKESGGEEWVLDASDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGSIQYLPIQLLAQPTAACRLVERGLLPRPQADFDDLCNLPELTEANLLQNLKLRFMQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYAMLRKHVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYLENGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERLEFQLKQPQDYFYLNQHNLNIEDGEDLKHDFERLQQAMEMVGFLPATKKQIFSVLSAILYLGNVTYKKRATGRDEGLEVGPPEVLDTLSQLLKVKRETLVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDMEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFTQHIFKLEQEEYQGEGISWHNIDYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSHTLLAKFKQQHEDNKYFLGTPVLEPAFIIQHFAGRVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRQLIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGISSPATRSHMEELPRGASTPSEKLYRDLHNQIIKSLKGLPWQGEDPRRLLQSLSLFQKPRTSFLKSKGIKQKQIIPKNLLDSKSLRLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLLPKDVQPCREAIAALLEKLQVDRQNYQIGKTKVFLKETERQTLQEKLHGEVLRRILQLQSWFRMVLERKHFVQMKHAALTIQACWRSYRVRRALERTQAAVYLQAAWRGYLQRQAYHHQRHSIIRLQSLCRGHLQRRSFSQMVSEKQKAEQAREAAGGKLSEGEPGPVAAGEQLSEHPVEDPESLGVEAETWMNKSPDGMSPKKETPSPEMETAAQKTVPAESHEKVSSSREKRESRRQRGLEHVERQNKHIQSCREESSTHREPSRRASLEIGESFPEGTKGPREDGLEAWTETTAPSSSKQAQVVGDPPGSPSPVQRPTTLALDSRVSPMLPSSSLEVSPVLPSSSLESPKDKDKDESSTKAQDKPESPSGSTQIQRYQHPDTERLATAVEIWRGKKLASAVLSQSLDLSEKHRATGAALTPTEERRISFSTSDVSKLSPVKVQTSAEIDGDFSSKKPSIHKKKSGDPSAGPDAGLSPGSQGDSKSAFKRLFLHKAKDKKPSLEGVEETESNGGQAAQETPARKTLDVPSSQQHRHTTGEKPLKGKKNRNRKVGQITVSEKWRESVFRKITNANELKFLDEFLLNKVNDLRSQKTPIESLFIEATERFRSNIKTMYSVPNGKIHVGYKDLMENYQIVVSNLAAERGEKDTNLVLNVFQSLLDEFTRSYNKTDFERAKQSKAQKKKRKQERAVQEHNGHVFASYQVNIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSYCSYTGRRKSELGAEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLEDFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLSAIYAVLDHLPEANHTSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKEQMRKYKMKMEEINHLEAAESIAFRRLSLLRQNAIKSPRTPVVQDLELGALPEEAAGGDEDREKEILMERIQSIKEEKEDITYRLPELDPRGSDEENLDSETSASTESLLEERGVRGAVEE
|
| Keyword |
KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0505--Motor protein
KW-0518--Myosin
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
|
| Interpro |
IPR000048--IQ_motif_EF-hand-BS
IPR028557--MYO9B
IPR001609--Myosin_head_motor_dom
IPR027417--P-loop_NTPase
IPR002219--PE/DAG-bd
IPR000159--RA_dom
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR029071--Ubiquitin-rel_dom
|
| PROSITE |
PS50096--IQ
PS51456--MYOSIN_MOTOR
PS50200--RA
PS50238--RHOGAP
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2
|
| Pfam |
PF00612--IQ
PF00063--Myosin_head
PF00788--RA
PF00620--RhoGAP
|
| Gene Ontology |
GO:0005938--C:cell cortex
GO:0005737--C:cytoplasm
GO:0031941--C:filamentous actin
GO:0032433--C:filopodium tip
GO:0030027--C:lamellipodium
GO:0016020--C:membrane
GO:0016459--C:myosin complex
GO:0048471--C:perinuclear region of cytoplasm
GO:0001726--C:ruffle
GO:0003779--F:actin binding
GO:0051015--F:actin filament binding
GO:0030898--F:actin-dependent ATPase activity
GO:0043531--F:ADP binding
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0005516--F:calmodulin binding
GO:0005096--F:GTPase activator activity
GO:0046872--F:metal ion binding
GO:0000146--F:microfilament motor activity
GO:0003774--F:motor activity
GO:0033275--P:actin-myosin filament sliding
GO:0030010--P:establishment of cell polarity
GO:0072673--P:lamellipodium morphogenesis
GO:0048246--P:macrophage chemotaxis
GO:0002548--P:monocyte chemotaxis
GO:0043547--P:positive regulation of GTPase activity
GO:0007266--P:Rho protein signal transduction
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