dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050678
Uniprot Accession E9PWT1; E9PWT1_MOUSE;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Transformation/transcription domain-associated protein
Protein Synonyms/Alias
Gene Name Trrap
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 16
PositionPeptidesSourceReferences ( PMIDs )
6--MAFVATQGATVVDPhosphoSitePlus22135298
10FVATQGATVVDQTTLPhosphoSitePlus;curated22135298; 21183079
16ATVVDQTTLMKKYLQPhosphoSitePlus;curated22135298; 21183079
21QTTLMKKYLQFVAALPhosphoSitePlus22135298
29LQFVAALTDVNTPDEPhosphoSitePlus22135298
33AALTDVNTPDETKLKPhosphoSitePlus22135298
37DVNTPDETKLKMMQEPhosphoSitePlus22135298
46LKMMQEVSENFENVTPhosphoSitePlus22135298
55NFENVTSSPQYSTFLPhosphoSitePlus22135298
58NVTSSPQYSTFLEHIPhosphoSitePlus22135298
59VTSSPQYSTFLEHIIPhosphoSitePlus22135298
60TSSPQYSTFLEHIIPPhosphoSitePlus22135298
886TLRNPADSISHVAYRPhosphoSitePlus;curated22135298; 21183079
892DSISHVAYRVLGKFGPhosphoSitePlus;curated22135298; 21183079
1630AVRPGSPSTSNMRLDPhosphoSitePlus22135298
1632RPGSPSTSNMRLDLQPhosphoSitePlus22135298
Sequence
(Fasta)
MAFVATQGAT VVDQTTLMKK YLQFVAALTD VNTPDETKLK MMQEVSENFE NVTSSPQYST 60
FLEHIIPRFL TFLQDGEVQF LQEKPAQQLR KLVLEILHRI PTNEHLRPHT KNVLSVMFRF 120
LETENEENVL ICLRIIIELH KQFRPPITQE IHHFLDFVKQ IYKELPKVVN RYFENPQGIP 180
ENTVPPPEMV GMITTVAVKV NPEREDSETR THSIIPRGSL SLKVLAELPI IVVLMYQLYK 240
LNIHNVVAEF VPLIMNTIAI QVSTQARQHK LYNKELYADF IAAQIKTLSF LAYIIRIYQE 300
LVTKYSQQMV KGMLQLLSNC PAETAHLRKE LLIAAKHILT TELRNQFIPC MDKLFDESIL 360
IGSGYTARET LRPLAYSTLA DLVHHVRQHL PLSDLSLAVQ LFAKNIDDES LPSSIQTMSC 420
KLLLNLVDCI RSKSEQESGN GRDVLMRMLE VFVLKFHTIA RYQLSAIFKK CKPQSELGAA 480
EAALPGVPTA PAAPGPAPSP APVPAPAPPP PPPPAPATPV TPAPVPPFEK QGEKDKEDKQ 540
TFQVTDCRSL VKTLVCGVKT ITWGITSCKA PGAQFIPNKQ LQPKETQIYI KLVKYAMQAL 600
DIYQVQIAGN GQTYIRVANC QTVRMKEEKE VLEHFAGVFT MMNPLTFKEI FQTTVPYMVE 660
RISKNYALQI VANSFLANPT TSALFATILV EYLLERLPEM GSNVELSNLY LKLFKLVFGS 720
VSLFAAENEQ MLKPHLHKIV NSSMELAQTA KEPYNYFLLL RALFRSIGGG SHDLLYQEFL 780
PLLPNLLQGL NMLQSGLHKQ HMKDLFVELC LTVPVRLSSL LPYLPMLMDP LVSALNGSQT 840
LVSQGLRTLE LCVDNLQPDF LYDHIQPVRA ELMQALWRTL RNPADSISHV AYRVLGKFGG 900
SNRKMLKESQ KLHYVVTEVQ GPSITVEFSD CKASLQLPME KAIETALDCL KSANTEPYYR 960
RQAWEVIRCF LVAMMSLEDN KHALYQLLAH PNFTEKTIPN VIISHRYKAQ DTPARKTFEQ 1020
ALTGAFMSAV IKDLRPSALP FVASLIRHYT MVAVAQQCGP FLLPCYQVGS QPSTAMFHSE 1080
ENGSKGMDPL VLIDAIAICM AYEEKELCKI GEVALAVIFD VASIILGSKE RACQLPLFSY 1140
IVERLCACCY EQAWYAKLGG VVSIKFLMER LPLTWVLQNQ QTFLKALLFV MMDLTGEVSN 1200
GAVAMAKTTL EQLLMRCATP LKDEERAEEI VLAQEKSFHH VTHDLVREVT SPNSTVRKQA 1260
MHSLQVLAQV TGKSVTVIME PHKEVLQDMV PPKKHLLRHQ PANAQIGLME GNTFCTTLQP 1320
RLFTMDLNVV EHKVFYTELL NLCEAEDSAL TKLPCYKSLP SLVPLRIAAL NALAACNYLP 1380
QSREKIIAAL FKALNSTNSE LQEAGEACMR KFLEGATIEV DQIHTHMRPL LMMLGDYRSL 1440
TLNVVNRLTS VTRLFPNSFN DKFCDQMMQH LRKWMEVVVI THKGGQRSDG NESLSECGRC 1500
SLSPFCQFEE MKICSAIINL FHLIPAAPQT LVKPLLEVVM KTERAMLIEA GSPFREPLIK 1560
FLTRHPSQTV ELFMMEATLN DPQWSRMFMS FLKHKDARPL RDVLAANPNR FITLLLPGGA 1620
QTAVRPGSPS TSNMRLDLQF QAIKIISIIV KNDDAWLASQ HSLVSQLRRV WVSETFQERH 1680
RKENMAATNW KEPKLLAFCL LNYCKRNYGD IELLFQLLRA FTGRFLCNMT FLKEYMEEEI 1740
PKNYSIAQKR ALFFRFVEFN DPNFGDELKA KVLQHILNPA FLYSFEKGEG EQLLGPPNPE 1800
GDNPESITSV FITKVLDPEK QADMLDSLRI YLLQYATLLV EHAPHHIHDN NKNRNSKLRR 1860
LMTFAWPCLL SKACVDPACK YSGHLLLAHI IAKFAIHKKI VLQVFHSLLK AHAMEARAIV 1920
RQAMAILTPA VPARMEDGHQ MLTHWTRKII VEEGHTVPQL VHILHLIVQH FKVYYPVRHH 1980
LVQHMVSAMQ RLGFTPSVTI EQRRLAVDLS EVVIKWELQR IKDQQPDSDM DPNSSGEGVN 2040
SVSIKRGLSV DSAQEVKRFR AATGAISAVF GRSQSLPGAD SLLAKPIDKQ HTDTVVNFLI 2100
RVACQVNDNT NTAGSPGEVL SRRCVNLLKT ALRPDMWCKS ELKLQWFDKL LMTVEQPNQV 2160
NYGNICTGLE VLNFLLTVLQ SPAILSSFKP LQRGIAACMT CGNTKVLRAV HSLLSRLMSI 2220
FPTEPSTSSV ASKYEELECL YAAVGKVIYE GLTNYEKATS ANPSQLFGTL MILKSACCNN 2280
PSYIDRLISV FMRSLQKMVR EHLNPQTASG STEATAAGTS ELVMLSLDLV KTRLAVMSME 2340
MRKNFIQTIL TSLIEKSPDA KILRAVVKIV EEWVKNNSPM AANQTPTLRE KSILLVKMMT 2400
YIEKRFPEDL ELNAQFLDLV NYVYRDEALS GSELTAKLEP AFLSGLRCAQ PLIRAKFFEV 2460
FDNSMKRRVY ERLLYVTCSQ NWEAMGSHFW IKQCIELLLA VCEKSTAIGT SCQGAMLPSI 2520
TNVINLADSH DRAAFAMVTH VKQEPREREN SESKEEDVEI DIELAPGDQT STPKTKELSE 2580
KDIGNQLHML TNRHDKFLDT LREVKTGALL SAFVQLCHIS TTLAEKTWVQ LFPRLWKILS 2640
DRQQHALAGE ISPFLCSGSH QVQRDCQPSA LNCFVEAMSQ CVPPIPMRPC VLKYLGKTHN 2700
LWFRSTLMLE HQAFEKGLSL PIKPKQTTEF YEQESITPPQ QEILDSLAEL YSLLQEEDMW 2760
AGLWQKRCKF SETATAIAYE QHGFFEQAQE SYEKAMDKAK KEHERSNASP AIFPEYQLWE 2820
DHWIRCSKEL NQWEALTEFG QSKGHINPYL VLECAWRVSN WTAMKEALVQ VEVSCPKEMA 2880
WKVNMYRGYL AICHPEEQQL SFIERLVEMA SSLAIREWRR LPHVVSHVHT PLLQAAQQII 2940
ELQEAAQINA GLQPTNLGRN NSLHDMKTVV KTWRNRLPIV SDDLSHWSSV FMWRQHHYQG 3000
KPTWSGMHSS SIVTAYENSS HHDPSSNNAM LGVHASASAI IQYGKIARKQ GLVNVALDIL 3060
SRIHTIPTVP IVDCFQKIRQ QVKCYLQLAG VMGKNECMQG LEVIESTNLK YFTKEMTAEF 3120
YALKGMFLAQ INKSEEANKA FSAAVQMHDV LVKAWAMWGD YLESIFVKER QLHLGVSAIT 3180
CYLHACRHQN ESKSRKYLAK VLWLLSFDDD KNTLADAVDK YCIGVPPIQW LAWIPQLLTC 3240
LVGSEGKLLL NLISQVGRVY PQAVYFPIRT LYLTLKIEQR ERYKSDPGPI RATAPMWRCS 3300
RIMHMQRELH PTLLSSLEGI VDQMVWFREN WHEEVLRQLQ QGLAKCYSVA FEKSGAVSDA 3360
KITPHTLNFV KKLVSTFGVG LENVSNVSTM FSSAASESLA RRAQATAQDP VFQKLKGQFT 3420
TDFDFSVPGS MKLHNLISKL KKWIKILEAK TKQLPKFFLI EEKCRFLSNF SAQTAEVEIP 3480
GEFLMPKPTH YYIKIARFMP RVEIVQKHNT AARRLHIRGH NGKIYPYLVM NDACLTESRR 3540
EERVLQLLRL LNPCLEKRKE TTKRHLFFTV PRVVAVSPQM RLVEDNPSSL SLVEIYKQRC 3600
AKKGIEHDNP ISRYYDRLAT VQARGTQASH QVLRDILKEV QSNMVPRSML KEWALHTFPN 3660
ATDYWTFRKM FTIQLALIGF AEFVLHLNRL NPEMLQIAQD TGKLNVAYFR FDINDATGDL 3720
DANRPVPFRL TPNISEFLTT IGVSGPLTAS MIAVARCFAQ PNFKVDGVLK TVLRDEIIAW 3780
HKKTQEDTSS PLSAAGQPEN MDSQQLVSLV QKAVTAIMTR LHNLAQFDGG ESKVNTLVAA 3840
ANSLDNLCRM DPAWHPWL 3859
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR003152--FATC_dom
IPR011009--Kinase-like_dom
IPR000403--PI3/4_kinase_cat_dom
IPR003151--PIK-rel_kinase_FAT
IPR014009--PIK_FAT
IPR011990--TPR-like_helical_dom

PROSITE

PS51189--FAT
PS51190--FATC
PS50290--PI3_4_KINASE_3

Pfam

PF02259--FAT
PF00454--PI3_PI4_kinase

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0000123--C:histone acetyltransferase complex
GO:0035267--C:NuA4 histone acetyltransferase complex
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0030914--C:STAGA complex
GO:0000812--C:Swr1 complex
GO:0005667--C:transcription factor complex
GO:0033276--C:transcription factor TFTC complex
GO:0016301--F:kinase activity
GO:0016773--F:phosphotransferase activity, alcohol group as acceptor
GO:0003713--F:transcription coactivator activity
GO:0003712--F:transcription cofactor activity
GO:0006281--P:DNA repair
GO:0016578--P:histone deubiquitination
GO:0043968--P:histone H2A acetylation
GO:0043967--P:histone H4 acetylation
GO:0007093--P:mitotic cell cycle checkpoint
GO:0016310--P:phosphorylation
GO:0006355--P:regulation of transcription, DNA-templated