dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050672
Uniprot Accession E9PWP6; E9PWP6_MOUSE;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Regulating synaptic membrane exocytosis protein 1
Protein Synonyms/Alias
Gene Name Rims1
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
379EYQTRYRSDPNLARYPhosphoSitePlus22135298
413ARHERRHSDVALPHTPhosphoSitePlus;curated22135298; 21183079; 22807455
438TAGKRAQTTARVSPPPhosphoSitePlus;curated22135298; 25521595
439AGKRAQTTARVSPPEPhosphoSitePlus;curated22135298; 25521595
443AQTTARVSPPESPRAPhosphoSitePlus;curated22135298; 21183079; 22807455; 25521595
447ARVSPPESPRARAPAPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 21183079; 25521595
514ESMLRNDSLSSDQSEPhosphoSitePlus;curated22135298; 21183079
516MLRNDSLSSDQSESVPhosphoSitePlus22135298
517LRNDSLSSDQSESVRPhosphoSitePlus22135298
526QSESVRPSPPKPHRPPhosphoSitePlus;curated22135298; 21183079; 22807455
Sequence
(Fasta)		MSSAVGPRGP RPPTVPPPMQ ELPDLSHLTE EERNIIMAVM DRQKEEEEKE EAMLKCVVRD 60
MAKPAACKTP RNAESQPHQP PLNIFRCVCV PRKPSSEEGG PDRNWRLHQQ FESYKEQVRK 120
IGEEARRYQG EHKDDAPTCG ICHKTKFADG CGHLCSYCRT KFCARCGGRV SLRSNNEDKV 180
VMWVCNLCRK QQEILTKSGA WFFGSGPQQP SQDGTLSDTA TGAGSEVPRE KKARLQERSR 240
SQTPLSTAAV SSQDTASHGA PLDRNKGAEP SQQALGPEQK QASRSRSEPP RERKKAPGLS 300
EQNGKGGQKS ERKRVPKSVV QPGEGTADER ERKERRETRR LEKGRSQDYP DRLEKREDGR 360
VAEDEKQRKE EEYQTRYRSD PNLARYPVKA PLEEQQMRMH ARVSRARHER RHSDVALPHT 420
EAAAAVSAET TAGKRAQTTA RVSPPESPRA RAPAAQPPAE HGPPPPRPAP GPAEPPEPRV 480
PEPLRKQGRL DPGSAVLLRK AKREKAESML RNDSLSSDQS ESVRPSPPKP HRPKRGGKRR 540
QMSVSSSEEE GVSTPEYTSC EDVELESESV SEKGDLDYWL DPATWHSRET SPISSHPVTW 600
QPSKEGDRLI GRVILNKRTT MPKESGALLG LKVVGGKMTD LGRLGAFITK VKKGSLADVV 660
GHLRAGDEVL EWNGKPLPGA TNEEVYNIIL ESKSEPQVEI IVSRPIGDIP RIPESSHPPL 720
ESSSSSFESQ KMERPSISVI SPTSPGALKD APQVLPGQLS VKLWYDKVGH QLIVNVLQAT 780
DLPPRVDGRP RNPYVKMYFL PDR 804
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000008--C2_dom
IPR001478--PDZ
IPR010911--Rab_BD
IPR030630--RIM1
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50106--PDZ
PS50916--RABBD
PS50178--ZF_FYVE
Pfam

PF02318--FYVE_2
PF00595--PDZ
Gene Ontology

GO:0005622--C:intracellular
GO:0016020--C:membrane
GO:0014069--C:postsynaptic density
GO:0048786--C:presynaptic active zone
GO:0045202--C:synapse
GO:0044325--F:ion channel binding
GO:0046872--F:metal ion binding
GO:0044822--F:poly(A) RNA binding
GO:0048791--P:calcium ion-dependent exocytosis of neurotransmitter
GO:0006887--P:exocytosis
GO:0006886--P:intracellular protein transport
GO:0007269--P:neurotransmitter secretion
GO:1903861--P:positive regulation of dendrite extension
GO:0006461--P:protein complex assembly
GO:0048169--P:regulation of long-term neuronal synaptic plasticity
GO:0042391--P:regulation of membrane potential