dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050671
Uniprot Accession E9PWN3; E9PWN3_MOUSE;
Genbank Protein ID XP_006497242.1; XP_006497243.1;
Genbank Nucleotide ID XM_006497179.2; XM_006497180.2;
Protein Name Isoleucine--tRNA ligase, mitochondrial
Protein Synonyms/Alias
Gene Name Iars2
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
543HHKTKDEYLINRRMLcurated20469934
556MLSPALLTYALR---curated20469934
Sequence
(Fasta)		MHWGLCPRGP GAAAVAAAGS FWGPARLPSR LGCLGMTRRL VVRSVAGADS PQSSSKGGRY 60
RDTVLLPQTS FPMKLLGRQQ SDMELEIQQK CGFSELYSWQ RERKVKTEFC LHDGPPYANG 120
DPHVGHALNK ILKDIANRFH MMRGSKVHFV PGWDCHGLPI ETKVLSELGV DAQSLSAMEI 180
REKARSFAQA AIEKQKSAFV RWGVMADWNN CYYTFDPKYE AKQLRVFYQM YEKGLVYRSY 240
KPVYWSPSSR TALAEAELEY NPEHVSRSIY VRFPLLRPPP KLESLTDASS PVSVLVWTTQ 300
PWTIPANQAI CYMPEAKYAV VKCSASGHLY ILAEDKIAPV ASALETTFDV VAAFSGVDLE 360
GGTCSHPLTP DKVSPLLPAT HVTMAKGTGL VHTAPAHGME DYSVASQHSL PMDCLVDEGG 420
MFTDAAGPEL QNKAVLKEGT DVVIKMLQAT KNVLKEENIV HSYPCDWRTK TPVLIRASKQ 480
WFVNITDIKA AAKESLKTVK FIPGAALNSM TDMLDRRPYW CISRQRVWGV PIPVFHHKTK 540
DEYLINRRML SPALLTYALR 561
Keyword

KW-0030--Aminoacyl-tRNA synthetase
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-0648--Protein biosynthesis
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR001412--aa-tRNA-synth_I_CS
IPR002300--aa-tRNA-synth_Ia
IPR002301--Ile-tRNA-ligase
IPR014729--Rossmann-like_a/b/a_fold
IPR009008--Val/Leu/Ile-tRNA-synth_edit
PROSITE

PS00178--AA_TRNA_LIGASE_I
Pfam

PF00133--tRNA-synt_1
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0002161--F:aminoacyl-tRNA editing activity
GO:0005524--F:ATP binding
GO:0004822--F:isoleucine-tRNA ligase activity
GO:0006428--P:isoleucyl-tRNA aminoacylation
GO:0032543--P:mitochondrial translation