dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050668
Uniprot Accession E9PWI3; E9PWI3_MOUSE;
Genbank Protein ID NP_001078842.1;
Genbank Nucleotide ID NM_001085373.1;
Protein Name Protein Mcc
Protein Synonyms/Alias
Gene Name Mcc
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 30 (View all)
PositionPeptidesSourceReferences ( PMIDs )
144SGARDLQSPDLQSQRcurated25338131
258LRYEERITELHSIIAPhosphoSitePlus22135298
262ERITELHSIIAELNKPhosphoSitePlus22135298
286IREEDEYSELRSELScurated25338131
290DEYSELRSELSQSQQcurated25338131
293SELRSELSQSQQEVNcurated25338131
295LRSELSQSQQEVNEDPhosphoSitePlus;curated22135298; 25338131
346RVLTGLESVVCGRKKcurated25338131
354VVCGRKKSSCSLSVAPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 21183079; 25338131
355VCGRKKSSCSLSVADPhosphoSitePlus;curated22135298; 23567750; 25338131
357GRKKSSCSLSVADVDPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 23567750; 25338131
359KKSSCSLSVADVDRHPhosphoSitePlus;curated22135298; 25338131
371DRHIEQLTTASEHCDPhosphoSitePlus;curated22135298; 25338131
374IEQLTTASEHCDLAIPhosphoSitePlus;curated22135298; 25338131
468SVQATGPSSPGRLTPcurated25338131
469VQATGPSSPGRLTPAPHOSIDA;PhosphoSitePlus;SysPTM 2.0;curated21081558; 22135298; 17242355; 19366988; 21183079; 25338131
490STGELSTSSSSNDIPcurated25338131
492GELSTSSSSNDIPIAcurated25338131
659FRAAGVGSSPGDQSGcurated25338131
660RAAGVGSSPGDQSGDcurated25338131
Sequence
(Fasta)		MAAASACNSS GGSSDTSSTG EEERLRRLFQ TCDGDGDGYI SRNDLLMVCR QLSMEESVAE 60
IMNQLGSDEN GKISFQDFTR CHTQLVREIR KEEGDLSMKS DMSSTKRLSE RITSWPTSSD 120
NSLGALSAAR ESWEDDSGAR DLQSPDLQSQ RPLQKLLEYG GSSLPQQAVL HKLLTHAPNF 180
GTSTGGSYLE LASTLHLAAL ASLKGDIVEL NKRLQQTERE RDLLEKKLAK AQCEQSHLMR 240
EHEDVQERTT LRYEERITEL HSIIAELNKK IDRLQGTTIR EEDEYSELRS ELSQSQQEVN 300
EDSRSVDQDQ TSVSIPENQS TMVTADMDNC SDLNSELQRV LTGLESVVCG RKKSSCSLSV 360
ADVDRHIEQL TTASEHCDLA IKTVEEIEGV LGRDLYPNLA EERSRWEKEL AGLREENESL 420
TAMLCSKEEE LNRTKATMNA IREERDRLRR RVRELQTRLQ SVQATGPSSP GRLTPANRPI 480
NPSTGELSTS SSSNDIPIAK IAERVKLSKT RSESSSSDRP VLGSEISSIG VSSSVAEHLA 540
HSLQDCSNIQ EIFQTLYSHG SAISESKIRE FEVETERLNS RIEHLKSQND LLTITLEECK 600
SNAERMSMLV GKYESNATAL RLALQYSEQC IEAYELLLAL AESEQSLILG QFRAAGVGSS 660
PGDQSGDENI TQMLKRAHDC RKTAENAAKA LLMKLDGSCG GAFAVAGCSV QPWESLSSNS 720
HTSTTSSTAS SCDTEFTKED EQRLKDYIQQ LKNDRAAVKL TMLELESIHI DPLSYDVKPR 780
GDSQRLDLEN AVLMQELMAM KEEMAELKAQ LYLLEKEKKA LELKLSTREA QEQAYLVHIE 840
HLKSEVEEQK EQRTRSLSST SSSGKEKPGK ECADAASPAL SLAELRTNSD SELATEFANA 900
IRREKKLKAR VQELVSALER LTKSSEIRHQ QSAEFVNDLK RANSNLVAAY EKAKKKHQNK 960
LKKLESQMMA MVERHETQVR MLKQRIALLE EENSRPHTNE TSL 1004
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR019536--USH1C-bd_PDZ_domain
PROSITE

PS00018--EF_HAND_1
PS50222--EF_HAND_2
Pfam

PF13499--EF-hand_7
PF10506--MCC-bdg_PDZ
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0045184--P:establishment of protein localization
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0010633--P:negative regulation of epithelial cell migration
GO:0050680--P:negative regulation of epithelial cell proliferation