dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050656
Uniprot Accession E9PW37; E9PW37_MOUSE;
Genbank Protein ID NP_808312.3;
Genbank Nucleotide ID NM_177644.5;
Protein Name Protein Rasal2
Protein Synonyms/Alias
Gene Name Rasal2
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 41 (View all)
PositionPeptidesSourceReferences ( PMIDs )
131KGRCLRRTVSVPSEGPhosphoSitePlus22135298
133RCLRRTVSVPSEGQFPhosphoSitePlus;SysPTM 2.0;curated22135298; 18056256; 19366988; 21183079; 25338131
158LEVPAERSPRRRSISPHOSIDA;PhosphoSitePlus;SysPTM 2.0;curated21081558; 22135298; 18056256; 19366988; 22817900; 21183079;
163ERSPRRRSISGTSTSPhosphoSitePlus;curated22135298; 23684622; 22817900; 21183079; 25338131
165SPRRRSISGTSTSEKPhosphoSitePlus22135298
170SISGTSTSEKPNSMDPhosphoSitePlus;curated22135298; 21183079
178EKPNSMDTANTSPFKPhosphoSitePlus22135298
181NSMDTANTSPFKVPGcurated22807455
182SMDTANTSPFKVPGFPhosphoSitePlus22135298
212SKLDRNTSFRLPSLRPhosphoSitePlus;curated22135298; 22817900; 21183079
236PKLKESRSHESLLSPPhosphoSitePlus;curated22135298; 22817900; 21183079
239KESRSHESLLSPCSAPhosphoSitePlus;curated22135298; 22817900; 21183079; 25338131
242RSHESLLSPCSAVECPhosphoSitePlus;curated22135298; 21183079
767TKSLTNPTPIQQQLRPHOSIDA;PhosphoSitePlus;SysPTM 2.0;curated21081558; 22135298; 18056256; 19366988; 22817900; 21183079
780LRRFAEHSSSPNVSGcurated25338131
781RRFAEHSSSPNVSGSPhosphoSitePlus22135298
782RFAEHSSSPNVSGSLcurated21183079; 25338131
788SSPNVSGSLSSGLQRPhosphoSitePlus;curated22135298; 22817900; 21183079; 25338131
790PNVSGSLSSGLQRICPhosphoSitePlus;curated22135298; 22817900; 21183079
810SDLHKLKSPSQDNTDPhosphoSitePlus;curated22135298; 25338131
Sequence
(Fasta)		MELSPSSGGA AEALSWPEMF TGLESDSPLP PEDLDAVVPV SGAVAGGMLD RILLESVCQQ 60
QSWVRVFDVK GPPTHRLSCG QSPYTETTSW ERKYCILTDS QLVLLNKEKE MPVEGQDQQT 120
DSTKGRCLRR TVSVPSEGQF PEYPQEGTTK LEVPAERSPR RRSISGTSTS EKPNSMDTAN 180
TSPFKVPGFF SKRLKGSIKR TKSQSKLDRN TSFRLPSLRN ADDRSRGLPK LKESRSHESL 240
LSPCSAVECL DLGRGEPVSV KPLHSSILGQ DFCFEVTYLS GSKCFSCSSA SERDKWMENL 300
RRTVQPNKDN CRRAENVLRL WIIEAKDLAP KKKYFCELCL DDTLFARTTS KTKADNIFWG 360
EHFEFYSLPP LHSITVHIYK DVEKKKKKDK NNYVGLVNIP TASVTGRQFV EKWYPVSTPT 420
PNKGKTGGPS IRIKSRFQTI TILPMEQYKE FAEFITSNYT MLCSVLEPVI SVRNKEELAC 480
ALVHILQSTG RAKDFLTDLV MSEVDRCGEH DVLIFRENTI ATKSIEEYLK LVGQQYLHDA 540
LGEFIKALYE SDENCEVDPS KCSSSELMDH QSNLKMCCEL AFCKIINSYC VFPRELKEVF 600
ASWKQQCLNR GKQDISERLI SASLFLRFLC PAIMSPSLFN LMQEYPDDRT SRTLTLIAKV 660
IQNLANFAKF GNKEEYMAFM NDFLEHEWGG MKRFLLEISN PDTISNTPGF DGYIDLGREL 720
SVLHSLLWEV VSQLDKGENS FLQATVAKLG PLPRVLADIT KSLTNPTPIQ QQLRRFAEHS 780
SSPNVSGSLS SGLQRICEDP TDSDLHKLKS PSQDNTDSYF RGKTLLLVQQ ASSQSMTYSE 840
KDEKENSLPN GRSISLMDLQ DTHAAQAEHA SVMLDVPMRL AGSQLSITQV ASIKQLRETQ 900
STPQSAPQVR RPLHPALNQP GSLQPLSFQN PVYHLNNPVP AMPKASADSS LENLSTASSR 960
SQSNSEDFKL SGPSNSSMED FTKRSSHSED FSRRHTVPDR HIPLALPRQN STGQSQIRKL 1020
DHSGLGARAK APPSLPHSAS LRSTGSMSVA SAALMAEPVQ NGSRSRQQSS SSRESPVPKV 1080
RAIQRQQTQQ VQSPVDSATM SPVERTAAWV LNNGQYEEDV EETEQNQDEA KHAEKYEQEI 1140
TKLKERLRVS SRRLEEYERR LLVQEQQMQK LLLEYKARLE DSEERLRRQQ EEKDSQMKSI 1200
ISRLMAVEEE LKKDHAEMQA VIDAKQKIID AQEKRIVSLD SANTRLMSAL TQVKERYSMQ 1260
VRNGISPTNP TKLSITENGE FKNSSC 1287
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR000008--C2_dom
IPR021887--DUF3498
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR023152--RasGAP_CS
IPR001936--RasGAP_dom
IPR008936--Rho_GTPase_activation_prot
PROSITE

PS50003--PH_DOMAIN
PS00509--RAS_GTPASE_ACTIV_1
PS50018--RAS_GTPASE_ACTIV_2
Pfam

PF00168--C2
PF12004--DUF3498
PF00616--RasGAP
Gene Ontology

GO:0005737--C:cytoplasm
GO:0031235--C:intrinsic component of the cytoplasmic side of the plasma membrane
GO:0005096--F:GTPase activator activity
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0043547--P:positive regulation of GTPase activity
GO:0007165--P:signal transduction