| Tag |
Content |
| dbPAF ID |
dbPAF-0050654 |
| Uniprot Accession |
E9PW06; E9PW06_MOUSE;
|
| Genbank Protein ID |
NP_001153789.1;
|
| Genbank Nucleotide ID |
NM_001160317.1;
|
| Protein Name |
Neurofascin |
| Protein Synonyms/Alias |
|
| Gene Name |
Nfasc |
| Gene Synonyms/Alias |
|
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 4 |
Sequence
(Fasta) | MARQQAPPWV HIALILFLLS LGGAIEIPMD LTQPPTITKQ SVKDHIVDPR DNILIECEAK 60
GNPAPSFHWT RNSRFFNIAK DPRVSMRRRS GTLVIDFRSG GRPEEYEGEY QCFARNKFGT 120
ALSNRIRLQV SKSPLWPKEN LDPVVVQEGA PLTLQCNPPP GLPSPVIFWM SSSMEPITQD 180
KRVSQGHNGD LYFSNVMLQD MQTDYSCNAR FHFTHTIQQK NPFTLKVLTN NPYNDSSLRN 240
HPDIYSARGV AERTPSFMYP QGTSSSQMVL RGMDLLLECI ASGVPTPDIA WYKKGGDLPS 300
NKAKFENFNK ALRITNVSEE DSGEYFCLAS NKMGSIRHTI SVRVKAAPYW LDEPKNLILA 360
PGEDGRLVCR ANGNPKPTVQ WMVNGEPLQS APPNPNREVA GDTIIFRDTQ ISSRAVYQCN 420
TSNEHGYLLA NAFVSVLDVP PRMLSARNQL IRVILYNRTR LDCPFFGSPI PTLRWFKNGQ 480
GSNLDGGNYH VYENGSLEIK MIRKEDQGIY TCVATNILGK AENQVRLEVK DPTRIYRMPE 540
DQVAKRGTTV QLECRVKHDP SLKLTVSWLK DDEPLYIGNR MKKEDDSLTI FGVAERDQGS 600
YTCMASTELD QDLAKAYLTV LGRPDRPRDL ELTDLAERSV RLTWIPGDDN NSPITDYVVQ 660
FEEDQFQPGV WHDHSRFPGS VNSAVLHLSP YVNYQFRVIA VNEVGSSHPS LPSERYRTSG 720
APPESNPSDV KGEGTRKNNM EITWTPMNAT SAFGPNLRYI VKWRRRETRE TWNNVTVWGS 780
RYVVGQTPVY VPYEIRVQAE NDFGKGPEPD TIIGYSGEDY PRAAPTEVKI RVLNSTAISL 840
QWNRVYSDTV QGQLREYRAY YWRESSLLKN LWVSQKRQQA SFPGDRPRGV VARLFPYSNY 900
KLEMVVVNGR GDGPRSETKE FTTPEGVPSA PRRFRVRQPN LETINLEWDH PEHPNGILIG 960
YILRYVPFNG TKLGKQMVEN FSPNQTKFSV QRADPVSRYR FSLSARTQVG SGEAATEESP 1020
APPNEATPTA AYTNNQADIA TQGWFIGLMC AIALLVLILL IVCFIKRSRG GKYPVREKKD 1080
VPLGPEDPKE EDGSFDYSDE DNKPLQGSQT SLDGTIKQQE SDDSLVDYGE GGEGQFNEDG 1140
SFIGQYTVKK DKEETEGNES SEATSPVNAI YSLA
1175Fasta Sequence
>E9PW06|Nfasc|Mus musculus(Mouse)
MARQQAPPWVHIALILFLLSLGGAIEIPMDLTQPPTITKQSVKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNNPYNDSSLRNHPDIYSARGVAERTPSFMYPQGTSSSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSNKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSARNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVAKRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCMASTELDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTWIPGDDNNSPITDYVVQFEEDQFQPGVWHDHSRFPGSVNSAVLHLSPYVNYQFRVIAVNEVGSSHPSLPSERYRTSGAPPESNPSDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRETWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPDTIIGYSGEDYPRAAPTEVKIRVLNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRPRGVVARLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGILIGYILRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRFSLSARTQVGSGEAATEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA
|
| Keyword |
KW-0181--Complete proteome
KW-0393--Immunoglobulin domain
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
|
| Interpro |
IPR003961--FN3_dom
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR013098--Ig_I-set
IPR003599--Ig_sub
IPR003598--Ig_sub2
IPR013151--Immunoglobulin
IPR026966--Neurofascin/L1/NrCAM_C
|
| PROSITE |
PS50853--FN3
PS50835--IG_LIKE
|
| Pfam |
PF13882--Bravo_FIGEY
PF00041--fn3
PF07679--I-set
PF00047--ig
|
| Gene Ontology |
GO:0030424--C:axon
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0016021--C:integral component of membrane
GO:0033010--C:paranodal junction
GO:0033270--C:paranode region of axon
GO:0005886--C:plasma membrane
GO:0086080--F:protein binding involved in heterotypic cell-cell adhesion
GO:0007411--P:axon guidance
GO:0045162--P:clustering of voltage-gated sodium channels
GO:0034113--P:heterotypic cell-cell adhesion
GO:0030913--P:paranodal junction assembly
GO:0071205--P:protein localization to juxtaparanode region of axon
GO:0002175--P:protein localization to paranode region of axon
GO:0050808--P:synapse organization
GO:0019226--P:transmission of nerve impulse
|
