dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050649
Uniprot Accession E9PVX6; E9PVX6_MOUSE;
Genbank Protein ID NP_001074586.2;
Genbank Nucleotide ID NM_001081117.2;
Protein Name Protein Mki67
Protein Synonyms/Alias
Gene Name Mki67
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 171 (View all)
PositionPeptidesSourceReferences ( PMIDs )
125KEPSRRASRDSFCADPhosphoSitePlus;curated22135298; 22817900; 21183079; 25338131
128SRRASRDSFCADPDGPhosphoSitePlus;curated22135298; 22817900; 21183079; 25338131
151KMTASRRSFVYAKGLPhosphoSitePlus;curated22135298; 22817900; 21183079
162AKGLSADSPASDGSKPhosphoSitePlus;curated22135298; 22817900; 21183079
212SSYREPKSSPTQSLSPhosphoSitePlus;curated22135298; 25338131
213SYREPKSSPTQSLSNPhosphoSitePlus;curated22135298; 25338131
215REPKSSPTQSLSNSNPhosphoSitePlus22135298
217PKSSPTQSLSNSNEKPhosphoSitePlus22135298
226SNSNEKESPFEKLYQcurated25338131
276SGRARAKSSGSTPVTPhosphoSitePlus;curated22135298; 21183079; 25338131
277GRARAKSSGSTPVTAPhosphoSitePlus;curated22135298; 21183079; 25338131
279ARAKSSGSTPVTAASPhosphoSitePlus;curated22135298; 21183079
280RAKSSGSTPVTAASSPhosphoSitePlus;curated22135298; 21183079
283SSGSTPVTAASSPKVPhosphoSitePlus;curated22135298; 21183079
286STPVTAASSPKVGKIPhosphoSitePlus;curated22135298; 21183079; 25338131
287TPVTAASSPKVGKIWPhosphoSitePlus;curated22135298; 21743459; 21183079
337RVTGRRHSVNLDEGEPhosphoSitePlus;curated22135298; 25338131
373VEAGDVASPADTPEHPhosphoSitePlus;curated22135298; 25338131
377DVASPADTPEHSSSKPhosphoSitePlus;curated22135298; 25338131
404AETQKRLSLTQRLVPPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 18846507
Sequence
(Fasta)		MASSAHLVTI KRSGDDGAHF PLSLSSCLFG RSIECDIRIQ LPVVSKRHCK IEVKEQEAIL 60
YNFSSTNPTQ VNGVTIDEPV RLRHGDIITI IDRSFRYEDG NHEDGSKPTE FPGKSLGKEP 120
SRRASRDSFC ADPDGEGQDT KASKMTASRR SFVYAKGLSA DSPASDGSKN SVSQDSSGHV 180
EQHTGRNIVE PTSGDLFKKS RSTGSSYREP KSSPTQSLSN SNEKESPFEK LYQSMKEELD 240
VKSQKSCRKS EPQPDRAAEE SRETQLLVSG RARAKSSGST PVTAASSPKV GKIWTERWRG 300
GMVPVQTSTE TAKMKTPVRH SQQLKDEDSR VTGRRHSVNL DEGESAQAVH KTVTPGKLAT 360
RNQAAVEAGD VASPADTPEH SSSKKRSIPA KVEAPSAETQ KRLSLTQRLV PGEKKTPKGS 420
FSKPEKLATA AEQTCSGLPG LSSVDISNFG DSINKSEGMP MKRRRVSFGG HLRPELFDEN 480
LPPNTPLKRG ETPTKRKSLG THSPAVLKTI IKERPQSPGK QESPGITPPR TNDQRRRSGR 540
TSSGSKFLCE TDIPKKAGRK SGNLPAKRAS ISRSQHGILQ MICSKRRSGA SEANLIVAKS 600
WADVVKLGVK QTQTKVAKHV PQKQTSKRQR RPSTPKKPTS NLHNQFTTGH ANSPCTIVVG 660
RAQIEKVSVP ARPYKMLNNL MLNRKVDFSE DLSGLTEMFK TPVKEKQQQM SDTGSVLSNS 720
ANLSERQLQV TNSGDIPEPI TTEILGEKVL SSTRNAAKQQ SDRYSASPTL RRRSIKHENT 780
VQTPKNVHNI TDLEKKTPVS ETEPLKTASS VSKLRRSREL RHTLVETMNE KTEAVLAENT 840
TARHLRGTFR EQKVDQQVQD NENAPQRCKE SGELSEGSEK TSARRSSARK QKPTKDLLGS 900
QMVTQTADYA EELLSQGQGT IQNLEESMHM QNTSISEDQG ITEKKVNIIV YATKEKHSPK 960
TPGKKAQPLE GPAGLKEHFE TPNPKDKPIT EDRTRVLCKS PQVTTENITT NTKPQTSTSG 1020
KKVDMKEESS ALTKRIHMPG ESRHNPKILK LECEDIKALK QSENEMLTST VNGSKRTLEK 1080
SKKKAQPLED LTCFQELFIS PVPTNIIKKI PSKSPHTQPV RTPASTKRLS KTGLSKVDVR 1140
QEPSTLGKRT KSPGRAPGTP APVQEENDST AFMETPKQKL DFAGNSSGSK RRSRTSKNRS 1200
QPLEDLDGFQ ELFQTPAGAS DSVTVEESAK ISLESSQAEP VKTPASTKRR SKMSLMKVDM 1260
KELSILEKQT QSRGRDAGTP APMQEGNGTT AIMETPKQKL DFTGNSTGHK RRPRTPKIRA 1320
QPLEDLDGFQ ELFQTPAGAN DSVTVEESAK MSLESSQAEP VKTPASTKRL SKTDLSKVDV 1380
REDPSILGKK TKSPGRAPGT PAPVQEENDC TAYMETPKQK LESIENLTGL RKQSRTPKDI 1440
TGFQDSFQIP DHANGPLVVV KTKKMFFNSP QPESAITRKS RERQSRASIS KIDVKEELLE 1500
SEEHLQLGEG VDTFQVSTNK VIRSSRKPAK RKLDSTAGMP NSKRMRCSSK DNTPCLEDLN 1560
GFQELFQMPG YANDSLTTGI STMLARSPQL GPVRTQINKK SLPKIILRKM DVTEEISGLW 1620
KQSLGRVHTT QEQEDNAIKA IMEIPKETLQ TAADGTRLTR QPQTPKEKVQ PLEDHSVFQE 1680
LFQTSRYCSD PLIGNKQTRM SLRSPQPGFV RTPRTSKRLA KTSVGNIAVR EKISPVSLPQ 1740
CATGEVVHIP IGPEDDTENK GVKESTPQTL DSSASRTVSK RQQGAHEERP QFSGDLFHPQ 1800
ELFQTPASGK DPVTVDETTK IALQSPQPGH IINPASMKRQ SNMSLRKDMR EFSILEKQTQ 1860
SRGRDAGTPA PMQEENGTTA IMETPKQKLD FIGNSTGHKR RPRTPKNRAQ PLEDLDGFQE 1920
LFQTPAGASD PVSVEESAKI SLASSQAEPV RTPASTKRRS KTGLSKVDVR QEPSTLGKRM 1980
KSLGRAPGTP APVQEENDST AFMETPKQKL DFTGNSSGHK RRPQTPKIRA QPLEDLDGFQ 2040
ELFQTPAGAN DSVTVEESVK MSLESSQAEP VKTPASTKRL SKTGLSKVDV REDPSILEKK 2100
TKSPGTPAPV QEENDCTAFM ETPKQKLDFT GNSSGHKRRP RTPKIRAQPL EDLDGFQELF 2160
QTPAGASDSV TVEESAKMSL ESSQAKPVKT PASTKRLSKT GLSKVDVRED PSTLGKKTKS 2220
PGRAPGTPAP VQEENDSTAF METPKQKLDF AENSSGSKRR SRTSKNRSQP LEDLDGFQEL 2280
FQTPAGASNP VSVEESAKIS LESSQAEPVR TRASTKRLSK TGLNKMDVRE GHSPLSKSSC 2340
ASQKVMQTLT LGEDHGRETK DGKVLLAQKL EPAIYVTRGK RQQRSCKKRS QSPEDLSGVQ 2400
EVFQTSGHNK DSVTVDNLAK LPSSSPPLEP TDTSVTSRRQ ARTGLRKVHV KNELSGGIMH 2460
PQISGEIVDL PREPEGEGKV IKTRKQSVKR KLDTEVNVPR SKRQRITRAE KTLEDLPGFQ 2520
ELCQAPSLVM DSVIVEKTPK MPDKSPEPVD TTSETQARRR LRRLVVTEEP IPQRKTTRVV 2580
RQTRNTQKEP ISDNQGMEEF KESSVQKQDP SVSLTGRRNQ PRTVKEKTQP LEELTSFQEE 2640
TAKRISSKSP QPEEKETLAG LKRQLRIQLI NDGVKEEPTA QRKQPSRETR NTLKEPVGDS 2700
INVEEVKKST KQKIDPVASV PVSKRPRRVP KEKAQALELA GLKGPIQTLG HTDESASDKG 2760
PTQMPCNSLQ PEQVDSFQSS PRRPRTRRGK VEADEEPSAV RKTVSTSRQT MRSRKVPEIG 2820
NNGTQVSKAS IKQTLDTVAK VTGSRRQLRT HKDGVQPLEV LGDSKEITQI SDHSEKLAHD 2880
TSILKSTQQQ KPDSVKPLRT CRRVLRASKE DPKEVLVDTR DHATLQSKSN PLLSPKRKSA 2940
RDGSIVRTRA LRSLAPKQEA TDEKPVPEKK RAASSKRHVS PEPVKMKHLK IVSNKLESVE 3000
EQVSTVMKTE EMEAKRENPV TPDQNSRYRK KTNVKQPRPK FDASAENVGI KKNEKTMKTA 3060
SQETELQNPD DGAKKSTSRG QVSGKRTCLR SRGTTEMPQP CEAEEKTSKP AAEILIKPQE 3120
EKGVSGESDV RCLRSRKTRV ALDSEPKPRV TRGTKKDAKT LKEDEDIVCT KKLRTRS 3178
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR000253--FHA_dom
IPR012568--K167R
IPR029334--PP1-bd
IPR008984--SMAD_FHA_domain
PROSITE

PS50006--FHA_DOMAIN
Pfam

PF00498--FHA
PF08065--K167R
PF15276--PP1_bind
Gene Ontology

GO:0000775--C:chromosome, centromeric region
GO:0000793--C:condensed chromosome
GO:0005737--C:cytoplasm
GO:0016020--C:membrane
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0044822--F:poly(A) RNA binding
GO:0008022--F:protein C-terminus binding
GO:0008283--P:cell proliferation
GO:0034605--P:cellular response to heat
GO:1990705--P:cholangiocyte proliferation
GO:0006259--P:DNA metabolic process
GO:0072574--P:hepatocyte proliferation
GO:0030212--P:hyaluronan metabolic process
GO:0007126--P:meiotic nuclear division
GO:0031100--P:organ regeneration
GO:0014070--P:response to organic cyclic compound