dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050646
Uniprot Accession E9PVU7; E9PVU7_MOUSE;
Genbank Protein ID XP_006517706.1;
Genbank Nucleotide ID XM_006517643.1;
Protein Name cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Protein Synonyms/Alias
Gene Name Pde4d
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
14SVPARAVSEEGNDSAPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 21183079; 25521595
134HRPGLKKSRMSWPSSPhosphoSitePlus;SysPTM 2.022135298; 17203969; 19366988
137GLKKSRMSWPSSFQGPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 21183079
Sequence
(Fasta)		MEAEGSSVPA RAVSEEGNDS AGGAALKAPK HLWRHEQHHQ YPLRQPQFRL LHPHHHLPPP 60
PPPSPQPQLQ PPPPPPLPPP PPPPGATRGR YASSGASRVR HRGYSDTERY LYCRAMDRTS 120
YAVETGHRPG LKKSRMSWPS SFQGLRRFDV DNGTSAGRSP LDPMTSPGSG LILQANFVHS 180
QRRESFLYRS DSDYDLSPKS MSRNSSIASD IHGDDLIVTP FAQVLASLRT VRNNFAALTN 240
LQDRAPSKRS PMCNQPSINK ATITEEAYQK LASETLEELD WCLDQLETLQ TRHSVSEMAS 300
NKFKRMLNRE LTHLSEMSRS GNQVSEYISN TFLDKQHEVE IPSPTQKEKE KKKRPMSQIS 360
GVKKLMHSSS LTNSCIPRFG VKTEQEDVLA KELEDVNKWG LHVFRIAELS GNRPLTVIMH 420
TIFQERDLLK TFKIPVDTLI TYLMTLEDHY HADVAYHNNI HAADVVQSTH VLLSTPALEA 480
VFTDLEILAA IFASAIHDVD HPGVSNQFLI NTNSELALMY NDSSVLENHH LAVGFKLLQE 540
ENCDIFQNLT KKQRQSLRKM VIDIVLATDM SKHMNLLADL KTMVETKKVT SSGVLLLDNY 600
SDRIQVLQNM VHCADLSNPT KPLQLYRQWT DRIMEEFFRQ GDRERERGME ISPMCDKHNA 660
SVEKSQVGFI DYIVHPLWET WADLVHPDAQ DILDTLEDNR EWYQSTIPQS PSPAPDDQEE 720
GRQGQTEKFQ FELTLEEDCE SDTEKDSGSQ VEEDTSCSDS KTLCTQDSES TEIPLDEQVE 780
EEAVAEEESQ PETCVPDDCC PDT 804
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR003607--HD/PDEase_dom
IPR023088--PDEase
IPR002073--PDEase_catalytic_dom
IPR023174--PDEase_CS
PROSITE

PS00126--PDEASE_I
Pfam

PF00233--PDEase_I
Gene Ontology

GO:0005813--C:centrosome
GO:0004114--F:3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0046872--F:metal ion binding
GO:0007568--P:aging
GO:0006198--P:cAMP catabolic process
GO:0071222--P:cellular response to lipopolysaccharide
GO:0050900--P:leukocyte migration
GO:0035264--P:multicellular organism growth
GO:0030593--P:neutrophil chemotaxis
GO:0007165--P:signal transduction
GO:0006939--P:smooth muscle contraction