dbPAF Protein Information
Tag | Content | ||||||||
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dbPAF ID | dbPAF-0050639 | ||||||||
Uniprot Accession | E9PVD1; CCD62_MOUSE; F6WEA5; | ||||||||
Genbank Protein ID | NP_001128239.1; XP_006530318.1; | ||||||||
Genbank Nucleotide ID | NM_001134767.1; XM_006530255.2; | ||||||||
Protein Name | Coiled-coil domain-containing protein 62 | ||||||||
Protein Synonyms/Alias | |||||||||
Gene Name | Ccdc62 | ||||||||
Gene Synonyms/Alias | |||||||||
Organism | Mus musculus(Mouse) | ||||||||
NCBI Taxa ID | 10090 | ||||||||
Functional Description (View all) |
Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR (By similarity). | ||||||||
Phosphorylation Sites |
dbPAF PTMs: 1
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Sequence (Fasta) | MRSSEGAPSW AVALPPPLRP CAYGVSEVTR CWHQLSLGAG ESSMNPSATL YRRQNIGSEV 60 ETSTIEKQRK ELQLLIGELK DRDKELNDMV AVHQRQLLSW EEDRQKVLTL EERCSKLEGE 120 LHKRTDIIKS LMKKVKTLES NQAECQTALQ KTQQQLQEMA QKATHSTLLS EDLEARNENL 180 SSTLVDLSAQ VGQLQAREQA LTTMIKLKDK DIIEAVNHIS DCSGKFKLLE HALRDAKMAE 240 TCVVREKQDY KQKLKALRIE VNKLKEDLNE KTTENNEQRE EIIRLKQEKS CLHDELIFTV 300 EREKRKDELL DIAKSKQDRT NSELQNLRQI YVKQQSDLQF LNFNIESSQE LIQIHGLKME 360 EPKALECSKD MCLSDLDNNY PKIDIKRERN QKSLVKDQTF EVMLAQHNGS DKSSCDACRE 420 KKLQVNTALG EKSVIALSSL FTKDLLDKQK SWSLGGKIQT EPENKVTLCK VHAKSPKCDG 480 VGLPTEEKQL SETSVSLSDE KQWHDINVYL GLSSCSKQPD RLDGDGHDRT GTSEVSCCTP 540 NVVCIGDNDL SESKCCHPSN IIIEAPGHMT DTEWMNIFKP SRAQRIVRHK TMCTCSRSVS 600 AMKYNSSASE LIGMQPSQCV GSLKSAEREE ESAALPDRRT SANEKDDFSP TSKLQRLLAE 660 SRQMVTDLEL STLLPISCEN LNRSKLEVSE EPDEKTTLVS H 702 |
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Keyword | KW-0175--Coiled coil |
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Interpro | |||||||||
PROSITE | |||||||||
Pfam | |||||||||
Gene Ontology | GO:0005737--C:cytoplasm |