dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050637
Uniprot Accession E9PVB5; TTC17_MOUSE; Q4VBE5; Q5RKR1;
Genbank Protein ID NP_898929.2; XP_006500374.1;
Genbank Nucleotide ID NM_183106.2; XM_006500311.2;
Protein Name Tetratricopeptide repeat protein 17
Protein Synonyms/Alias
Gene Name Ttc17
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Plays a role in primary ciliogenesis by modulating actin polymerization.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
522LGGELPTYFLPPENKPhosphoSitePlus22135298
Sequence
(Fasta)
MAAAIGVRGR FELLPRSGPG WLLSLSALLS VVARGALATT HWVVTEDGKI QQQVDSPMNL 60
KHPHDLVILM RQETTVNYLK ELEKQLVAQK IHIEENEDRD TGLEQRHNKE DPDCIKAKVP 120
LGDLDLYDGT YITLESKDIR PEDFIDTESP VPPDPEQPDC TKILELPYSI HAFQHLRGVQ 180
ERVNLSAPLL PKEDPIFTYL SKRLGRSIDD IGHLIHEGLQ KNASSWVLYN LASFYWRIKN 240
EPYQVVECAM RALHFSSRHN KDIALVNLAN VLHRAHFSAD AAVVVHAALD DSDFFTSYYT 300
LGNIYAMLGE YNHSVLCYDH ALQAKPGFEQ AIKRKHAVLC QQKLEQKLEA QHRSLQRTLN 360
ELKEYQKQHD HYLRQQEILE KHKLIQEEQI LRNIIHETQM AKEAQLGNHQ ICRLVNQQHS 420
LHCQWDQPVR YHRGDIFENV DYVQFGDDSS TSSMMSVNFD VPTNQSDVSE SVRSSPVAHS 480
VLWVWGRDSD AYRDKQHILW PKRADCTDSY PRVPLGGELP TYFLPPENKG LRIHELTSDD 540
YSSEEEAQPP DCSITDYRKS HTLSYLVKEL EVRMDLKAKI PDDHARKILL SRIKNYTVPE 600
EEIGSFLFHA INKPNAPVWL ILNEAGLYWR AVGNSTFAIA CLQRALNLAP VQYQDIPLVN 660
LANLLIHYGL HLDATKLLLQ AVAVNSSEPL TFLSLGNAYL ALKNVSGALE AFRQALKLST 720
KCPECESSLK LIRCMQFYPF LYNATSSVCG GHCHEKPLDN SHDKQKYFAK PQSLDAAAEE 780
PSGHGADEDP VLSVENAGRD SDALRLESTV VEESNGSDEV EKSDETKMSE EILALVDEFQ 840
QAWPLEGFGG TLEMKGRRLD LQGIRVLKKG PQDGVAKSSC YGDCRSEDDE ATEWITFQVK 900
RVKKPKGDHK KPPGKKVEAS QAENGQRYQA NLEITGPKVA SPGPQEKKRD YQSLGWPSPD 960
ECLKLRWVEL TAIVSTWLAV SSKNIDITEH IDFATPIQQP AMEPLCNGNL PTSMHTLDHL 1020
HGVSNRASLH YTGESQLTEV LQNLGKDQYP QQSLEQIGTR IAKVLEKNQT SWVLSSMAAL 1080
YWRVKGQGKK AIDCLRQALH YAPHQMKDVP LISLANILHN AKLWNDAVIV ATMAVEIAPH 1140
FAVNHFTLGN VYVAMEEFEK ALVWYESTLK LQPEFVPAKN RIQTIQCHLM LKKGRRSP 1199
Keyword

KW-0025--Alternative splicing
KW-1003--Cell membrane
KW-0970--Cilium biogenesis/degradation
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat

Interpro

IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR001440--TPR_1
IPR019734--TPR_repeat

PROSITE

PS50005--TPR
PS50293--TPR_REGION

Pfam

PF00515--TPR_1

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0030041--P:actin filament polymerization
GO:0044782--P:cilium organization