dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050632
Uniprot Accession E9PV87; TALD3_MOUSE; B2RWX3;
Genbank Protein ID NP_001156850.1;
Genbank Nucleotide ID NM_001163378.1;
Protein Name Protein TALPID3
Protein Synonyms/Alias
Gene Name Talpid3
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)		 Required for ciliogenesis and sonic hedgehog/SHH signaling.
Phosphorylation Sites
 dbPAF PTMs: 27 (View all)
PositionPeptidesSourceReferences ( PMIDs )
26RKLREIVSPNQGNKLcurated25338131
84YHQPLLESPPASKKScurated25338131
91SPPASKKSDFSKDAVPhosphoSitePlus22135298
94ASKKSDFSKDAVVRQPhosphoSitePlus22135298
199APLIKVQSDLEAKVNPhosphoSitePlus;curated22135298; 21183079
333TDFDGQKSPLETPAPcurated25338131
415WNLEKRDSTETLHSQcurated25338131
654QIYGKPVYQGHRSTLPhosphoSitePlus22135298
659PVYQGHRSTLKKGPYPhosphoSitePlus22135298
660VYQGHRSTLKKGPYLPhosphoSitePlus22135298
730ADQQYMVSPSREMPTcurated18846507
974LDASVSVSEASEPSAPhosphoSitePlus22135298
989SDIVAGTSSGALQRMPhosphoSitePlus22135298
990DIVAGTSSGALQRMVPhosphoSitePlus22135298
1060RVCAPVATPQPTPPCPhosphoSitePlus;UniProt;curated22135298; 21183079; 22817900; 25338131
1064PVATPQPTPPCSPSPPhosphoSitePlus;UniProt;curated22135298; 21183079; 22817900; 25338131
1068PQPTPPCSPSPVREHPhosphoSitePlus;UniProt;curated22135298; 21183079; 22817900; 25338131
1070PTPPCSPSPVREHVRPhosphoSitePlus;curated22135298; 22817900; 21183079
1080REHVRVKTPDSSPCEPhosphoSitePlus;UniProt;curated22135298; 21183079; 22817900
1083VRVKTPDSSPCESDPPhosphoSitePlus;UniProt;curated22135298; 21183079; 22817900
Sequence
(Fasta)		MKNVEFSLER GQRLKMPARK LREIVSPNQG NKLAVVEDEL PRVPPALAAN KRLAVETRTS 60
SNGTLCGSLD LTSARLYHQP LLESPPASKK SDFSKDAVVR QLPLNKTEEN NAPKANDIFI 120
SQYTMGQKDA LRTVLKQKAQ SMPVFKAVKV HLFEDTSTEK NTVAQETETP PNRIDSATTV 180
AAATAAAIAT AAPLIKVQSD LEAKVNCVGE LLTKLQETDK QLQRVTEHQA SVQSKQEKVH 240
CHDHDKQMNA FMEQHIRHLE KLQQQQIDIQ THFIDAALKA SSLQLGMSTS RAVGKYSGKL 300
GSPSVGSSVF SHNTFVSKRV PLSEDTDFDG QKSPLETPAP RRFAPVPVSR DGKITKRESP 360
TEEKENMEMN SPKGNVRLLE QVLNSNECLT RKTESSDITS LTQPKMGWNL EKRDSTETLH 420
SQIFPSSEER GTAQVPVPKY NDVVHDLGQK KQASDMLQIK QSPVTLRLSD HPHNPALLQT 480
TNTRSVLKDA AKILRGVQNN KKVLEENLEA IVRAKDGAAM YSFINALATN REMSEKIRIR 540
KQVDEWIKII SAEIQDELMR KDYEQKRFDP KNQRNKKALT MSRDIKANNQ EKTVNRSVIP 600
RSHYQKQTQE QFTSPPVRNL PASGPQKERS GLLKSATTLQ DEDYMLQIYG KPVYQGHRST 660
LKKGPYLRFS SPSPKAKPQR PRVIELVKGT KVKSAKTQTD FHAASRMKMD SKIQHPITAL 720
PHADQQYMVS PSREMPTVSG TLEGHLIPMA ILLGQTQSNS DSMPPAGVTV NKPRPVTVTT 780
SIPPASRKGN AGVKKPNVAI VEMKSEKKDP PQLSVQILPS VDIDSVSYSS TDGASSPPSP 840
KEASLPPLHT WIQTPDFMKV DEEEVPLPGT NFDEVIDVIQ EEEKRDEIPE CSAPMLEFNR 900
SVKVVPTKYN GPSFPPVVSA YHPTTDILDK VIERKETLEN SLIQWVEQEI MSRIISGLFP 960
LQQQARLDAS VSVSEASEPS ASDIVAGTSS GALQRMVDAR VPVNSDMVSH FVNEALTETI 1020
AVMLADREAE RQRAAATSVP GDLSGTETNL LARVCAPVAT PQPTPPCSPS PVREHVRVKT 1080
PDSSPCESDP DAASSIKEIR VEKGSDMPAV MLVSTPTRTP VATPPPAAAL TPTLSETSID 1140
KLKLSSPELP KPWDSGDLPL DEENPNSLQE LPHPRAVVMS VANEEPESVD FSAQPAPPEP 1200
APSAPLPEGT KAPSLQRVPS SGSSTLENTL STVTETETLD RHISEGEILF SCGQNLATKR 1260
PGDLFLMNIN DSLSSTLQDA LEMEDDPPSE GQVIRRPHKK RHEDAIVALL TKQQRELLVS 1320
QQEEDLDNSV GELSEGQRLV LKAAEDISAG PSGQMLPPTS PAEPSYQHAD PRLVLQQSDM 1380
ASGNICEDLC ASHGPMSLRE LELQPDSNLI LPITHTTTAV SDGNLPEAAE DFSQYQQKQD 1440
SDIKQVEHKP IQRHLTSVRN KPDSTLSQHQ GGPADLLLIA HVSPARMSVT LPSANLEDCS 1500
QSLSTSSMHG GTESSGTDTF 1521
Keyword

KW-0970--Cilium biogenesis/degradation
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-1017--Isopeptide bond
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0832--Ubl conjugation
Interpro

IPR029246--TALPID3
PROSITE
Pfam

PF15324--TALPID3
Gene Ontology

GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0005737--C:cytoplasm
GO:0042384--P:cilium assembly
GO:0060271--P:cilium morphogenesis
GO:0070201--P:regulation of establishment of protein localization
GO:0007224--P:smoothened signaling pathway